Autoimmune??

[Memoryhelp]

I have been having worsening memory and cognition issues over the past several years along with Fibro type physical symptoms. I am being treated for severe anxiety, emotion dysregulation (related to childhood traumas), depression, an eating disorder, generalized pain, exhaustion and insomnia. My Rheumatologist says my "fog" is too severe for Fibro and referred me to Neuro who ordered a sleep study and MRI. Rheum tests incl Ssdna range 0-200 u/ml w result of 605. ANA screen A range 0-10 Elisa method IgG w result of 36. C3 Complement range 59.0-152.0 mg/dL w result of 171.0. CRP range <1.00 mg/dL w result of 1.12. Rheumatoid factor IgM range 0-25 I.U/ml w result of 33. Rheum says probable Sjögren's but probably not Fibro. I have Factor V Leiden mutation, labile hypertension, my brother has severe sleep apnea and almost died 10 years ago from multiple PEs. My dad had a major stroke when he was 50 but his was from blocked carotid arteries. He continued to suffer TIAs, was then diagnosed with Parkinson's and had related dementia. Drugs never helped Parkinson's symptoms so they think maybe it was something related to Parkinson's. It became progressively more debilitating u til he suffered a fall, fracture and, well you know the rest. I am worried my cognition and memory might have an organic cause besides my psych issues. My brain MRI report says "mild bright FLAIR signal in the peri ventricular and subcortical is present. Not a pattern classic for demyelination but this is non specific. Most likely representing mild microangiopathy changes." Should I get a second opinion or reading? My neurologist is considering this negative but I can't help but believe the severity of my symptoms say otherwise. Help!!

[TheLightSeeker]

Hi Memoryhelp.
I'll do my best!
There are a few things that may connect most if not all your conditions, which seem to be all treated individually and in isolation from each other.
The incompetence of the medical system appalls me,
to put it mildly.
Chronic biological and mental stress from your likely still unresolved childhood traumas, is a huge common denominator!
Does any doctor take the time to consider
the effects of unaddressed stress?
How long before high cortisol levels -the response to stress- can no longer be sustained?
The effects of low cortisol -which is the natural consequence following the prolonged high cortisol levels- are numerous:
Mental and psychological ailments such as depression.
Faintness and dizziness.
Weakness and fatigue.
Heart palpitations.
Emotional hypersensitivity.
Inability to cope with stress.
Social anxiety.
Muscle weakness.
And more!
Do you identify with any of these???
Thought so.
Your multiple conditions developed over time, likely because of hypoadrenalism (low adrenal function- due to chronic unresolved stress)
The adrenals down-regulate thyroid function, an imbalance very delicate to approach in such situations, as this is a survival mechanism, so the higher ranking adrenals force this for their own recovery.
A reputable functional medicine medical doctor, experienced in Holistic Endocrinology, may be able to help you in areas where the damage is not irreversible.
A good therapist who uses regression and hypnotherapy in his/her practice, would be able to help you clear your childhood traumas in just a few sessions.
Talk therapy is OK, but...
You have mineral and nutritional deficiencies, which need to be verified and corrected.
But please beware, many deficiencies remain undetected
due to faulty or wrong tests!
You have become progressively worse in the "care" of
medical professionals and paradoxically you have also developed a dependency to them!
--Don't waste your time and money for another opinion.
There's nothing significant on the MRI report.
--You have some elevated autoimmune markers, which is
expected, due to low thyroid function & de-activated enzymes affecting cellular debris removal , thus causing
autoimmune activity.
--The  Factor V Leiden mutation is not a big factor if heterozygous-only 4x higher risk than normal if inherited
from one parent.
--The labile hypertension is mostly stress induced.
-- There may be genetic mutations you could explore
in order to fine tune your investigation and consequent
treatment plan.
I am familiar with 23andme (online) for genetic testing.
It costs about $200.00 USD for us here in Canada, but I don't know if your State allows this test.
MTHFR gene mutations might be of particular interest to you
(should you have them), as the could not only explain many things relating to your conditions, but also help correct many
issues caused by the mutation(s).

Please note that my suggestions are not a substitute for medical advice.
You may post again with any concerns you have and I will
try to address them to the best of my ability.
Best wishes,
Niko



  

[TheLightSeeker]

Hi Memoryhelp.
I'll do my best!
There are a few things that may connect most if not all your conditions, which seem to be all treated individually and in isolation from each other.
The incompetence of the medical system appalls me,
to put it mildly.
Chronic biological and mental stress from your likely still unresolved childhood traumas, is a huge common denominator!
Does any doctor take the time to consider
the effects of unaddressed stress?
How long before high cortisol levels -the response to stress- can no longer be sustained?
The effects of low cortisol -which is the natural consequence following the prolonged high cortisol levels- are numerous:
Mental and psychological ailments such as depression.
Faintness and dizziness.
Weakness and fatigue.
Heart palpitations.
Emotional hypersensitivity.
Inability to cope with stress.
Social anxiety.
Muscle weakness.
And more!
Do you identify with any of these???
Thought so.
Your multiple conditions developed over time, likely because of hypoadrenalism (low adrenal function- due to chronic unresolved stress)
The adrenals down-regulate thyroid function, an imbalance very delicate to approach in such situations, as this is a survival mechanism, so the higher ranking adrenals force this for their own recovery.
A reputable functional medicine medical doctor, experienced in Holistic Endocrinology, may be able to help you in areas where the damage is not irreversible.
A good therapist who uses regression and hypnotherapy in his/her practice, would be able to help you clear your childhood traumas in just a few sessions.
Talk therapy is OK, but...
You have mineral and nutritional deficiencies, which need to be verified and corrected.
But please beware, many deficiencies remain undetected
due to faulty or wrong tests!
You have become progressively worse in the "care" of
medical professionals and paradoxically you have also developed a dependency to them!
--Don't waste your time and money for another opinion.
There's nothing significant on the MRI report.
--You have some elevated autoimmune markers, which is
expected, due to low thyroid function & de-activated enzymes affecting cellular debris removal , thus causing
autoimmune activity.
--The  Factor V Leiden mutation is not a big factor if heterozygous-only 4x higher risk than normal if inherited
from one parent.
--The labile hypertension is mostly stress induced.
-- There may be genetic mutations you could explore
in order to fine tune your investigation and consequent
treatment plan.
I am familiar with 23andme (online) for genetic testing.
It costs about $200.00 USD for us here in Canada, but I don't know if your State allows this test.
MTHFR gene mutations might be of particular interest to you
(should you have them), as the could not only explain many things relating to your conditions, but also help correct many
issues caused by the mutation(s).

Please note that my suggestions are not a substitute for medical advice.
You may post again with any concerns you have and I will
try to address them to the best of my ability.
Best wishes,
Niko