What does "their absence confirms invasion" mean?

[imperialfox13]

I'm reading over my pathology report from my bilateral mastectomy. it says "Additional immunostains are applied, most of which are described in the comment. CD31 on block 2Qdoes not show the area that was suspicious for LVSI on H and E. p63 and SMMGC were done on blocks 2S and 9F, and their absence confirms invasion." What does that mean?  

[Sara_MHModerator]

Hello and welcome to MedHelp's forums.  We know this is a scary time for you.  When you receive a pathology report, it is best to have your results interpreted as they relate to you by your doctor.  They are typically very willing to do this.  Have you met with them yet?  Here is an article that may be helpful to you in the meantime. https://www.cancer.org/treatment/understanding-your-diagnosis/tests/understanding-your-pathology-report/breast-pathology/breast-cancer-pathology.html.

The wording of your report is confusing.  Please let us know what your doctor's interpretation is.  We wish you the very best and look forward to your updates.

[imperialfox13]

This is the first time i have read my pathology report but it is actually 2 years old.  They havent mentioned this at all. Which leads me to believe it isn't concerning to them however i would like it explained further.

[Sara_MHModerator]

I agree with you.  My suggestion is at your next general appointment (routine appointment) that you ask about it.   Then you will have your explanation which I agree is always good to have. best of health to you!