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Best Treatment for HBv

I am 53 years old last month I have went for preventive health check up and based on the report findings the followings noted; SGOT 83 IU/L ,SGPT 200 IU/L , Doctor recmended me to see the Gastro.consultant , the gastro.consultant advised me to go for others test the result are as follows: Anti-dsDNA 16.6 IU/ml. , HBsAg test value 9520(Reactive) ,HCV,IgG test value 0.12 ( non Reactive) ,Anti Nuclear Antibody ( ANA) 0.12 , Immunoglobulin IgA 279 mg/dl , Tissue Transglutaminase antibody IgA 0.40 U/mL , Anti Mitochondrial Antibody , Serum 0.26 UL/ml , ASMA 2.70 U/mL , LKM Antibody 0.02 U/ml , Hepatitis B envelope Antibody test value (Ab) 43.0 ( Reactive) , Hapatitis Be Antigen ( HBeAg) 0.15 ( Non reactive),AFP 4.38ng/ml  , HBV DNA Quantitative,Real Time PCR 5156250 IU/ml. Based on this the Doctor advised me for the treatment  Tab.Entavir 0.5 mg one daily. Here i went for second opinion with Lever specialist consultant and he advised me to go for Fibroscan which the result is 5.91 Kpa ( Negative for fibrosis).Now the lever specialist advised for Viraferon Peg 80 mg once in a week and monitor CBC & S creatin every 15 days.I have not started the treatment yet as I am going out of India for 1.5 months as Doctor told me that this treatment will be given under there supervision , please suggest which treatment is suitable under these report.Also with vaccine this problem will be solved and how long i have to take this treatment.
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Avatar universal
only if hbsag goes less than 1500iu/ml peginterferon add on before 3 years of antiviral makes sense
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Avatar universal
Hi Stef

Please find the previous report:
AST 83 IU/L dated 7/11/13 , AST 48 U/L dated 27/1/2014.
ALT 200 IU /L dated 7/11/2013 , ALT106 U/L dated 27/1/2014
HBsAg : 9250 ( Interpretation of test result ( Vitros ECi) dated 9/11/2013
HBsAg serum ( CMIA ) : 7767.68 IU/mL dated 28/1/2014
HBV DNA : Quantitative ,Real Time PCR : 5156250 IU/mL dated 10/12/2013.
Fibroscan: 5.91 Kpa
Genotype : not tested.

Doctor advised me for Viraferon Peg 80 mg once a week.
Ttreatment not started yet.
Please suggest the best option.

Thank you,
Helpful - 0
Avatar universal
Hi Stef

Few more test report , please note:
HBe Ab : 43.0 dated 6/12/2013 .
HBeAg : 0.15 dated 6/12/2013.
AFP: 4.38 ng/mL dated 5/12/2013.
Anti-dsDNA result : 16.6 IU/mL dated 13/11/2013.HCV,IgG 0.12 dated 9/11/2013.
Anti Nuclear Antibody ( ANA) 0.12.IgA : 279 mg/dL dated 9/11/2013.
AMA : 0.26 UI/mL dated 11/11/2013.
ASMA : 2.70 U/ml dated 13/11/2013.LKM 0.02 U/ml dated 11/11/2013.

Thank you,
Helpful - 0
Avatar universal
both hbsag and hbvdna too high for pegintf to respond, you may try 24 weeks and then go for tenofovir

i myself would go for:
tenofovir plus telbivudine 1 year and then discontinue telbivudine and add on peg to tdf

or tdf 3 years
tdf+pegintf 2 years
Helpful - 0
Avatar universal
Thank you so much Stef2011 , tomorrow i will discuss with Doctor and go for the best option . Shall up date you .

Thanks for your kind suggestion.
Helpful - 0
Avatar universal
Hi Stef

Hope you are doing good ,
Today I consulted my Doctor and discussed the report , he suggest me to go for TERAVIR 300 Mg one daily.
Also ask me to repeat the blood test after one month for CBC , LFT & S.creatinine.
Please guide me the treatment is okay.

Thank you,
Helpful - 0
Avatar universal
very good choice
Helpful - 0
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