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Substance abuse and hives

My son is an addict, heroin is the only thing I know of. For 6 months he has had hives. His blood work, intestinal test and allergies test come up negative. When he is going to all these specialist I doubt he is telling them about his drug abuse. Could the hives be caused by the drug abuse?
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Hi a lot of times you will get hives if you are missing your veins while shorting up the junk. I don't mean to sound so blunt but it is very true. Usually it will happen while you are using and go away within a matter of hours. Are they staying on his body all the time? Or coming and going?
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