My 16 year old, 11 pound dachshund has ALKP 810, ALT 440, Retics 1.1, HCT 60.2, WBC 3.70, RBC 10.51...which does show early liver disease. She has had bloody diarrhea, possibly from 1/2 2X daily SAMe 225??? It has improved by not giving it to her...I changed her from Fromm Weight Management food to Royal Canin Hepatic; my vet gave her a shot of diathal and put her on endosorb, and the diarrhea is better. I think the dose of SAMe is too high?? And, after breaking the pill, the rest of it cannot be used???