I have been taking one form or another of prilosec/protonex, etc, over the past several years. I have what would be considered the typical symtoms of acid reflux. Especially, if I would eat anything spicy a couple of hours or so before bedtime I would supplement my prilosec with a zantac. In any event, the acid reflux has been with me for several years. A couple of months ago, I went in for a routine check up, and had my bloodtest, which showed a slightly elevated ALP of 85. I am planning on going back to get another blood test soon, however, wanted to share with the group that I started taking Milk Thistle about three weeks ago to see whether this might help lower my enzyme levels to normal. What I have been finding is that I no longer need to take the prilosec or zantac, there is something (or appears to be something) in the Milk Thistle that is both helping me feel better as well as well as lowering my need for prilosec or other antacids. My question is, has anyone else tried Milk Thistle and has it helped their acid reflux? Also, any observations as to why this seemingly is working, and that I do not need nearly as much of the Prilosec or zantac product is occurring, are welcome. Thanks in advance for your comments.