. I am on effexor 225 mg for a month now . Yesterday my doctor upped my dose to 300 mg cz of no to minimal improvement after a month I am also taking seroxat and dogmatil. Do u think the upping my effexor dose my help and kick in ? I am really sick of anxiety and depression . I also have obsessive thoughts . All aspects of my life are affected badly and I feel that it is hard to live this way. Can u plz help me . Thanks a lot I really appreciate it .