Results and meaning

von4860

Pathology report from breast tissue:  Residual infiltrating lobular carcinoma of breast.  fibroadenoma of breast, fibrocystic changes of breast including fibrosis and apocrine metaplasia, Estrogen and Progesterone positive and HER2/Neu positive.  Predictive marker at 2+ and fluorescence in situ Hybrization fish report not amplified.

Biopsy pathology said:  Insitu and invasiave well differentiated carcinoma with mixed features of ductal and lobular differentiation.

Do the words invasiave mean that it has characteristics to move?  Does one type of feature mean more than another?  What about the words Not amplified?  Her2/Neu Positive?

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Biopsy results

Jupitergsd

Recently underwent stereotactic breast biopsy. Results came back Focal atypical lobular hyperplasia. Referred to general surgeon who was...

Biopsy completed no cancer but

1017Kjdj

benign breast tissue with atrophic changes and fibrosis/fibrocycstic changes- which is fine but what does papillary apocrine hyperplasia ...

My diagnostic mammogram came back as Birads 4 suggesting biopsy

jackdior

I’m 61 and my breast biopsy is tomorrow. Do many of these Birad 4 biopsies come back benign? Really worried..no history of breast cancer ...

Architectural distortion on the screening mammogram and outcome

jjj512

Can anyone share if they had architectural distortion one view on their screening mammogram and the outcome?

Best Answer

bluebutterfly2222

Infiltrating, or invasive, lobular carcinoma means that it has invaded area outside the lobules, as opposed to LCIS (in situ) where it is confined within the lobule and is not actually considered to be cancer, but rather puts the person at greater risk for cancer.

Once cancer has become invasive, it needs to be treated, and further evaluation is usually done to make sure there has not been spread to the axillary lymph nodes or distant sites.

The tumor was determined to be ER+, PR+,and HER2+.

Best wishes...

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bluebutterfly2222

Hi again,

Here is yet another thread that discusses the different tests used to determine HER2 status, esp. when the original test is equivocal...

http://www.medhelp.org/posts/Breast-Cancer/Conflicting-Dako-and-FISH-results/show/547217

bb

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bluebutterfly2222

p.s. Here is a link to additional information about testing for HER2:

http://www.medhelp.org/posts/Breast-Cancer/FISH-technic-for-HER2/show/471142

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