OK. So serotonin reuptake is relevant to depression. Then why, during decades of titration and drug switching, were there no tests (blood, brain scans, et. al.) performed on me? If the name of the game was to reduce and/or increase reuptake, how come no “measurement” tests were performed? Do such tests exist? If there is anything to the theory, there is a need to determine OBJECTIVELY, and not merely by implementation of subjective scaling (“Do you ‘feel’ any less depressed?”) whether or not the reuptake has been modified. No scans were ever taken. No blood work was ever performed on me. I was under the care of numerous psychiatrists. All they ever did was say things to the effect of: “Well, let’s try this drug”, “Well let’s try increasing the dosage”. This was not medical science. Science involves measurable, verifiable, objective analysis.