Aa
Aa
A
A
A
Close
1184481 tn?1264398290

low amh level & chances w/IVF

This is my first time ever posting...or joining anywhere for that matter. I was told today that my AMH level is .03, yet we were encouraged to try at least one round of IVF before donor eggs were discussed. I would love to hear any similar scenarios (good or bad) just to know what to expect. I thought I had done ample reading and was well informed about the process, but after today I feel like I have been thrown in the deep end and very overwhelmed. Any clarity of what I am about to take on would help...
56 Responses
Sort by: Helpful Oldest Newest
1002983 tn?1349822086
Hi!!

My AMH is 0.71, and apparently that put me into the range where I would only have a 50% chance of 6 or more eggs in IVF!  I'm 37, and have a son, 4, and daughter 18mths.  I'm trying for baby#3!  I've nearly finished my first ever IVF.  I moved to IVF when I had two failed IUIs.  I had conceived easily with IUI  for my children, so reckoned more IUI wasn't going to work. This IVF, I only produced 6 eggs from 7 follicles, but the reason that happened, my RE told me, is because I was on a higher drug to ensure I didn't ovulate.  I've had problems ovulating early for my IUIs, so the buserelin was kept at a high level to suppress my ovaries.  If I had been on a lower dose, I should have gotten about 12 or so eggs.  What age are you?  And what is your day 2 FSH level and estradiol?  These all figure in too.  What I would say to you, is to go for it, definitely, trying with your own eggs. Even doing just one IVF cycle, with give you an idea of how much ovarian reserve you have left.  If you get enough eggs and even fail, it may work the next time.  Also, remember, having low ovarian reserve does not always go hand in hand with having bad egg quality. I have read of many women on various forums, who have been given all the bad figures and stats by their doctors, but have gone on to have success.  AMH and FSH can only give an idea, it is not 'gospel'.  I think it's great your RE is encouraging you to go for IVF.  He has faith in you.  Definitely go for it!!!  

Good Luck!

Marietta



Helpful - 0
1184481 tn?1264398290
Thank you for the response! Still trying to get a handle on all of the tests, abbreviations, numbers, schedule, etc...so overlook any incorrect labels I might use! My doctor said that he didn't believe I would have success with IUI because of the moderate approach they take with the stimulating drugs (to avoid high number preg.) I am 36 and have never been pregnant & am still waiting to have the FSH test done. After the other bloodwork results and the multiple vag.s-grams, the doctor did not seem optomistic about my ovarian reserve. I am curious why our percentages differ so much - you said you were told 50% for six or more and I was told less than 20% and that he would be suprised by more than 6 (in response to my questions on freezing process). With our funding being limited on how many times I can attempt IVF, I am nervous about the odds being so against us. Thank you for the words of encouragement - somebody has to be "20%" that it worked for! Good luck with your IVF!
Helpful - 0
1002983 tn?1349822086
Hi!!

I think when ovarian reserve gets low, and we're in our late thirties, it's best to bypass the IUI step, and just move up to IVF, as this gives the highest chance.  You are lucky you can get some funding.  Having two children already, I don't qualify for any funding at all, so it's getting really expensive!  Also, where I live, medical insurance doesn't cover anything to do with fertility.  

Do you have the graph showing the AMH levels, with the green, orange and red zone?  If your AMH is .03, then you're in the red zone, but at the top of the red zone.  You know though, all these figures can't be totally relied upon.  I had three IUIs last year - the first IUI was cancelled, because I grew too many follicles.  I was only on minimal puregon, but I still got 10 mature follicles, and multiples was a real risk.  I was given the option of converting to IVF, but I didn't think I needed to go to IVF at that time (silly me)!  Just before I did that IUI, my FSH level was 8.  My next IUI was nearly cancelled due to lots of follicles, but they coasted me for a few days (that means a few days with no meds), and they got me down to two mature follicles.  That IUI failed, I thought because I felt like I ovulated before I even too the HCG trigger (the last injection you take before IUI or IVF, to take the eggs to maturity).  The next IUI, I seemed to be OK, and I grew three mature follicles, and a few smaller ones, but this one failed, and I was sure I ovulated a day and a half after my IUI was performed.  Anyway, after two failed IUIs, I knew this was it, I needed to take this up a step.  Last November, my FSH was done again, and my AMH was also done (I'd never had this tested before).  To my shock, my FSH was 10!!  And my AMH .71!  I couldn't believe my FSH had gotten so bad in just a matter of months, BUT, a doctor on this forum did tell me that FSH levels can show as higher if you have just used fertility drugs, which I had!  Anyway, I'm telling you this, especially about my IUIs, because even though my tests haven't been good, I still did grow good numbers of follicles on low stimulants.  My first IVF has just finished, and I had embryo transfer on the 25th.  I ended up with four fertilised eggs, and one of them was put back on that day.  My clinic changed it's policy a few years ago, and routinely only puts back one embryo if it is of good quality, and the woman has not had more than two failed cycles.  My three other embryos are still being cultured to see if they make it to blastocyst, the stage an embryo is at just before it implants into the uterus wall.  I'm trying to be hopeful, but expecting the worst, as it's only my first IVF.  My chances of conceiving when I did my IUIs were only about 20%, but I still got my babies really easily.  My chances at IVF this time, my RE told me, of actually giving birth as opposed to getting pregnant, are around 20-25% - this isn't high, but he said because my follicles are behaving more like a 40year old, then these are my chances:0(  If I had been a 'normal' 37year old, then my chances would be around 30-35% apparently.  But even though my tests weren't good, they don't really correlate to the follicles I produced, so I think you have to have some hope also.  I think I told you that the reason I only grew seven follicles for this IVF, was due to the fact I was on a much higher dose of buserelin.  This drug was used for me to suppress my ovaries, as I've had trouble ovulating out of time with the protocol.  So in fact, my RE reckons I could have grown around 13, 14 or more follicles.  So I think you have to really keep in mind that they can do all the blood tests in the world, but it doesn't always mean they are right, or that we won't respond well to the stimulants.  I really hope you give it a go with your own eggs.  I'm by no means knocking anyone who has donor eggs - it's wonderful, but just give yourself a go, and see what happens.  Miracles definitely do happen in the world of fertility!!
Helpful - 0
1060308 tn?1295956021
Hi there,

I was wondering if you could help me, ive posted a few questions on here about estradial levels and no-one seems to know what im on about! Ive been having really long cycles and so had blood work done.  The doctors told me that my estradial was 110 and a little low but nothing to worry about and they will check it in three months!! ive researched this and 110 would suggest its really really high!! I rang to double check she said 110 and she definately did but just said its a little low and nothing to worry about! Can you shed anymore light on this please and what estradial relates too please! Im only 25 so hoping its not meaning that i have poor ovarian reserve just yet!!

thanks
Helpful - 0
1002983 tn?1349822086
Gosh, I'm trying to think what mine was.  A couple of years ago, before I conceived my daughter in 2008, my estradiol had risen quite high, and they told me this was a problem because it meant my ovaries were working harder.  I've just had a look at my old notes, and my estradiol (E2) on day 2 was 215.  The clinic told me it should be under 200.  When I conceived my son, back in 2005, it was 160, and I was told this was OK.  The strange thing is that last year, I had my E2 tested (because I'm trying for baby #3), and they told me it was 68!?!  All I know is that it is sometimes suggested that a higher E2 can suppress the true FSH reading (it can make the FSH figure appear lower than it really is).  There are also conflicting studies that say when you're menopausal, your E2 (I think) is low, but then they say that a high E2 is bad!?!  I think a lot of these tests are worthwhile to an extent, but to rely too much on them, and you shouldn't let them put you off fertility treatment.  Looking at what I've got here, I would think you E2 was totally fine, BUT, it could be that the levels are interpreted differently in different countries, and this could be the reason for the discrepency.  I live in New Zealand.    Anyway, don't anyone tell you you have poor ovarian reserve yet just because of some blood tests.  I know of so many women who have had their AMH, FSH figures sky rocket, and they've gotten pregnant!  And if you don't like your clinic or doctors approach, find a place that is good for you!  Get a doctor who is passionate to go on this journey with you.  Good fertility doctors have empathy, and only want their patients to get pregnant:0)

Marietta
Helpful - 0
1060308 tn?1295956021
Hi there,

Thank-you soooo much for your reply! Thats really really helped and given me a really good idea of what it should be! i think from your help that they are probably right and 110 is slightly low!  Ive rang and had my appointment brought forward so will question this face to face at my next appointment.  Im so grateful for you digging your notes out and having a look, i had absolutely no idea what the result meant and every bit of research i was doing through google was throwing different possible ideas at me letting my mind work overtime and worrying me!!!

Thanks once again and i wish you all the best of luck with your IVF.  How far along are you with your IVF?? I think i will end up going through IVF so i may pick your brains some more later on!!

xxx
Helpful - 0
1002983 tn?1349822086
You are so welcome!!!  A good thing to do when you see your doctor is to take a note pad, with all the questions or things you want to talk about, because sometimes it can be overwhelming, and you can forget things.  Doctors are totally fine with this, and often expect it!  

I'm doing my test on Feb 5.  I don't feel confident at all, as I have lots of menstrual like pains, but it is hard to say, as I also had these pains with my two previous pregnancies, and also with my two failed IUIs last year, so it really could go either way.  Whatever, I will probably do another IVF.  I'm also waiting to hear if any of my other embryos got to blastocyst, or got frozen, as that will give me a bit of hope.

For sure be in touch.  It's so comforting having other women going through the same thing.  

Marietta XOX
Helpful - 0
1139097 tn?1271194437
Hi Boudreau,

I noticed you're in SC also.  I was reading your post and I continue to be amazed at the different things women are told in similar situations.  I am 38 yeares old.  In December I got my FSH results of 17.3 and AMH of 0.2.  I was told I had less than a 1% chance of having a biological child even with the most agressive meds and IVF.  I was given those results and the donor egg speech about 3 minutes into the office visit.  (Are you by chance in the Charleston area?  I am and I know of only one Fertility Clinic there.)  I came out devastated and angry at that RE.  I wondered if he was bias towards me due to the fact that I was pursuing single motherhood.  Anyway, I arranged to see a different RE in NC who agreed with the first RE's diagnosis but was much nicer about it and willing to work with me.  I ended up getting pregnant naturally in January.  My "research" lead me to believe that my chances were just as good naturally as they were with ART and I didn't want to skip an opportunity since I was looking at around March to start any actual ART.  I have my first ultrasound on 2/8.  I am continuing under the care of the NC RE at least through my first trimester.
Helpful - 0
Avatar universal
Hi Baby Jazz,

I just read your post and it encouraged me a little. I wanted to sare my story. I just turned 34 and three days ago I received a shocking news of FSH 32, AMH 0.03! I can't believe this can be true, as I have never had these low values. I have been always very disciplined with attending a gynecologist, always checking hormonal status and nobody else before told me that I have a problem and I should not loose time. I should probably tell you that I was pregnant (naturally concieved) 3 years ago and  i lost my baby in a very advanced stage. Ever since, I am fighting with the hormonal values of FSH and E2, but nothing of this type. I am angree at my doctors (SO MANY OF THEM!) and I am at the end of my reproductive age according to these results. Could you or somebody else tell me, have you had any experience with such high values of FSH and extremely (theoretically 0) value of AMH? My ovaries have never been stimulated, nor I have been considered as IVF candidate and now suddenly I am advised to go for egg donor option?!!! How can I accept this? It is fully out my concious, call me selfish or poor, but this I can not absorbe that easily or shall I say not at all!. My husband too.... I am so sad and angry at the same time. My head is killing me for three days in a row, I can not think positively and I have lost every reason for living. Honestly. Nothing makes me happy. I am a doctor btw, coming from a south-east country in Europe where medicine is ok, but not on such an advanced technology level.

I would be grateful of any comments, thoughts and experiences on very high FSH levels, low AMH and biological pregnancy.

THANK YOU!
Helpful - 0
Avatar universal
I just wanted to post a positive story. After 3 miscarriages and a couple of IUI rounds with clomid, my AMH was 0.7. the head of the fertility in london, (best in the uk) told me i would have to do 10 IVF cycles to get a baby. I did two IVF cycles and only had 3 eggs from either of them, and only 1 fertilised egg from each cycle. None of them took.

Very frustrated and sad,  I took 7 months off of all fertility drugs,  detoxed, did acupuncture and got my AMH tested at the end of that period and it went up to 2.4x. Still low but better. I did IVF for a third time, only 2 eggs fertilised but both were top quality and I had a baby girl last May.

Now, two years later, I am 36 and my AMH was just tested and its 6. Still in the low but signficantly better. All the fertility drugs I am convinced make your results even lower.  As an aside, I just saw a specialist here who advised me that for women with low AMH below 2 or 3, he advised TTC naturally rather than doing IVF because the uterine lining gets destroyed by the drugs used in IVF making miscarriages even more likely.  

I would reiterate that this AMH test is so new that doctors advice around the globe differs alot so try your best not to take any doctor's advice as the holy grail. I felt like it was never ever going to happen for me and it finally did. it will happen for you too and i would advise trying naturally or doing IVF (with acupuncture) for as long as you can hack it  before starting down the egg donor route.

Helpful - 0
Avatar universal
I just wanted to post a positive story. After 3 miscarriages and a couple of IUI rounds with clomid, my AMH was 0.7. the head of the fertility in london, (best in the uk) told me i would have to do 10 IVF cycles to get a baby. I did two IVF cycles and only had 3 eggs from either of them, and only 1 fertilised egg from each cycle. None of them took.

Very frustrated and sad,  I took 7 months off of all fertility drugs,  detoxed, did acupuncture and got my AMH tested at the end of that period and it went up to 2.4x. Still low but better. I did IVF for a third time, only 2 eggs fertilised but both were top quality and I had a baby girl last May.

Now, two years later, I am 36 and my AMH was just tested and its 6. Still in the low but signficantly better. All the fertility drugs I am convinced make your results even lower.  As an aside, I just saw a specialist here who advised me that for women with low AMH below 2 or 3, he advised TTC naturally rather than doing IVF because the uterine lining gets destroyed by the drugs used in IVF making miscarriages even more likely.  

I would reiterate that this AMH test is so new that doctors advice around the globe differs alot so try your best not to take any doctor's advice as the holy grail. I felt like it was never ever going to happen for me and it finally did. it will happen for you too and i would advise trying naturally or doing IVF (with acupuncture) for as long as you can hack it  before starting down the egg donor route.

Helpful - 0
Avatar universal
I have been reading all your stories and information on the hard road to get pregnant, we have just gone to a fertility clinic for help because we have been trying for 3yrs to have a second baby. I have just recieved my AMH results and we are devistated they are 0.03. I dont know any of my other results all iv been told was that they were all good and i was nowhere near the menopause !!!! We have been told we "could" try drugs but the outlook is not very good.Is there anyone who has had similar results and had a full term pregnancy.
Helpful - 0
1267764 tn?1302436340
hi, i had an AMH of 0.45. Which devastated me. I'm 31 and no children. I however managed to have 8 follicles and of which they retrieved all 8 and thankfully all 8 turned into embryos. I felt very blessed at that point cuz i was really in the dumps. The key is to superovulate on a high dose. I've done 2 cycles in my first cycle we did the antagonist protocol and that gave me 10 follicles, but we retrieved only 6 and only 3 embryos. But the cycle worked well from a superovulation point of view. That was not a successful cycle for me. I did the 2nd ivf cycle with the short lupron cycle and used a very high dose for superovulation. We used 4 ampules of Menogon and then went up to 8 ampules. I was ready to give up when my scan showed only 6 follicles and the doc then suggested we up my dose. My husband was really the driving force as my doc and I were ready to give up. So try not to worry and discuss both protocols with ur doc and see what will suit u better. Feel free to ask me anything. I did alot of reading online on the different protocols. To understand what was happening. After my first cycles i changed docs also and i think that impacted retrieval and fertilization better.
Helpful - 0
1288187 tn?1271879931
I am 41 yrs old, last friday we got the bad news about my AMH 0.3. Our hopes to become natural parents were gone ... After reading this coments I feel a little better :) , we have to get a second person to carry the baby (surrogate mother) so is more difficult but our hopes still positive!... if anybody in the chat room can give us an advice or recomendations on how to improve my AMH . I was thinking today in acupunture.Did anyone knows or had  expirience positive results? pleasee help me .
Helpful - 0
1130046 tn?1282042404
My fsh was 7 and we were unexplained..one son from our 1st follistim/BD cycle..had low progesterone (4.9)) but upped progestrone and he hung on.now after 2 chemicals ..one from an ivf ...we just got  our amh results and they were a 0.3 ..i was advised not to worry about donor eggs at this point..started DHEA and acupuncture..my RE seemed failry optimistic..(I am 37) that with some changes we have a good shot....we r also going to do oil progesterone and suppositories ..am i crazy for believing him? I am in NY and using a good clinic..i think! We r paying out of pocket and that makes it crazier!
Helpful - 0
Avatar universal
I'm only 28 years old and have been trying to get pregnant for 4 years with 2 miscarriages.  I just found out that I have a FSH level of 18 and my AMH is 0.1!!!  I can't believe that my levels are that bad even though I'm so young.  IVF is probably not an option for us financially.  Is is possible for us to still get pregnant naturally or with meds?  
Helpful - 0
1002983 tn?1349822086
Hi!!

Gosh, it's really hard to say when you'd strike it lucky going naturally, but I guess you could!!  These tests can't dictate 100% how you are likely to respond to drugs or IVF, and I've heard of some women with higher FSH levels than yours who have still been successful.  What you should remember is that these two measures are apparently to do with your ovarian reserve, not necessarily the quality of your remaining eggs.  At 28, your eggs should still be pretty good quality wise, so I would discuss it with your RE if you are seeing one, and see what he recommends.  

All the best:0)
Helpful - 0
Avatar universal
I had 3 miscarriages in 10 months at 5, 6 and 12 weeks. My partner and i went though every available blood test. My AMH came back at 0.8 - we were encouraged to do IVF (not funded) and we got 10 eggs (5 mature) at collection. Although all 10 fertilised, after 48 hrs all but 2 had arrested. We had the best one put back in, a 6 cell with fragmentation. It didnt take and our specialist recommended us to think about an egg donor. My sister had offered which is amazing and we are going to do this later on this year. We are still trying naturally but not falling which is so frustrating after falling 3 x in 10 months. We just wanted to try once more naturally before we do the donor egg. I have absolutely no reservations about having my sister donate but i am so worried that i will still m/c. I guess we will have to work though this and go into it with a positive attitude!
Helpful - 0
1002983 tn?1349822086
That is so disappointing, the miscarriages.  I have two children, 4 and one, but my AMH is now .71, and I'm worried now that even if I do manage to get pregnant, I'll miscarry.  I've never had a miscarriage, but I feel now that my egg quality is a major issue, so I know this is a high possibility.  I'm currently doing my second IVF cycle.  My first one, I only produced 6 eggs, and one 'top' quality 8-cell was replaced, but for whatever reason, it didn't take and the rest of my eggs arrested on development to blastocyst.  I'm hoping to try assisted hatching this time, if I get any suitable embryos.  I'm sure so long as your sister doesn't have any fertility problems, then the chances of you miscarrying with her embryo wouldn't be high.  It is a great idea for your sister to do this!
All the best to you and your journey:0)
Helpful - 0
1354023 tn?1277082767
I had my first appointment with a fertility specialist on June 8th... He said that the ultrasound looked good... my AMH level was 0.7. The nurse said that it was very low but that after the HSG on 6/23 the Dr. wants to proceed with follistim injections. Everything I've read about AMH levels makes me think .7 isn't as hopeless as the drs say. I found a chart that says this is so new and not many studies done but that .7 is LOW NORMAL. (I was suprised because with PCOS I should have had a very high level????)  

I am anxious for wednesday to get here so that I can have the HSG and talk to the dr and nurse about the blood test results. From what I keep reading, it doesn't seem as if there's any indicator... but just try for the best and hope it works.  

Glad that there are places to go to get encouragement and advise... now I just need to learn all the abbreviations! :-)

(I was diagnosed with  PCOS and Hypothyroidism at 19, I'm 37 now. Tried clomid 10 years ago with no reaction.)  
Helpful - 0
Avatar universal
hi , i have just been tested for a p00r amh level 0.14.doc said no chances of getting pregnant .i am 32  ,she said  i would have to look for donar. please suggest if there is any hope for me..can i use my own eggs!!
Helpful - 0
1436280 tn?1283714411
HI EVERYONE!!!!...WELL I AM VERY NEW TO THIS ALL,AND I NEEDED SOME ADVICE.MY HUSBAND AND I ARE NEWLY WEDS,BUT WE'VE BEEN TOGETHER FOR 4 YRS.WE'VE TRYD GETTING PREGNANT FOR ABOUT OVER A YR NOW AND STILL NOTHING,I HAVE IRREGULAR MENSTRUAL CYCLES SO IM THINKING MAYBE IT JUST ISN'T MY TIME YET, OR I DONT KNOW.IM 19YRS OLD SO IM WORRIED THAT IF IM NOT GETTING PREGNANT NOW WHAT WILL THE FUTURE BRING FOR BOTH MYSELF AND MY HUSBAND.WE JUST BAUGHT A HOUSE AND WE WANT TO START A FAMILY,IVE TRYD INFERTILITY PILLS ONE TIME JUST TO REGULATE MY PERIODS AND THEN CLOMIPHINE TO HELP ME OVULATE THE FIRST CYCLE DIDNT WORK.AND I DIDNT WANT TO GET BACK ON THE PILLS AGAIN BECAUSE THEY MADE ME FEEL SICK AND MENTALLY DISTURBED I WAS ALWAYS EMOTIONAL,MOSTLY ANGRY.WICH IS NOT LIKE MYSELF...WELL TO MAKE A LONG STORY SEEM  SHORT WE ARE LOOKING INTO IVF WE HAVE A CONSULTATION THIS MONTH SEP 20TH,SO PLEASE IF ANYONE WILL SPARE ME SOME ADVICE...

GOODLUCK TO YOU ALL
Helpful - 0
1346146 tn?1299360497
I am 36. My amh was .7.  We did a medicated cycle with timed intercouse.  We did follistim, novarel, estrace, and progesterone and the first cycle worked.  I am now 15w4d pg.  Even with low amh it can still happen with a little help, good luck to you all.
Helpful - 0
1346146 tn?1299360497
We also did femara.  
Helpful - 0
Have an Answer?

You are reading content posted in the Fertility and Trying to Conceive Community

Top Trying to Conceive Answerers
5875562 tn?1410898886
miami, FL
4769306 tn?1568490209
NC
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Many couples are turning to acupuncture to treat infertility. But does it work? We take a closer look.
Does exercise really lower fertility? We take a look at 8 common myths about fertility.
Your guide to safely exercising throughout your 40 weeks.
Learn which foods aren't safe to eat when you're eating for two.
Is your biological clock sounding the alarm? Dr. Elaine Brown explains new advances in egg freezing.
A list of national and international resources and hotlines to help connect you to needed health and medical services.