Aa
Aa
A
A
A
Close
Avatar universal

What does this diagnosis mean?

Hi guys!
First time here, wondering if I can get some help about the condition that unfortunately my niece is dealing with. it's called Brain cancer grade 3, but I post the full note below this email under the signature. My questions are: what did the diagnosis find out? What is her survival chance? what is the most effective therapy for her?
Truly appreciate your help,
Mo

Source of specimen: Brain tumor Gross
Examination: SRF consist of multiple irregular fragments creamy & soft tissues TM: 1.5 * 1 * 1 cm.  SOS: M / 1 E:
Total Microscopic Examination: Sections of brain show neoplastic lesion composed of atypical glial cells with large hyperchromatic and pleomorphic nuclei and high mitotic index in fibrillary background with vascular proliferation.  
IHC: CD3: Negative in tumor cells.  
CD20: Negative in tumor cells.  
GFAP: Positive in tumor cells.  
Diagnosis / Impression: DX: Brain tumor, resection:
-Consistent with anaplastic astrocytoma / WHO grade: 3.

1 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Anaplastic astrocytoma is a rare malignant brain tumor which develops from star-shaped cells called astrocytes, which form part of the tissue that protects the nerve cells in the brain and spinal cord. Astrocytomas are classified according to a grading system developed by the World Health Organization (WHO). Grades I or II astrocytomas grow slower and are considered low-grade. Grades III and IV astrocytomas grow faster and are considered high-grade. Anaplastic astrocytomas are grade III.

According to the American Cancer Society, the percentages of patients with an anaplastic astrocytoma who live for 5 years after being diagnosed are:
- 49% for those aged 22 to 44
- 29%  for those aged 45 to 54
- 10%  for those aged 55 to 64
Helpful - 0
Have an Answer?

You are reading content posted in the Brain/Pituitary Tumors Community

Top Cancer Answerers
Avatar universal
Northern, NJ
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Here are 15 ways to help prevent lung cancer.
New cervical cancer screening guidelines change when and how women should be tested for the disease.
They got it all wrong: Why the PSA test is imperative for saving lives from prostate cancer
Everything you wanted to know about colonoscopy but were afraid to ask
A quick primer on the different ways breast cancer can be treated.
Get the facts about this disease that affects more than 240,000 men each year.