botox

Not applicable. Not applicable. Not applicable. Not applicable.

Read the Medication Guide and, if available, the Read the Medication Guide and, if available, the Read the Medication Guide and, if available, the Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before Patient Information Leaflet provided by your pharmacist before Patient Information Leaflet provided by your pharmacist before Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get an you start using this medication and each time you get an you start using this medication and each time you get an you start using this medication and each time you get an injection. If you have any questions regarding the information, injection. If you have any questions regarding the information, injection. If you have any questions regarding the information, injection. If you have any questions regarding the information, consult your doctor or pharmacist. consult your doctor or pharmacist. consult your doctor or pharmacist. consult your doctor or pharmacist. This medication is given by injection by an experienced health This medication is given by injection by an experienced health This medication is given by injection by an experienced health This medication is given by injection by an experienced health care professional. It is injected into the affected muscles care professional. It is injected into the affected muscles care professional. It is injected into the affected muscles care professional. It is injected into the affected muscles (intramuscularly) when treating eye disorders, muscle spasms and (intramuscularly) when treating eye disorders, muscle spasms and (intramuscularly) when treating eye disorders, muscle spasms and (intramuscularly) when treating eye disorders, muscle spasms and wrinkles. When used to prevent migraines, it is injected into the wrinkles. When used to prevent migraines, it is injected into the wrinkles. When used to prevent migraines, it is injected into the wrinkles. When used to prevent migraines, it is injected into the muscles of the head and neck. It is injected into the skin muscles of the head and neck. It is injected into the skin muscles of the head and neck. It is injected into the skin muscles of the head and neck. It is injected into the skin (intradermally) for the treatment of excessive sweating. (intradermally) for the treatment of excessive sweating. (intradermally) for the treatment of excessive sweating. (intradermally) for the treatment of excessive sweating. Your dose, the number of injections, the site of injections, Your dose, the number of injections, the site of injections, Your dose, the number of injections, the site of injections, Your dose, the number of injections, the site of injections, and how often you receive the medication will be determined by and how often you receive the medication will be determined by and how often you receive the medication will be determined by and how often you receive the medication will be determined by your condition and your response to therapy. Most people start to your condition and your response to therapy. Most people start to your condition and your response to therapy. Most people start to your condition and your response to therapy. Most people start to see an effect within a few days to 2 weeks, and the effect see an effect within a few days to 2 weeks, and the effect see an effect within a few days to 2 weeks, and the effect see an effect within a few days to 2 weeks, and the effect usually lasts 3 to 6 months. usually lasts 3 to 6 months. usually lasts 3 to 6 months. usually lasts 3 to 6 months.

Drug interactions may change how your Drug interactions may change how your Drug interactions may change how your Drug interactions may change how your medications work or increase your risk for serious side effects. medications work or increase your risk for serious side effects. medications work or increase your risk for serious side effects. medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. This document does not contain all possible drug interactions. This document does not contain all possible drug interactions. This document does not contain all possible drug interactions. Keep a list of all the products you use (including Keep a list of all the products you use (including Keep a list of all the products you use (including Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share prescription/nonprescription drugs and herbal products) and share prescription/nonprescription drugs and herbal products) and share prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change it with your doctor and pharmacist. Do not start, stop, or change it with your doctor and pharmacist. Do not start, stop, or change it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. the dosage of any medicines without your doctor's approval. the dosage of any medicines without your doctor's approval. the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: Some products that may interact with this drug include: Some products that may interact with this drug include: Some products that may interact with this drug include: certain antibiotics (e.g., aminoglycosides such as gentamicin, certain antibiotics (e.g., aminoglycosides such as gentamicin, certain antibiotics (e.g., aminoglycosides such as gentamicin, certain antibiotics (e.g., aminoglycosides such as gentamicin, polymyxin), anticoagulants (e.g., warfarin), Alzheimer's disease polymyxin), anticoagulants (e.g., warfarin), Alzheimer's disease polymyxin), anticoagulants (e.g., warfarin), Alzheimer's disease polymyxin), anticoagulants (e.g., warfarin), Alzheimer's disease drugs (e.g., donepezil, galantamine, rivastigmine, tacrine), drugs (e.g., donepezil, galantamine, rivastigmine, tacrine), drugs (e.g., donepezil, galantamine, rivastigmine, tacrine), drugs (e.g., donepezil, galantamine, rivastigmine, tacrine), myasthenia gravis drugs (e.g., ambenonium, pyridostigmine), myasthenia gravis drugs (e.g., ambenonium, pyridostigmine), myasthenia gravis drugs (e.g., ambenonium, pyridostigmine), myasthenia gravis drugs (e.g., ambenonium, pyridostigmine), quinidine. quinidine. quinidine. quinidine.

It is important to understand the risks and benefits of It is important to understand the risks and benefits of It is important to understand the risks and benefits of It is important to understand the risks and benefits of this therapy. Discuss any questions or concerns with your health this therapy. Discuss any questions or concerns with your health this therapy. Discuss any questions or concerns with your health this therapy. Discuss any questions or concerns with your health care professional. care professional. care professional. care professional.

If overdose is suspected, contact your local poison If overdose is suspected, contact your local poison If overdose is suspected, contact your local poison If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can control center or emergency room immediately. US residents can control center or emergency room immediately. US residents can control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian call the US national poison hotline at 1-800-222-1222. Canadian call the US national poison hotline at 1-800-222-1222. Canadian call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. residents should call their local poison control center directly. residents should call their local poison control center directly. residents should call their local poison control center directly. An antitoxin is available but must be used before symptoms of An antitoxin is available but must be used before symptoms of An antitoxin is available but must be used before symptoms of An antitoxin is available but must be used before symptoms of overdose become apparent. Symptoms of overdose may be delayed, overdose become apparent. Symptoms of overdose may be delayed, overdose become apparent. Symptoms of overdose may be delayed, overdose become apparent. Symptoms of overdose may be delayed, and may include serious muscle weakness, breathing problems and and may include serious muscle weakness, breathing problems and and may include serious muscle weakness, breathing problems and and may include serious muscle weakness, breathing problems and paralysis. paralysis. paralysis. paralysis.

Before using this medication, tell your doctor or Before using this medication, tell your doctor or Before using this medication, tell your doctor or Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other pharmacist if you are allergic to it; or if you have any other pharmacist if you are allergic to it; or if you have any other pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which allergies. This product may contain inactive ingredients, which allergies. This product may contain inactive ingredients, which allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your can cause allergic reactions or other problems. Talk to your can cause allergic reactions or other problems. Talk to your can cause allergic reactions or other problems. Talk to your pharmacist for more details. pharmacist for more details. pharmacist for more details. pharmacist for more details. Before using this medication, tell your doctor your medical Before using this medication, tell your doctor your medical Before using this medication, tell your doctor your medical Before using this medication, tell your doctor your medical history, especially of: bleeding problems, eye surgery, certain history, especially of: bleeding problems, eye surgery, certain history, especially of: bleeding problems, eye surgery, certain history, especially of: bleeding problems, eye surgery, certain eye problem (glaucoma), heart disease, signs of infection near eye problem (glaucoma), heart disease, signs of infection near eye problem (glaucoma), heart disease, signs of infection near eye problem (glaucoma), heart disease, signs of infection near the injection site, muscle/nerve disorders such as Lou Gehrig's the injection site, muscle/nerve disorders such as Lou Gehrig's the injection site, muscle/nerve disorders such as Lou Gehrig's the injection site, muscle/nerve disorders such as Lou Gehrig's disease (ALS) or myasthenia gravis, seizures, trouble swallowing disease (ALS) or myasthenia gravis, seizures, trouble swallowing disease (ALS) or myasthenia gravis, seizures, trouble swallowing disease (ALS) or myasthenia gravis, seizures, trouble swallowing (dysphagia), breathing problems (such as asthma, emphysema, (dysphagia), breathing problems (such as asthma, emphysema, (dysphagia), breathing problems (such as asthma, emphysema, (dysphagia), breathing problems (such as asthma, emphysema, aspiration-type pneumonia). aspiration-type pneumonia). aspiration-type pneumonia). aspiration-type pneumonia). This drug may make cause muscle weakness, droopy eyelids, or This drug may make cause muscle weakness, droopy eyelids, or This drug may make cause muscle weakness, droopy eyelids, or This drug may make cause muscle weakness, droopy eyelids, or blurred vision. Do not drive, use machinery, or do any activity blurred vision. Do not drive, use machinery, or do any activity blurred vision. Do not drive, use machinery, or do any activity blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you that requires alertness or clear vision until you are sure you that requires alertness or clear vision until you are sure you that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages. can perform such activities safely. Limit alcoholic beverages. can perform such activities safely. Limit alcoholic beverages. can perform such activities safely. Limit alcoholic beverages. Before having surgery, tell your doctor or dentist that you Before having surgery, tell your doctor or dentist that you Before having surgery, tell your doctor or dentist that you Before having surgery, tell your doctor or dentist that you are using this medication. are using this medication. are using this medication. are using this medication. Caution is advised if using this drug in children for muscle Caution is advised if using this drug in children for muscle Caution is advised if using this drug in children for muscle Caution is advised if using this drug in children for muscle spasms, because they may be more sensitive to its possible side spasms, because they may be more sensitive to its possible side spasms, because they may be more sensitive to its possible side spasms, because they may be more sensitive to its possible side effects (such as difficulty breathing or swallowing). See Warning effects (such as difficulty breathing or swallowing). See Warning effects (such as difficulty breathing or swallowing). See Warning effects (such as difficulty breathing or swallowing). See Warning section. Discuss the risks and benefits with the doctor. section. Discuss the risks and benefits with the doctor. section. Discuss the risks and benefits with the doctor. section. Discuss the risks and benefits with the doctor. This medication should be used only if clearly needed during This medication should be used only if clearly needed during This medication should be used only if clearly needed during This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Use pregnancy. Discuss the risks and benefits with your doctor. Use pregnancy. Discuss the risks and benefits with your doctor. Use pregnancy. Discuss the risks and benefits with your doctor. Use for the cosmetic treatment of wrinkles is not recommended during for the cosmetic treatment of wrinkles is not recommended during for the cosmetic treatment of wrinkles is not recommended during for the cosmetic treatment of wrinkles is not recommended during pregnancy. pregnancy. pregnancy. pregnancy. It is not known whether this medication passes into breast It is not known whether this medication passes into breast It is not known whether this medication passes into breast It is not known whether this medication passes into breast milk. Consult your doctor before breast-feeding milk. Consult your doctor before breast-feeding milk. Consult your doctor before breast-feeding milk. Consult your doctor before breast-feeding

Not applicable. This medication is given in a hospital Not applicable. This medication is given in a hospital Not applicable. This medication is given in a hospital Not applicable. This medication is given in a hospital or clinic and will not be stored at home. or clinic and will not be stored at home. or clinic and will not be stored at home. or clinic and will not be stored at home.

Because this medication is given at the site of Because this medication is given at the site of Because this medication is given at the site of Because this medication is given at the site of your condition, most of the side effects occur close to where the your condition, most of the side effects occur close to where the your condition, most of the side effects occur close to where the your condition, most of the side effects occur close to where the medication is injected. Redness, bruising, infection, and pain at medication is injected. Redness, bruising, infection, and pain at medication is injected. Redness, bruising, infection, and pain at medication is injected. Redness, bruising, infection, and pain at the injection site may occur. the injection site may occur. the injection site may occur. the injection site may occur. Dizziness, mild difficulty swallowing, respiratory infections Dizziness, mild difficulty swallowing, respiratory infections Dizziness, mild difficulty swallowing, respiratory infections Dizziness, mild difficulty swallowing, respiratory infections such as cold or flu, pain, nausea, headache, and muscle weakness such as cold or flu, pain, nausea, headache, and muscle weakness such as cold or flu, pain, nausea, headache, and muscle weakness such as cold or flu, pain, nausea, headache, and muscle weakness may occur when this medication is used to relax muscles. Double may occur when this medication is used to relax muscles. Double may occur when this medication is used to relax muscles. Double may occur when this medication is used to relax muscles. Double vision, drooping or swollen eyelid, eye irritation, dry eyes, vision, drooping or swollen eyelid, eye irritation, dry eyes, vision, drooping or swollen eyelid, eye irritation, dry eyes, vision, drooping or swollen eyelid, eye irritation, dry eyes, tearing, reduced blinking, and increased sensitivity to light may tearing, reduced blinking, and increased sensitivity to light may tearing, reduced blinking, and increased sensitivity to light may tearing, reduced blinking, and increased sensitivity to light may also occur. also occur. also occur. also occur. If any of these effects persist or worsen, notify your doctor If any of these effects persist or worsen, notify your doctor If any of these effects persist or worsen, notify your doctor If any of these effects persist or worsen, notify your doctor or pharmacist promptly. You may require protective eye or pharmacist promptly. You may require protective eye or pharmacist promptly. You may require protective eye or pharmacist promptly. You may require protective eye drops/ointments, an eye patch, or other treatment. drops/ointments, an eye patch, or other treatment. drops/ointments, an eye patch, or other treatment. drops/ointments, an eye patch, or other treatment. When this medication is used to prevent migraines, side When this medication is used to prevent migraines, side When this medication is used to prevent migraines, side When this medication is used to prevent migraines, side effects such as headache, neck pain, and drooping eyelid may effects such as headache, neck pain, and drooping eyelid may effects such as headache, neck pain, and drooping eyelid may effects such as headache, neck pain, and drooping eyelid may occur. occur. occur. occur. When this medication is used for excessive sweating, side When this medication is used for excessive sweating, side When this medication is used for excessive sweating, side When this medication is used for excessive sweating, side effects such as non-underarm sweating, respiratory infections effects such as non-underarm sweating, respiratory infections effects such as non-underarm sweating, respiratory infections effects such as non-underarm sweating, respiratory infections such as cold or flu, headache, fever, neck or back pain, and such as cold or flu, headache, fever, neck or back pain, and such as cold or flu, headache, fever, neck or back pain, and such as cold or flu, headache, fever, neck or back pain, and anxiety may occur. anxiety may occur. anxiety may occur. anxiety may occur. If any of these effects persist or worsen, notify your doctor If any of these effects persist or worsen, notify your doctor If any of these effects persist or worsen, notify your doctor If any of these effects persist or worsen, notify your doctor or pharmacist promptly. or pharmacist promptly. or pharmacist promptly. or pharmacist promptly. Remember that your doctor has prescribed this medication Remember that your doctor has prescribed this medication Remember that your doctor has prescribed this medication Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater because he or she has judged that the benefit to you is greater because he or she has judged that the benefit to you is greater because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication than the risk of side effects. Many people using this medication than the risk of side effects. Many people using this medication than the risk of side effects. Many people using this medication do not have serious side effects. do not have serious side effects. do not have serious side effects. do not have serious side effects. A very serious allergic reaction to this drug is unlikely, but A very serious allergic reaction to this drug is unlikely, but A very serious allergic reaction to this drug is unlikely, but A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Symptoms of a serious get medical help right away if it occurs. Symptoms of a serious get medical help right away if it occurs. Symptoms of a serious get medical help right away if it occurs. Symptoms of a serious allergic reaction may include: itching/swelling (especially of allergic reaction may include: itching/swelling (especially of allergic reaction may include: itching/swelling (especially of allergic reaction may include: itching/swelling (especially of the face/tongue/throat), rash, severe dizziness, trouble the face/tongue/throat), rash, severe dizziness, trouble the face/tongue/throat), rash, severe dizziness, trouble the face/tongue/throat), rash, severe dizziness, trouble breathing. breathing. breathing. breathing. This is not a complete list of possible side effects. If you This is not a complete list of possible side effects. If you This is not a complete list of possible side effects. If you This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or notice other effects not listed above, contact your doctor or notice other effects not listed above, contact your doctor or notice other effects not listed above, contact your doctor or pharmacist. pharmacist. pharmacist. pharmacist. In the US - In the US - In the US - In the US - Call your doctor for medical advice about side effects. You Call your doctor for medical advice about side effects. You Call your doctor for medical advice about side effects. You Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. may report side effects to FDA at 1-800-FDA-1088. may report side effects to FDA at 1-800-FDA-1088. may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side In Canada - Call your doctor for medical advice about side In Canada - Call your doctor for medical advice about side In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at effects. You may report side effects to Health Canada at effects. You may report side effects to Health Canada at effects. You may report side effects to Health Canada at 1-866-234-2345. 1-866-234-2345. 1-866-234-2345. 1-866-234-2345.

See also Uses section. See also Uses section. See also Uses section. See also Uses section. This medication can spread to other parts of the body after This medication can spread to other parts of the body after This medication can spread to other parts of the body after This medication can spread to other parts of the body after your injection, causing serious (possibly fatal) side effects. your injection, causing serious (possibly fatal) side effects. your injection, causing serious (possibly fatal) side effects. your injection, causing serious (possibly fatal) side effects. These can occur hours or even weeks after the injection. However, These can occur hours or even weeks after the injection. However, These can occur hours or even weeks after the injection. However, These can occur hours or even weeks after the injection. However, the chances of such serious side effects occurring when this the chances of such serious side effects occurring when this the chances of such serious side effects occurring when this the chances of such serious side effects occurring when this medication is used for migraines or skin conditions such as medication is used for migraines or skin conditions such as medication is used for migraines or skin conditions such as medication is used for migraines or skin conditions such as wrinkles, eye spasm, or excessive sweating are extremely wrinkles, eye spasm, or excessive sweating are extremely wrinkles, eye spasm, or excessive sweating are extremely wrinkles, eye spasm, or excessive sweating are extremely unlikely. unlikely. unlikely. unlikely. Children being treated for muscle spasms have the greatest Children being treated for muscle spasms have the greatest Children being treated for muscle spasms have the greatest Children being treated for muscle spasms have the greatest risk of these effects, as well as anyone that has certain medical risk of these effects, as well as anyone that has certain medical risk of these effects, as well as anyone that has certain medical risk of these effects, as well as anyone that has certain medical conditions (see Precautions section). Discuss the risks and conditions (see Precautions section). Discuss the risks and conditions (see Precautions section). Discuss the risks and conditions (see Precautions section). Discuss the risks and benefits of this medication with your doctor. benefits of this medication with your doctor. benefits of this medication with your doctor. benefits of this medication with your doctor. Seek immediate medical attention if any of these rare but very Seek immediate medical attention if any of these rare but very Seek immediate medical attention if any of these rare but very Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, difficulty breathing, serious side effects occur: chest pain, difficulty breathing, serious side effects occur: chest pain, difficulty breathing, serious side effects occur: chest pain, difficulty breathing, excessive muscle weakness, irregular heartbeat, severe difficulty excessive muscle weakness, irregular heartbeat, severe difficulty excessive muscle weakness, irregular heartbeat, severe difficulty excessive muscle weakness, irregular heartbeat, severe difficulty swallowing or speaking, loss of bladder control. swallowing or speaking, loss of bladder control. swallowing or speaking, loss of bladder control. swallowing or speaking, loss of bladder control.