I have been contending with debilitating depression the past four years. According to various medical sources, that by engaging in successive pleasure (climaxing/chemical release triggered) does not cause depression. However, in my personal experience this is not the case. To be clear, this is not related to views on both forms of pleasure that lead to guilt, shame, etc. Rather, I likely have an underlying neurological condition that others may possess as well but may be unaware of it or may be convinced otherwise, which furthers possible inadequate consideration of study. As I have come to understand, this may take years to progress when engaging in such pleasures resulting in depression gradually, suffice this underlying condition is present. My basis for this being; I never felt the mental benefits that follow upon climaxing. Rather, given my present predisposition I generally and immediately feel worse, sometimes to the point of being dreadful for a couple of days. Suffice that one were to completely abstain for two weeks I will begin to return to my former state of happiness. This was managed twice recently upon realization that masturbation has been the leading cause. Upon relapsing my depression returns - a very dulled mood with little will and interest in undertaking tasks. I have abstained, yet this time for an unknown reason my genitalia have become very sensitive resulting in climax without ejaculation thus rendering abstinence fruitless. Needless to say, I am uncertain as to the circumstances of my dopamine receptors and or respective neurons. I have pondered possibilities such as receptor damage, obstruction by other neurotransmitters released during climax (if this is possible) and or gradual decreased neuronal activity.
Furthermore, I have been on every standard medication for treatment of depression and am diagnosed with treatment resistant depression. To be clear, shame and guilt have no correlation as I have had no negativity towards engaging in masturbation. I do firmly believe that this unknown condition should be given consideration for study.