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Best Treatment for HBv

I am 53 years old last month I have went for preventive health check up and based on the report findings the followings noted; SGOT 83 IU/L ,SGPT 200 IU/L , Doctor recmended me to see the Gastro.consultant , the gastro.consultant advised me to go for others test the result are as follows: Anti-dsDNA 16.6 IU/ml. , HBsAg test value 9520(Reactive) ,HCV,IgG test value 0.12 ( non Reactive) ,Anti Nuclear Antibody ( ANA) 0.12 , Immunoglobulin IgA 279 mg/dl , Tissue Transglutaminase antibody IgA 0.40 U/mL , Anti Mitochondrial Antibody , Serum 0.26 UL/ml , ASMA 2.70 U/mL , LKM Antibody 0.02 U/ml , Hepatitis B envelope Antibody test value (Ab) 43.0 ( Reactive) , Hapatitis Be Antigen ( HBeAg) 0.15 ( Non reactive),AFP 4.38ng/ml  , HBV DNA Quantitative,Real Time PCR 5156250 IU/ml. Based on this the Doctor advised me for the treatment  Tab.Entavir 0.5 mg one daily. Here i went for second opinion with Lever specialist consultant and he advised me to go for Fibroscan which the result is 5.91 Kpa ( Negative for fibrosis).Now the lever specialist advised for Viraferon Peg 80 mg once in a week and monitor CBC & S creatin every 15 days.I have not started the treatment yet as I am going out of India for 1.5 months as Doctor told me that this treatment will be given under there supervision , please suggest which treatment is suitable under these report.Also with vaccine this problem will be solved and how long i have to take this treatment.
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Avatar universal
only if hbsag goes less than 1500iu/ml peginterferon add on before 3 years of antiviral makes sense
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Avatar universal
Hi Stef
Hope you are doing good ,
As I discussed earlier post that my Dr.Endocrinology recommended to stop Vit.D3 supplement for some time due to elevated level of Serum Clcium and 24 hors urine - calcium & Phosphorus. Today I did the test and the result are as follows:Calcium, Serum:

Date 8 .8. 2015: Calcium serum: 10.40 mg/dL

- on 23 Feb.2015: 10.60 mg/dL ( Ref.range 8.8 - 10.60)
-on 7 March 2015: 10.50 mg/dL .
-on 3 April 2015: 10.50 mg/dL.
- on 1 may 2015: 11.20 mg/dL.    
-On 10 may 2015: 9.6mg/dl.      
-On 13/6/2015 : 9.8 mg/dl.

24 hours urine test result:
Date 8.8.2015: 303mg/day ( Ref.range 100-300 )
- 156/6/2015 : 375 mg/day.

Phosphorus,24-Hour Urine :
Date 8.8.2105 : 737.3 mg/day ( Ref.range 400-1300)
- 15.6.2015 : 825 mg/day.


Vitamin D,25 Hydroxy:
- on 8 Nov.2013 : Vitamin D , 25 - Hydroxy ,Serum ( CLIA ) 41.05 nmol/L.
- on 22 June 2014Vitd25oh :18.22 ng/ml.
- on 24/8/2014 : 51 ng/ml.
- on 8 Nov.2014 : 51.2 ng/ml.
- on 5 Feb.2015 : 157.55 nmol/L ( Sufficient range 75-250 nmol/L )
- on 7 march 2015 : 164.50 nmol/L (CLIA method) Range 75-250 sufficient)
- on 3 April 2015: 174.12 nmol/L ( CLIA method - Ref.renge 75-250 sufficient )
- on 1 May 2015 : 65.2 ng/ml
- On 13/6/2015: 41.1ng/ml
- On 8/8/2015: 26.01 ng/ml ( Insufficient range)

PTH ( Parathyroid Hormone) Intact, Serum :
- on 5 Feb.2015 : 73 pg/mL ( Ref.Interval 14 - 72 )
-on 7 March 2015: 86.60 pg/mL ( CLIA method Ref.range 14-72 )
-on 3 April 2015: 73.60 pg/mL.
- On 1 May 2015: 83.80 pg/mL.
-On 13/6/15: 63.45 pg/ml.
-On 8/8/2015: 95.40 pg/mL. ( HIGH)

S.Creatinine:
-On  10 May 2015: S.creatinine : 1.4 mg/dl.
-On 13/6/2015: S.creatinine : 1.09 mg/dl (HIGH)
-On 8/8/2015: 1.00 mg/dL

L.F.T.-

- 28 Jan.2014
SGOT / AST 48 U/L.
SGPT / ALT - 106 U/L.
ALK . Phosphatase - 139 U/L.

L.F.T.-
-  27/4/2014-
SGOT / AST 40 U/L.
SGPT / ALT  65 U/L.
Alkaline Phosphatase ( ALP ) 143 U/L.

L.F.T :
9 August 2014:

Serum billrubin total ( Jendrassik- Grof) 0.8 mg/dl ,
Serum Billrubin direct ( Jendrassik - Grof) 0.1 mg/dl,
Serum Billirubin Indirect 0.70 mg/dl ,
AST/SGOT ( kinetic-Henry) 10 IU/L  ,
ALT / SGPT ( kinetic-Henry) 26 IU/L ,
Serum Alkaline Phosphatase ( Kinetic) 110 IU/L ,
GGT 22 IU/L , S.total Protein ( Bluret) 7.3g/dl ,
S.Albumin 4.1 g/dL ,
S.Globulin 3.20g/dL ,
A\G Ratio 1.28.

L.F.T
- on 8 Nov.2014:
Serum Biluirubin indirect 0.50 mg/dl ,
AST/SGPT ( kinetic - Henry) 24 IU/L. ,
ALT/SGPT ( Kinetic Henry) 34 IU/L. ,
Serum Alkaline Phosphatase ( Kinetic) 136 * High  IU/L. ,
GGT 17 IU/L. ,
S.total protein 7.8 g/dl. ,
S.Albumin 4.1 g/dl. ,
S.Globulin 3.70*High g/dl ,
A\G Ratio 1.11* Low.

LFT: On 25Jan.2015:
SGOT/AST:  12.8IU/L ( Ref.range 0.0 -37.0)
SGPT/ALT : 24.7 IU/L ( Ref.range 0-41 )

LFT : On 20 Fe.2015:
ALT : 26 IU/L ( Ref.Range 10-40)
Serum Alkaline Phosphatase 112* High IU/L ( Ref.Range 32-92)
GGT : 21 IU/L ( Ref.Range 7- 64)

LFT On 13/6/2015:
ALT 32 IU/L.
AST 19 IU/L.
Serum Alkaline Phosphatase 104 IU/L ( HIGH)
A|G ratio 1.34 (LOW)
GGT 17 IU/L.

LFT on 8/8/2015:
AST: 22 U/L.
ALT: 30 U/L.
GGTP: 22 U/L.
Alkaline Phosphatase ( ALP): 143 U/L.
Phosphorus: 2.00 mg/dL.

On todays report I noticed that my Vit D3 declining and PTH increasing , also I noted that my ALP always on high side and Phosphorus on LOW side.
I have not taken vit D3 supplement almost 6 weeks now, i will consult Doctor soon and ask him about the Vit D3 as well as PTH.
Looks like my calcium both on serum and 24 hours urine in line with the reference range.
Please look into all these test report and suggest ,

Thank you,
Helpful - 0
Avatar universal
Dont worry you are perfectly healthy, you can wait for hbsag to becone lower on its own and use peginterfero  to clear hbsag when it reaches less than 1000iu ml

check hbvdna, liver function, fibroscan every year.if hbvdna becomes elevated or fibroscan start tenofovir
ulrasound evry 6 months
hbsag quantevery year

eat fresh and organic, no smoke, take vit d3 supplements 5000 to 10.000u daily
Helpful - 0
Avatar universal
Hello Stef Sir...
Last year during blood donation in dec 2014 i found out dat i am hbsag +ve.
I went to the drs in delhi but hvnt got satisfactory answers.Right now i feel normal but i am worried about my future.
M not married and i have left alcohol an year back.
my reports are...

1.HBV DNA -            not detected , initially in dec 2014 - 40 Iu/ml

2.Hbsag QUANT.-     now 8126, initially in dec 2014 - 14070 Iu/ml

3.fibroscan-              5.4 kpa

4.alpha feto protein-  2.79 ng/ml

5.ALT-                     44 now

6.HbeAg -                -ve

7.anti Hbe -             +ve

8.Ultrasound -          Normal

9.Total protein -         8.1

10.Mean normal prothrombin time - 11.10

11.Prothrombin ratio - 1.11

12.Anti HAV -           +VE

MY QUESTIONS ARE-

1. If i was infected recently or since childhood.My brother is Hbsag -ve.

2. I am 24 years old now.Can you please tell how many years approximately I will live.

3. I am non alcoholic.I smoke 1-2 ciggs max.

4. what food shuld i eat,any specific kind or anything with less fat and hygenic.

5. In wat interval i need to go for the tests.
6.Do i need to worry much.I mean can i live d way i was before.

Please help sir.
Since i have came to knw this I am not able to live fully.I have became anxious,depressive and not happy at all.
Ur valuable suggestions can help me.
PLEASE HAVE AN EYE OVER THE ISSUE SIR.
Helpful - 0
Avatar universal
I was looking for clues on vit d toxicity and found this info about people supersensitive to vit d despite low levels, from their hypothesis/experience it is an unbalance with vit A fro cod liver oil.carlson is a brand with vit a from cod liver oil at doses of 10.000iu or 25.000iu.it is good with bottles with monthly pill supply, the big supply bottle has soy that can be gmo so avoid it

http://www.westonaprice.org/blogs/cmasterjohn/is-vitamin-d-safe-still-depends-on-vitamins-a-and-k-testimonials-and-a-human-study/

Try and let us know if vit a makes calcium normal by fe weeks
Helpful - 0
Avatar universal
Thank you so much ,
Helpful - 0
Avatar universal
http://www.sanihelp.it/esami/118/calciuria.html

tests are not bad, all normal, only urine calcium is high, check that page and try to translate from italian, there are many diseases making high calcium and your doctor should have checked them all because one thing we know for sure there is something wrong with pth, calcium and vit d

Helpful - 0
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