Who prescribed this combination to you? Both are ssris and combining the two does risk serotonin syndrome or even less than that just too much direct targeting of serotonin. Was this done because you've tried everything and everything has failed so your psychiatrist is looking for out of the box solutions? If you're already taking this combo, is it working or are you suffering odd symptoms? Have you asked your practitioner why he or she is combining two drugs that target the same neurotransmitter? You might not find a lot of Americans who have taken Luvox, it is used but not that much. When it first was approved in Europe, it didn't seek US approval for a long time, so it didn't catch on here as much as other ssris. It also has a lot more adverse drug interactions than other ssris. It was, I think, the first one to get an approval specifically for OCD, but probably not because it works any better for it, just because it was the first to ask for it.