Anyone have negative side effects after starting Synthyroid? I’ve been taking the generic Levothyroxine for about 11 yrs and then I went to see an endo for the first time and he switched me to Synthyroid and now I feel horrible. Has anyone else experienced this? My symptoms are all over the place; hungry but then feel sick after eating, burning feeling in hands and feet, tired, dizzy,brain fog,cold hands,hot red feet, just an overall ill feeling. These symptoms started 5 days after starting Synthyroid. Please Help :(