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Treatment of liver siderosis

Fourteen months ago, my wife was diagnosed with LIVER SIDEROSIS. Or how to  write that diagnose doctors from Kiev (Ukraine) in the survey conclusion: regenerative (siderotico) nodules, according to the classification LI-RADS-LR2. Destructions indicate the presence of Fe and / or Cu. I didn't get any consultation from our doctors about the medical treatment of the disease, they only offer maintenance treatment and liver transplantation (but the transplant surgery is very expensive for us). Can somebody help me with the following questions: Does anyone ever faced with this disease? whether it is possible to carry out treatment without surgery?
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446474 tn?1446347682
From what I can understand…”Destruction indicate the presence of Fe (iron) and / or Cu (copper) issues.”
From what I can tell it appears that your wife has a  hereditary liver disease. Most likely hemochromatosis (abnormal iron accumulation ) with bronze colored skin) or alpha-1 antitrypsin deficiency which is the absence of this specific enzyme in the liver) or Wilson’s syndrome ((abnormal copper accumulation levels), brown rings around cornea) if it is something to do with copper. There are also a number of other liver diseases it could be. Only a doctor after certain tests would know.

She needs to see a liver specialist as soon as possible to learn if there is some type of treatment to at least slow her liver disease down if possible. It all depends on the cause of her liver disease as to avoiding surgery. Please understand a person can not live without a working liver. That is she needs to know why her liver is failing and if something can be done medically.

Here is some info on LI-RADS. Since she has cirrhosis at minimum she needs to be have surveillance every 6 months.  People with cirrhosis are at higher risk for developing HCC a deadly form of liver cancer if not caught early.

LI-RADS (Liver Imaging Reporting and Data System) is both a set of standardized terminology and a classification system for imaging findings in liver lesions. The LI-RADS score for a liver lesion is an indication of its relative risk for hepatocellular carcinoma (HCC) otherwise known as liver cancer. HCC is  a very deadly cancer if not treated in its early phase. The classification system is meant to be used in livers which have risk factors for HCC (in other words anyone who has cirrhosis and has a cirrhotic liver. HCC rarely occurs in a healthy liver.

The classification is meant to help decrease the variability in interpretation of liver lesions in at-risk patients. Standardization also helps interpret therapeutic performance. The scoring system also potentially helps non-hepatologists interpret the potential suspiciousness of liver lesions in their patients.

LR1 (100% benign) It is not cancer.
LR2 (probably benign)
• Entities are similar to LR1, but the appearance is highly suggestive of the entity instead of 100% diagnostically certain
o atypical appearance of benign entities may be categorized as LR2
o LR2 cirrhosis-associated nodule is also included
LR3 (intermediate probability for HCC)
LR4 (probably HCC)
LR5 (100% definite HCC)
* Does anyone ever faced with this disease?
Many of us. I needed a liver transplant to survive as I also developed HCC along with my cirrhosis.

Whether it is possible to carry out treatment without surgery? No one knows we don't know the cause of her liver disease yet.

Liver transplantation is the only cure for advanced cirrhosis. Some treatments can slow the liver disease so you need to know what liver disease she has and then see what your options are. But usually over time the person’s liver will fail. She needs someone to to help her manage her disease for as long as possible.

Good luck to the both of you.
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