Hello and sorry for the late reply.
Chronic hives, also known as urticaria. They usually last for more than six weeks. They are triggered when certain cells (mast cells) release histamine causing rash. Chronic hives can be caused by an immune system (autoimmune) disorder, such as thyroid disease or lupus. Rarely, a reaction to medication, food, food additives, insects, parasites or infection is identified as an underlying cause of chronic hives. It is usually diagnosed by blood tests to detect raised IgE levels, allergy skin tests and tests to rule out the underlying cause for the hives.
Therapy lies in identifying the allergens and avoiding them and antihistamines. Antihistamines can be non sedating or low-sedating antihistamines such as Loratadine or Cetirizine or the nonsedating first-generation antihistamines such as Diphenhydramine or Hydroxyzine. If the symptoms are severe, then steroids are indicated for controlling the symptoms. Others like Omalizumab (Xolair) and Leukotriene modifiers can help to reduce the frequency of episodes.
But in most cases, the cause of chronic hives is never identified, even after testing and monitoring symptoms. Heat, cold, pressure, sunlight or other environmental stimuli may worsen chronic hives. Certain pain medications, such as aspirin, ibuprofen (Advil, Motrin, others) and naproxen sodium (Aleve, Anaprox, others), also can worsen chronic hives.
Hope this helped and do keep us posted.
Hey fransisdlaf . Welcome to the forum.
Hmm. I can only see improvement/resolution, using a bottoms up approach.
So far it's been a merry-go round for you, from symptom to symptom,
back and forth, semi-managed by some medications without much possibility to correct anything and a very compromised immune system.
Allergists and dermatologists in your case just don't go deep enough, as within their specialities they have a certain protocol to follow, so their help is limited and confined to superficial symptom diagnosis & treatment.
Things to check or to rule out:
1. Leaky Gut Syndrome . There's a simple urine test available for Leaky Gut Syndrome: mannito/lactulose test.
2. Highly suspect and possibly linked to #1 are deficiencies.
Tissue minerals analysis, blood work for nutritional deficiencies,
neurotransmitters, electrolytes, test for everything!
3.Intestinal parasites can cause urticaria. Also low grade infectious conditions, candida, metal toxicity, all must be ruled out or addressed.
4. Look into the gut and psychology syndrome (GAPS)
and also the SCD program.
5. Look into Gliadin test (urine), by Cyrex Labs in Phoenix Arizona.
They test 12 forms-not just the alpha ordered by most doctors- of gliadins regarding gluten intolerance (not necessarily only digestive).
Now they can also test which part of the body is affected.
I will leave with this for now and I anticipate you have some questions, so please post again or pm me directly.