Hi my dear doctors
My own brother 26 years old software employee who is suffering with viral
fever suddenly got a very major seizure attact and got admitted in hospital on May 10 2019.
There the neurologists prescribed to go through different kinds of scans and blood,urine, serum and even lumbar puncture but all the reports are negative.
Meanwhile my brother is getting seizures again and again so that he got shifted to MICU and they informed that even the antibodies panel is negative and the patient gets persistent seizures then this condition is called auto immune encephalitis.
Due to his condition they started giving him IVIG for 5 days following with different kinds of anti epileptic drugs by taking him on to the ventilator support and along with all these they given large doses of Midazolam, Thiopentone ,and ketamine Cycles.
After all these anti epileptic drugs and sedatives the seizures did not control.
So at last they given retuximab and they observed for two more days and then shifted to normal room from MICU.
After shifting to the normal room he got some minor seizures again but they stopped all the IV injections and started giving oral drugs like levipil 1g, Eptoin 100mg, lacoset 100mg, topomac 100mg, Frisium 20mg, wysolone 10mg, to control seizure attacks.
On 19 July 2019 he was given the second dose of retuximab again and during that time he got a very major seizure which he never had before.
Now the issue is he is using all these medicines as prescribed by the neurologist but from the past two weeks he is again getting one or two minor and major seizures per day.
This I informed to the neurologist and from today they started giving a steroid IV called methyl prednisolone 1gm 1 hour daily for 3days following with weekly once and then after monthly once. But today he again got a mild major seizure.
Myself and my family is very much worried about my brothers condition.So let me know what is this condition called super refractory status epilepticus and auto immune encephalitis.
And how it can be totally cured even if the antibodies panel is negative.
Also tell me whether the treatment undergoing for him is genuine or not.
Note: Because of the treatment given in MICU for about more than a month he had a memory loss too.