I'm a 60-year old woman, non smoker, 5'2", 109 lbs; occasionally drink a glass of white wine; lifelong exerciser 3-4 days per week. My medications are Lotrel 5/20, Spironolactone 25 mg. (I was on HCTZ, however, it caused me to have a skin reaction from the sun so my doctor switched me to Spironolactone), Simvastatin 10 mg. and Synthroid 50 mcg. Grandmother had angina; sister has CAD partly due to poor lifestyle (very high triglycerides, poor diet, lack of exercise). My doctor gave me a new sophisticated blood test and based on those results he wants to add 150 mg Lipofen to my regimen. Here are those results:
TC 209, LDL-C 101, HDL-C 72, Triglycerides 115, Non-HDL-C 137, Apo B 100, LDL-P 1206, sdLDL 37, %sdLDL 37, Apo A-I 200, HDL-P 50.6, HDL2 17, ApoB:ApoA-I Ratio .50, Lp(a) Mass 15, Lp-PLA 133, NT-proBNP 27, Apolipoprotein E Genotype 3/4, Insulin 3, Free Fatty Acid .37, Glucose 92, Uric Acid 4.6, Homocysteine 8, 25-H Vit D 40, CRP 0.9 .
I'm hesitant to add another drug at this point especially since my triglycerides and HDL are in the optimal range. Do you feel adding Lipofen is the best course of treatment? I would like to trying increasing my Simvastatin dose to 20 mg instead to see if that helps. What would you recommend? Thank you.