Aa
Aa
A
A
A
Close
Avatar universal

Best Treatment for HBv

I am 53 years old last month I have went for preventive health check up and based on the report findings the followings noted; SGOT 83 IU/L ,SGPT 200 IU/L , Doctor recmended me to see the Gastro.consultant , the gastro.consultant advised me to go for others test the result are as follows: Anti-dsDNA 16.6 IU/ml. , HBsAg test value 9520(Reactive) ,HCV,IgG test value 0.12 ( non Reactive) ,Anti Nuclear Antibody ( ANA) 0.12 , Immunoglobulin IgA 279 mg/dl , Tissue Transglutaminase antibody IgA 0.40 U/mL , Anti Mitochondrial Antibody , Serum 0.26 UL/ml , ASMA 2.70 U/mL , LKM Antibody 0.02 U/ml , Hepatitis B envelope Antibody test value (Ab) 43.0 ( Reactive) , Hapatitis Be Antigen ( HBeAg) 0.15 ( Non reactive),AFP 4.38ng/ml  , HBV DNA Quantitative,Real Time PCR 5156250 IU/ml. Based on this the Doctor advised me for the treatment  Tab.Entavir 0.5 mg one daily. Here i went for second opinion with Lever specialist consultant and he advised me to go for Fibroscan which the result is 5.91 Kpa ( Negative for fibrosis).Now the lever specialist advised for Viraferon Peg 80 mg once in a week and monitor CBC & S creatin every 15 days.I have not started the treatment yet as I am going out of India for 1.5 months as Doctor told me that this treatment will be given under there supervision , please suggest which treatment is suitable under these report.Also with vaccine this problem will be solved and how long i have to take this treatment.
Best Answer
Avatar universal
only if hbsag goes less than 1500iu/ml peginterferon add on before 3 years of antiviral makes sense
170 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Hi Stef
As advised by the Doctor to go for blood test after one month of teravir 300mg. So today i have done the test , please find the report as below:

LEVER PANEL1:LFT,SERUM:
1. AST - 48 U/L.
2. ALT - 111 U/L.
3. GGTP 35 U/L.
4. ALKALINE PHOSPHATASE ( ALP) - 184 U/L.
5.BILIRUBIN TOTAL 0.52 MG/DL.
6. BILIRUBIN DIRECT 0.10 MG/DL.
7. BILIRUBIN INDIRECT 0.42 MG/DL.
8. TOTAL PROTIEN 7.20 G/DL.
9. ALBUMIN 4.20 G/DL
10.A: G RATIO 1.40.

COMPLETE BLOOD COUNT ( CBC) :
11. HEMOGLOBIN 17.40 G/DL.
12.PACKED CELL VOLUME (PCV) 51.80%
13. BC COUNT 5.67 MILL/MM3.
14. MCV 91.20 FL.
15.MCH 30.60 PG.
16. MCHC 33.60G/DL
17.RED CELL DISTRIBUTION WIDTH (RDW) 13.80%
18. TOTAL LEUKOCYTE COUNT ( TLC) 7.80 THOU/MM3.

DIFFERENTIAL LEUCOCYTE COUNT (DLC)
19.SEGMENTED NEUTROPHILS 59.10%.
20 LYMPHOCYTES 31.80%.
21. MONOCYTES 6.30%
22. EOSINOPHILS 2.30 %
23. BASOPHILS 0.50%.

ABSOLUTE LEUCOCYTE COUNT
24.NEUTROPHILS 4.61 THOU/MM3
25. LYMPHOCYTES 2.48 THOU/MM3
26. MONOCYTES 0.49 THOU/MM3
27. EOSINOPHILS 0.18 THOU/MM3
28. BASOPHILS 0.04 THOU/MM3

CREATININE,SERUM 0.94 MG/DL.
Please review and suggest , I am taking one tablet daily TERAVIR 300 MG.

Thank you
Helpful - 0
Avatar universal
all those tests are useless to define response to tdf or response to an hbv infection, is the doctor a liver specialist?

you can save creatinine test as baseline, this is needed every 6 months at least
hbsag quant in iu/ml
hbvdna in iu/ml
hbeag/hbeab
hbv genotype

have those tests as soon as possible because you need it as baseline
Helpful - 0
Avatar universal
Hey Steff if  if hbsag goes less than 1500iu/ml how long of a course of Peg Interferon is needed to clear the virus?
Helpful - 0
Avatar universal
There is no answer to your question. Hbsag movements is solely dependend on your immune system - virus relationship. Your Hbsag can drop by thousands within one month as well as it may take year to clear hundreds of hbsag. Nobody will tell how you will react to interferon unless you try yourself and see.  
Helpful - 0
Avatar universal
Hi Stef
I have done HBSag & Hbvdna in the month of Jan.2014 and the results are as follows: HbSag - 7767.68 iu/ml ( CMIA) dated 28/1/2014.
HBV DNA - 5156250 iu/ml.
Hbeag -0.15.
HbeAB - 43.

Doctor is liver specialist in well known hospital in India.
He started treatment based on these test but he asked me to repeat some test after one month of treatment , the tests are - CBC , LFT & S.creatine. which i did & sent the result to you. I have not shown these result to Doctor as yet.
Helpful - 0
Avatar universal
Hi jcm

Are you visiting ILBS in Delhi
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis B Community

Didn't find the answer you were looking for?
Ask a question
Popular Resources
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
Can I get HIV from surfaces, like toilet seats?