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Sertraline side effects

Hello there, I was prescribed sertraline 3 weeks ago today due to venlafaxine not working as it should, iv been on mirtazapine 15mg since December 10th to help with sleep issues, so anyways I stopped 75mg after 4months due to it not working for me and went straight on to sertraline 100mg morning and 15mg mirtazipine at night I felt balanced and levelled out pretty much straight away but today have woke up tired with flu like symptoms is this normal  3 weeks in do I need to stick it out longer for me to get the full benefits or is it that from being ok and doing great then going backwards the sertraline isn't working really don't know what to do as I was only at my docs yesterday saying I was ok and feeling levelled out. Any advice would be appreciated
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