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sotolol vs propanolol

My cardiologist currently has me taking 80mg sotolol twice a day for pac's/pvc's. I still have a few pac's/pvc's daily but not like before. Some days are worse then others but of all the medicine he has tried me on this seems to work the best. However, I have been having frequent migraines. I was on propanolol 120mg for about a year. Never had one migraine. He wants me to quit taking the sotolol and go back on the propanolol. The propanolol didn't seem to do much for the pac's/pvc's.  I hate taking meds at all. I currently have a loop recorder in my chest recording all my heart beat activity. Everytime I have an episode he can see what it is. Of course he says it's nothing and I need to learn to deal with it. I've had every heart test imaginable everything is normal. I'm getting this recorder out in two weeks. The sotolol helps but I've noticed everytime I have a skipped or extra beat I get so sick in my stomach for about an hour. Is that a side effect of the medicine? Never noticed that with propanolol but had episodes of Pac's/pvc's of every other beat or so for 3-5 hours at a time. Talked to my pharmacist and he said to take which ever one I feel better with. DUH! Only thing don't overlap the medicines. I need to make sure there's at least 12 hours between quiting one and starting the other.  I don't know what to do, any suggestions would be greatly appreciated........
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612551 tn?1450022175
Sotolol is a Class III anti-arrhythmic medication and is very powerful, hence, may people can't take it because they suffer from side effects.  I think only Amiodarone is stronger.  

As you have noted it works better than propanolol, a beta blocker, but the head aches too much in my view, I'd quit taking sotolol.
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1124887 tn?1313754891
Yes, Sotalol is a beta blocker (class II) with a class III antiarrhythmic ability.

I strongly doubt my doctor would treat PACs or PVCs with Sotalol, except if the premature beats triggered other and more severe arrhythmias like A-fib or ventricular tachycardia (by the way, if the PVCs trigger ventricular tachycardia, Sotalol may worsen the problem) but I doubt this is what you're experiencing.

Propranolol is a known treatment to migraines. Sotalol is not. It has something to do with how the beta blockers solve in water or fat. Sotalol only solve in water.

When do the PACs and PVCs appear? With high heart rate or low heart rate? If they essentially appear with low heart rate, beta blockers usually don't work.

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Avatar universal
I notice the pac's and pvc's when I'm just relaxing watching tv, working on my computer. Alot of times they wake me up in the middle of the night. I thought the sotalol was a little extreme to. Especially when the doctor says they are nothing to worry about. He said I'm to aware of what my heart is doing. I got another migraine attack last night and it's really weird, I was watching tv got up to go to bed an I could feel my heart beat pounding in my head, neck and ears. Almost like I couldn't hear anything clearly then the aura started and I knew it was coming. Now this morning I have this extemely bad headache on the left side of my head. I've had a headache since the 2nd of January and three migraine attacks.
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Avatar universal
I would quit the sotalol.
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