I was dx invasive ductal carcinoma Jan 03 - 2 cm with 3/18 positive nodes. Had WLE and total axilliary clearance, 6 x FEC and 25 rads. Have been on Arimidex since Feb 04. For the past 2 months I have had quite severe pain in my left thigh, extending down to my knee. I was discharged by Oncologist Feb 04 and have no contact with the Oncology Dept. Saw my GP 2 weeks ago for the pain and he did alkaline phosphatase blood test - normal. Could this pain be due to the side effects of Arimidex? I am concerned it could be bone mets due to the lymph node involvement. I am seeing him again tomorrow, Sept 6 for further investigation. If I stop Arimidex how does this affect my survival? I am having trouble sleeping as the pain is worse when I lie down. Thank you for such an enlightening forum.