Btw, medhelp seriously needs some rework with their sign-up process. Here I am a fairly honest whiste-blower and darn it! I had to try three email addresses (all fake) and three fake id's, before I could login to post. Guh! However, please note, what I'm SAYING isn't a lie and it's so darn easy to verify - just google or do a 'whois' lookup for vescell.com and check up with the US government's Edgar database (http://www.sec.gov/edgar/searchedgar/webusers.htm) Also: http://www.msnbc.msn.com/id/36849354/ns/health-heart_health
You need to ask yourself what a TheraVitae is doing with an ex-coffee marketing company - and one assumes that they were honest souls who were peddling coffee and not something else.
All registered companies have to file things with Edgar and there are websites that mirror this information, which Google indexes and makes available to common-folk. This is the link i got:
Item 1.01 Entry into a Material Definitive Agreement
On July 16, 2008, RegenoCELL Therapeutics, Inc., formerly Good Buddy’s Coffee Express, Inc., a Florida corporation (“ RCT ” or the “Company”) completed actions necessary to change its business strategy from opening drive through cafes which will offer clientele during the morning commute coffee and pastries within one minute after cash is received from the customer to a new stem cell therapy business opportunity as set forth in a Letter of Intent dated March 31, 2008 with TheraVitae, Inc. (the “Stem Cell Business”). These actions included the filing of Amended Articles of Incorporation which among other matters changed the name of the corporation to RegenoCELL Therapeutics, Inc. and increased its authorized capitalization to 600,000,000 shares, approved Amended Bylaws, issued restricted common shares, par value $.0001 per share, to Douglas T. Rice (250,000), Domenic Mazza (5,000,000) and James F. Mongiardo (15,000,000), ratified the March 31 Letter of Intent with TheraVitae, and approved the Employment Agreement with James F. Mongiardo as President and Chief Executive Officer.
The Letter of Intent with TheraVitae provides for a non exclusive license in Mexico and later the Islands of the Caribbean to commercialize TheraVitae’s stem cell therapy for cardiovascular indications. The Company may establish clinics to treat congestive heart failure patients with VesCell, TheraVitae’s stem cell therapy. It also provides for an exclusive license in the United States, Canada and Mexico to obtain regulatory approvals and then market VesCell stem cell therapy for the treatment of peripheral artery disease.
As part of the change in strategy to the Stem Cell Business as further described below under Item 5.02, Scott Massey, the former President, Chief Executive Officer and Director of the Company, and Phillips N. Dee, the former Director of the Company resigned from their positions as officers and directors of the Company and James F. Mongiardo was elected as Chief Executive Officer, President, Treasurer, Secretary and sole Director of the Company.
Oh! and those blogs and websites that you see when you Google, that tout stem cell research.. most of them are fraudulent. Think about it!! It costs like 40$ to buy your own domain (eg: my-fake-domain-to-peddle-crap.com) and web-space. Then it's just a matter of putting up all sorts of crap. If these guys are screwing patients for 60KUSD and their initial investment is 40USDx10 (10 websites) not to mention all the free web-hosting offered by google/yahoo/blogspot etc.. well.. quite a profitable business! They don't even bother to fake their whois information (whois info is info YOU provide when you buy a web-domain eg: crap.com) No wonder Theravitae (VesCell) is registered in Thailand and uses gmail (free email hosting) for their technical contact. Jeeze! What cheap-skates! Email: mryetun AT gmail . com (I spaced that because medhelp clobbers emails *grumble*). Do a WHOIS to figure out who owns a domain AND this information can be faked so.. it's shocking that these con-bstrds aren't even bothering to do this!! Ooo and look at this:
Domain Name: VESCELL.COM
Reseller..............: #1 Cheap Domains
Created on............: 11 Oct 2004 14:03:19 EST
Expires on............: 11 Oct 2014 00:03:16 EST
Record last updated on: 23 Aug 2005 12:03:09 EST
*snicker* Cheap Domains, as their reseller! Compare this vs microsoft.com - nice and studly..
Admin Name........... Administrator .
Admin Address........ One Microsoft Way
Admin Address........ Redmond
Admin Address........ 98052
Admin Address........ WA
Admin Address........ UNITED STATES
Admin Email.......... ***@****
Admin Phone.......... +1.4258828080
Tech Name............ Hostmaster .
Tech Address......... One Microsoft Way
Tech Address......... Redmond
Tech Address......... 98052
Tech Address......... WA
Tech Address......... UNITED STATES
Tech Email........... ***@****
Tech Phone........... +1.4258828080
If you are uncomfortable with medical claims, I suggest you just ignore the company, simple as that.
I believe someone was arrested in the UK or Europe recently after being sued for giving hope regarding stem cell usage to heart patients. Nothing worked with any of his patients and he is not struck off the medical register. I think the law should be tightened regarding claims about medicines and therapies, there are a lot of desperate/vulnerable people out there.
I didn't read it all but there's so much information given I was beginning to think it was a spam message. Say they hate it but then offer a lot of information for us to look it up ourselves. I almost reported it but didn't in case it was legit.
Hi, I'm very comfortable with medical claims both false and true, because I'm not desperate for a cure. Those posts were meant to inform patients that there are ways to verify the antecedents of a company touting the latest cure. I'm not saying that the stem cell business (as a whole) is fraudulent!! All I'm saying is that NOT ALL stem cell companies are honest in their intent and it behooves us to be careful and diligent in our research. Edgar and WHOIS are FREE tools that help us gather information before shelling out 60K-USD.
As for your suggestion that I "ignore the company" that may be into shady practices..
1.Mathematically speaking, that doesn't work. Eg: "Poison reverse" is a concept that computer networks use to tackle false information. You can Wikipedia that BUT in short it works by permitting a network router to tackle false routing information by actively transmitting correct information vs staying silent. They tried the keep quite routine and it didn't work out..
2. This forum(Medhelp) wouldn't exist if everyone took your advice. After all, taking beta blockers for heart disease is also a medical claim. Patients here discuss a variety of medical claims and decide what claims to trust.. some take beta blockers and some take ACE.. some take both. I don't think very many people on medhelp stay at home like little church mice.. Or to put it more bluntly.. umm.. in a not-unfriendly manner.. You don't seem to be taking your own advice, darn it!
@ed34: yup :), google Susan Watts(she's awesome and cute), BBC and stem cell. They nailed some stinkers in South Africa (Laura Brown - ex-model, ex-Dr.Trossel and Stephen Van Rooyen). Here's the link:
Mind you I'm all for stem cell cures - I just want to know who's doing it and what his degrees are and which college he passed out of (and I'd check up on all that info) and who his partners are, and what his wife does for a living etc etc..
Here's some more useful information from EDGAR. This is taken from FORM 8-K,
July 16 2008, REGENOCELL THERAPEUTCS, INC. Formerly Good Buddy's Coffee
With respect to the Letter of Intent, TheraVitae is the owner of certain proprietary technology and rights for an angiogenic cell precursor-based product (VesCell#) covered by trade secret and patent applications, actions or continuations; more specifically, November 24, 2004 United States Patent Application 11/271,043; June 1, 2005 United States Number 60/576,266; 60/588,520; PCT/IL2005/000571; December 14, 2005 United States Number 60/636,391; 60/668,739; PCT/IL2005/001345; December 14, 2005 United States Number 60/668,739; 60/636,391; PCT/IL2005/001348; May 31, 2006 United States Number 60/687,115; PCT/IL2006/000633; and March 8, 2006 United States Number 60/780,781, Provisional Application. TheraVitae and/or its affiliates presently treat patients in Bangkok, Thailand and other locations with VesCell# for cardiovascular and other indications such as peripheral artery disease. Pursuant to the grant of a non exclusive license for congestive heart failure and exclusive license for peripheral artery disease, the Letter of Intent provides that the Company will pay TheraVitae upon closing its first and subsequent financings as a license fee of twenty-five percent (25%) of the proceeds of each financing to a maximum of $1,000,000.
So I checked USPTO (patent office) and what do you know! PCT/IL2005/000571,
relies on provisional patents ("In an embodiment, techniques described herein are practiced in combination with (a) techniques described in one or more of the references cited herein, (b) techniques described in U.S. Provisional Patent Application 60/576,266, filed Jun. 1, 2004, and/or (c) techniques described in U.S. Provisional Patent Application 60/588,520, filed Jul. 15, 2004. Both of these provisional patent applications are assigned to the assignee of the present patent application and are incorporated herein by reference.")
and the guys that applied for it are:
Applicants: IN MOTION INVESTMENT, LTD.; Basement, Kwong Loong Tai Building, 1016-8 Tai Nam West Street, Laichikok, Kowloon (All Except US).
FULGA, Valentin [IL/IL]; (IL) (US Only).
PORAT, Yael [IL/IL]; (IL) (US Only).
BELKIN, Danny [DE/IL]; (IL) (US Only).
SHIMONI-ZALK, Daphna [CA/IL]; (IL) (US Only).
POROZOV, Svetlana [RU/IL]; (IL) (US Only).
Inventors: FULGA, Valentin; (IL).
PORAT, Yael; (IL).
BELKIN, Danny; (IL).
SHIMONI-ZALK, Daphna; (IL).
POROZOV, Svetlana; (IL
TheraVitae is not mentioned as an Applicant for PCT/IL2005/000571! In fact their
filings with SEC are kind of skimpy - just a mailing address, since it looks to
be registered in Canada.. what I did get was this:
By: /s/ David M. Reese
Name: David M. Reese
Title/Date: President and CEO 4/02/08
And an address in Canada:
1273 HILLVIEW CRESCENT
ONTARIO A6 L6H 2C6
I'll have to check more carefully with SEDAR (the canuck equivalent of EDGAR)
but I couldn't find much about TheraVitae in canada that was official..
As for their patents.. I haven't had time to look at all of them! BUT Hey! Hey!
Now YOU guys actually know what sekret orange juice is being peddled :) You
could take those patent docs(go to USPTO and dl those patents - IL is an israeli patent so Israel-PTO for that) to a doctor or research scientist in the US and ask
them for an opinion.. My opinion (as a layman) is kind of simple. I took a look
at one patent and this is what it says:
Treatments such as HMG CoA reductase inhibitors (statins) have also been reported to elevate numbers of EPCs in circulation.
culturing the second-pass cells in a culture medium including at least one of the following: erythropoietin, VEGF, IGF, FGF, a molecule from the estrogen family (e.g., 17-#-estradiol, estrone, estriol, an estradiol derivative, estradiol valerate, estradiol cypionate, mestranol, quinestrol), a molecule from the progestin-family (e.g., progesterone, hydroxyprogesterone caroate, medroxyprogesterone acetate), a statin (e.g. Simvastatin, Atorvastatin), and an antidiabetic agent (e.g., Rosiglitazone).
In an embodiment, the antidiabetic agent includes Rosiglitazone, and culturing the second-pass cells includes culturing the second-pass cells in a culture medium including Rosiglitazone.
In an embodiment, the statin includes Simvastatin or Atorvastatin, and culturing the second-pass cells includes culturing the second-pass cells in a culture medium including Simvastatin or Atorvastatin.
In an embodiment, hormone molecules from the estrogen and progestin families include 17-#-estradiol and progesterone, and culturing the second-pass cells includes culturing the second-pass cells in a culture medium including 17-#-estradiol and/or progesterone.
Now if you have been following the news.. Atorvastatin was found to increase myocyte regeneration in cardiomyopathy patients (myogenesis).. ergo.. :) maybe all you doofuses need to do is take some statin pills :) be careful though! Statins are contra-indicated in cardiomyopathy - rhabdomyolysis.
Oh well, I'm pooped. You might want to EDGAR search "Kwalata Trading" :) apparently there was some falling out between the Israelis and TheraVitae
"Item 8.01 Other Events
On February 10, 2010, Kwalata Trading Limited, a wholly owned subsidiary of TheraVitae, Inc., a Canadian corporation, obtained an ex parte order from the District Court for the Central Region of Israel to seize the intellectual property alleged owned by Kwalata which is in the possession of either Theravitae, Ltd. or Regenocell Laboratories Ltd., the wholly owned Israeli subsidiary corporation of the Company. The Court appointed trustee took files and computers including computers dedicated solely to equipment from Regenocell Laboratories facilities at 7, Pinchas St., Ness Ziona in what the Company considered to be an unlawful attempt to close the facilities.
And someone here owes me pizza and some orange juice - not the stem cell type :) If you mutton-heads can drop 60KUSD or 30KUSD even, for what looks to be high dosage statin therapy :) but I won't swear to that.. get it checked by a scientist - mail someone in Stanford working on heart stem cells.. Sorry for the really long posts.. but at least I substantiate my claims somewhat.. so don't get all huffy.
err.. correction.. falling out between Regenocyte+TheraVitae and Kwalata (Israeli).. or something like that..
Checked the patent database - couldn't find a single patent actually issued to any of their names (Porat, Porozov, Fulga). Links:
Israel PTO: http://www.ilpatsearch.justice.gov.il/UI/MainPage.aspx
Canada PTO: http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/search/advanced.html
What they have done is apply for patents, which is different from actually having a patent issued. Provisional patent application 60/636391 is dated (priority date) 14 Dec 2004 and 60/668739 is dated 5 April 2005, Applicant: MOTION INVESTMENT Ltd, PCT/IL/2005/001345(I used Canada PTO).
Provisional patent applications have a lifespan of 1 year - and this is not a "standard application" - it has no enforceable rights and you have to apply for a standard patent application within said 1 year; It auto-expires if you don't file within a year.
In short, I could apply for multiple patents, fill my provisional application with utter rot, and run around telling everybody that I have "patents pending" - very good for marketing and self-promotion. Wonder why the USPTO and CPTO and IPTO thought it not fit to give them a patent.. the IPTO says that their provisional application: "Current Status: Application Abandoned"
Yael Porat (now CEO of BioGenCell, from her CV):
"company's strategic planning. Dr. Porat, an author of many scientific publications and patents, holds MA and PhD degrees in Immunology from the Sackler School of Medicine, Tel-Aviv University, Israel.
Legally, i think anyone could just "borrow" from their patent and see what the heck they were injecting into people.. The funny thing is, the current study by Aastrom Biosciences
has as it's lead investigator, Dr. Amit Patel who seems to be involved in this Thai venture.
on the other hand
"Atorvastatin was found to increase myocyte regeneration in cardiomyopathy patients"
Well that would cause some pretty life threatening situations if true because it is being realised HDL turn myocytes into macrophages, into which LDL fills them with Fat. Then the HDL steals proteins off the macrophages so the fat is trapped inside, disabling the ability for further HDL to remove the fats, causing it to become a foam cell, a very angry nasty atherosclerosis causing cell. If this has been shown by atorvastatin etc, then I wonder why a health warning hasn't been issued. Better to cut your losses and run now, rather than face millions of law suits for ignoring evidence.
You're seem like a neurotic, obsessive-compulsive, gutless parrot.
You're not thinking critically, merely reporting bits of stuff that makes no difference to real patients like me. That's right, since my treatment with Theravitae's product Vescell in Thailand for ischemic cardiomyopathy in April 2010, my heart and scar tissue has shrunk in size, my EF has risen by 60%, and my PVC's have dropped from a detectable 34,000 per month to an undetectable 2,000 pm. Consequently, for the first time in 17 years, I have no symptoms of breathlessness or fatigue and I look well according to me and others. I'm also back to full time work. Quality of life = amazing, now.
Your defensiveness strikes me as fear. You don't want to believe that Tharavitae's product works because you don't want others to get better, since you don't have the guts to try. I think you have psychological problems as well as heart problems. Not surprised, since both work well together. Get your fears/resistance sorted out first then open your heart to the possibility of an improved life by trying the treatment. Pun intended.
You should be focused on establishing knowledge of the treatment methods and associated world-class reputations of the medical and the laboratory personnel and not the red tape stuff of forming company's. But that would be too confronting for a coward I suppose, so I forgive you...