Crohn's diagnosis is not a simple one.
A positive biopsy is not necessary for a Crohn's diagnosis.
They are very useful though as biopsies help confirm what was observed during an endoscopy or other imaging tests.
Usually when other reasonable alternative diagnoses,like C-difficile, E-Coli, Celiac's etc. have been ruled out, then a Crohn's diagnosis can be made.
My position on the approach to diagnose and treat Crohn's
UC, IBD, IBSd or IBSC, (which are challenging to diagnose and treatment is only symptom management ) is that patients like yourself, should also look outside the conventional medical box.
You may want to consider the SCD program, which I know
personally has helped patients (like my own daughter
who had been suffering from chronic symptoms similar to yours- suspected UC ).
It is a rather strict program, and tough to stick to, specially at first, however, it has given back the life to a lot of sufferers.
Do a search for this and if it makes sense to you please post again here or send me a message.
I don't like to exaggerate facts and I have no idea how well you would do on the SCD, but I know it has been a lifesaver for many.
You may have developed some deficiencies along the way,
due to your undiagnosed condition, because of probable
absorption issues. Look into low B vitamins, low magnesium (tissue levels not serum blood levels), low minerals in general,low iron, low thyroid function, low vitamin D, low gastric acid.
Investigating underlying infectious conditions would help explain both the inflammation and the high WBC count.
Beware that sometimes lab tests are not sensitive enough to detect certain pathogens or the pathogens may not be within the blood circulation at the time of testing (inactive phase).
Best wishes,
Niko