Can HBV be cleared, not just controlled, NOW?

[cajim]

Here (http://www.medhelp.org/personal_pages/user/900408) are posted pre- and post-treatment labs of some HBV patients with different levels of severity, all cured with HBsAg becoming negative!

What do you think?  Are you still satisfied with the brain washing that "HBV is not curable", "Treatment can only control the replication of HBV", "There is no cure now", "Live with it", "Disease is part of life"?

Note:

1.  Top lab sheet is pre-treatment; bottom lab sheet is post-treatment.
2.
HBsAg = HBsAg
抗-HBS = HBsAB
HBeAg = HBeAg
抗-HBe = HBeAB
抗-HBc = HBcAB
HBV-DNA = HBV-DNA

[hepa114]

Can you elaborate more? you are clamming H-B can we cured by using ramdev’s medicine, what is the authenticity of your statement? Did you tested these medicine on yourself or on someone you know or just heard about this? Please post the lab test results before and after treatment. Also explain more about the treatment? What kind of medicine he give? Do they have any scientific proof?

[stef2011]

hbv can be eradicated (hbsag negative and hbsab>1000miu/ml) by interferon+antivirals as a member who did this combo just posted
in this forum i will probably be the next to make this combo if i don t clear within 2011, this combo is not used often but it has the highest clear rates

[LilHope2010]

Hepatitis b can be cure by Ramdev's medicines

[shellywinters]

I do hope there is a way that you can get your VD3 levels up, the latest research shows how crucial it is just to keep people without our condition healthy. Its a vitamin that is crucial to human health. That is why its the only vitamin human can synthesize on their own with sun exposure.

[stef2011]

i am not taking anymore because it damaged kidneys, 4-5000iu daily from january and vit D still low, so i disconitnue and creatinine is back normal, i will take little sun even if it didn t work eather

i have already posted all studies of immune modulation and trails about vit D and hbv and hcv but it can damage kidneys so i stopped it

all vitamins, zinc, selenimum are kept optimum ranges by diet, at the end of this month i should already be out of 12kpa so no need to change anything, it is all a matter of balance not too much and not too little but the main thing is hbvdna und, alt<20 and possibly hbsag reduction which equals to immune system response increase

[shellywinters]

Vitamin D is extreemly important I hope you looking to taking it. I have gathered some medical journals from the US National Institute of Health. It says alot that you are un aware of the benifits of Vitamin D when cirrohsis is present. Also please look into the selenium AND ALpha Lipoic acid. It will further reduce your finrosis regression.

I do wish you the best.

http://www.ncbi.nlm.nih.gov/pubmed/17222588
Clin Gastroenterol Hepatol. 2007 Apr;5(4):513-20. Epub 2007 Jan 10.
Vitamin D and parathyroid hormone in outpatients with noncholestatic chronic liver disease.
Fisher L, Fisher A.
Department of Gastroenterology, Canberra Hospital, ACT, Australia. ***@****
Abstract
BACKGROUND & AIMS: The liver plays a central role in vitamin D metabolism. Our aim was to determine the prevalence and type of vitamin D-parathyroid hormone (PTH) disturbance in ambulatory patients with noncholestatic chronic liver disease (CLD) and its relationship with disease severity and liver function.
METHODS: We studied 100 consecutive outpatients (63 men, 37 women; mean age, 49.0 +/- 12.1 [SD] y) with noncholestatic CLD caused by alcohol (n = 40), hepatitis C (n = 38), hepatitis B (n = 12), autoimmune hepatitis (n = 4), hemochromatosis (n = 4), and nonalcoholic steatohepatitis (n = 2); 51 patients had cirrhosis. Serum concentrations of 25-hydroxyvitamin D (25[OH]D), PTH, calcium, phosphate, magnesium, creatinine, and liver function tests were determined.
RESULTS: Serum 25(OH)D levels were inadequate in 91 patients: vitamin D deficiency (6.8 pmol/L) was present in 16 patients. The prevalence of vitamin D deficiency was significantly higher in cirrhotic vs noncirrhotic patients (86.3% vs 49.0%; P = .0001). In Child-Pugh class C patients, 25(OH)D levels were significantly lower than in class A patients (22.7 +/- 10.0 nmol/L vs 45.8 +/- 16.8 nmol/L; P < .001). Serum 25(OH)D independently correlated with international normalized ratio (negatively; P = .018) and serum albumin (positively; P = .007). Serum 25(OH)D levels of less than 25 nmol/L predicted coagulopathy, hyperbilirubinemia, hypoalbuminemia, increased alkaline phosphatase, and anemia and thrombocytopenia.
CONCLUSIONS: Vitamin D inadequacy is common in noncholestatic CLD and correlates with disease severity, but secondary hyperparathyroidism is relatively infrequent. Management of CLD should include assessment of vitamin D status in all patients and replacement when necessary.




http://www.ncbi.nlm.nih.gov/pubmed/73950
Absorption, hydroxylation, and excretion of vitamin D3 in primary biliary cirrhosis.
Krawitt EL, Grundman MJ, Mawer EB.
Abstract
Oral vitamin D3 was poorly absorbed by 4 out of 6 patients with primary biliary cirrhosis; absorption was negatively correlated with faecal fat excretion. 25-hydroxylation of vitamin D3 given by mouth or intravenously was not impaired in the patients compared with controls of similar vitamin-D nutritional status. Urinary radioactivity derived from the intravenous dose of vitamin D3 was significantly greater in patients than in controls and was positively correlated with the serum-bilirubin concentration. Excretion in the urine may lead to loss of administered and endogenous vitamin D and thus contribute to vitamin-D deficiency in patients with primary biliary cirrhosis.

http://www.ncbi.nlm.nih.gov/pubmed/18290722
J Bone Miner Res. 2007 Dec;22 Suppl 2:V50-4.
Vitamin D insufficiency/deficiency in gastrointestinal disorders.
Bikle DD.
Department of Medicine, Veterans Affairs Medical Center, University of California, San Francisco, California, USA.
Abstract
Vitamin D and calcium are critical for skeletal health. Their absorption from the intestine is negatively impacted by a number of gastrointestinal diseases and surgical procedures, leading to osteoporosis and/or osteomalacia. Diseases of the liver can impact the metabolism of vitamin D to its circulating form, 25(OH)D, as well as the production of carrier proteins, albumin and vitamin D-binding protein, that may alter the delivery of 25(OH)D and its active metabolite 1,25(OH)(2)D to target tissues, including the skeleton, again leading to bone disease. The clinician evaluating a patient with apparent osteoporosis and vitamin D deficiency/ insufficiency needs to consider a gastrointestinal etiology. Similarly, the clinician evaluating a patient with a gastrointestinal disorder needs to evaluate that patient for vitamin D deficiency and bone disease. Treatment involves adequate vitamin D and calcium supplementation to achieve normal serum 25(OH)D, PTH, and serum and urine calcium levels.
PMID: 18290722 [PubMed - indexed for MEDLINE]

[stef2011]

i am spreading this because i haven t seen anybody here reaching the result of decreasing hbsag fast, and to tell you the truth this will be my last post talking to you, i really don t like the way you speak and also the little scientific knowledge of hbv illness you have, i am sure i have studies much more than you

[stef2011]

well my success story is hbsag decresing hbvdna und and finrosis regression from 16.3 to 13.9 in less than a year (12kpa is the cirrhosis cutoff), of coruse followed by one the most expert researcher in the world about hbv (not a doctor), what should i use chemical vitamins for since i have a balanced diet and normal level except vit D but there is nothing to make it normal (sun or megadoses)

[shellywinters]

You seem very "know it all" and yet you mentioned in another post that vitamins were useless when in fact they are extremely important in the protection of the liver against oxidative damage.  I have read many of your posts and I give you credit for knowing a great deal but certainly not all.

You keep shutting down phyllanthus but have you tried it? If so which species? It makes a big difference. How frequently did you use it? IT makes sense to say that “it might have worked for you only that much, it makes no sense to say if it worked for me it is proof it will work to others”

This forum is the place to relate success stories and the treatment used. Its up to the reader to decide what is right for them With that said, phyllanthus has bee repeated scientifically studied and research and chances are it will work for all of people. My opinion is that when take correctly as I have recommended it will work. Taken with the multivitamins containing 400 IU of Vitamin E, 2,000 IU of Vitamin D 200 micro grams of Selenium and 200 grams of Alpha Lipoic acid and viral load will come down as will liver enzymes regardless of Chronic or non chronic status.

I know I tend to sound harsh in my replies so I say to you it is not my intention to undermine your integrity nor your valuable influence here. Keep in mind you do have influence here as I see a lot of you comments, your relies to questions and helpful suggestions. Remember you are influencing others opinions and ideas that may influence their health negatively or positively.

[hbv]

it's paid :(

[hbv]

Research on Phyllanthus niruri: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6R-4SDX2XS-2&_user=10&_coverDate=12%2F15%2F2008&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_searchStrId=1488874883&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=c7d01916f9c351863110ee2b307b6012&searchtype=a

[ono8ono]

what you said:
The power of interest groups: if Hep B can be so easily cured, who are there to buy the tons of ADV, ETV, TDF, etc.? who are there to pay to visit the western doctors? who are there to sell all they have and then borrow a lot to pay surgeons for liver transplantation and all the procedures associated with the surgery for 1-year-or-so's additional living, in poverty and agony?

I totally agreed! Just follow the money; big phar are in for big profit only; they don't care about the cure! cure mean no more incoming stream of profit!! No more business! It is not just phar, think about all the companies making all the test tubes, bottles, equipment, needles etc etc; they all depends on NO cure!  

[stef2011]

you have to consider we are not all the same, nitazoxanide cleared hbsag from 25% of 8 hbe negative patients by 1 year and from 3 hbe pos in 2 years but i'd never say ntz clears hbsag, i'd say it might because what works for one person doesn t work for all

the same for tenofovir, entecavir they clear hbsag on about 5-8%, not from all

same thing from phyllanthus it might have wroked for you only that much, it makes no sense to say if it worked for me it is proof it will work to others.we might try it and see in combo

it is also very important to know if you were hbe positive or negative because phyllanthus niuri and urinaria have different activities, i don t remember which one but one of the two works on hbe pos but not on hbe neg

[shellywinters]

I have the results and tried to post them but PDF was the only format I could get the copy machine at work to send the scan out to.


1st one says 1-7-2009
  Hepatitis B Virus PCR 10,400,000
HBV RNA LOG 10                          7.02

2nd 3-6-2009
Hepatitis B Virus PCR  358,000
HBV RNA LOG 10                       5.55

3rd 7-30-2010

Hepatitis B Virus PCR     254
HBV RNA LOG 10                  2.40

I had a test in April 2010 that was 1,200.
That was at the Liver specialist at UCLA medical center in Westwood
That is the test that shows I am still not making the antibodies to clear this.
He did not give me the RNA Log number via e-mail with the VL#.

I am requested those results via e-mail from the Doctor but he is out till OCt 10th

I have never heard them mention anything about fibrosis and I was always told according to enzyme levels, my liver is in perfect health. I have only had elevated enzyme levels once in Aug of 2008 before I found out about HB and that was why they wanted to test for HB/C & A.  I was sick and went in for blood work and forgot to mention all the Tylenol and hard core pain killers I took to rid the sever body aches from the flue that week prior. All blood tests prior even when I was in ICU for heart issues, they never detected liver abnormalities.

[shellywinters]

I soooo cant wait for my results to be faxed in!!!!

from over Ten Million down to only 252 in a year. 97% of the reduction happend in 2 months thanks to the Chanca Piedra!

[shellywinters]

Antioxidant Therapy. As with other diseases related to inflammation and tissue damage, oxidative stress is a key mediator that continues and magnifies the ongoing disease process. The livers of people who have hepatitis show reduced levels of antioxidants, which are consumed in an effort to protect the liver. According to a report in the June 1998 issue of the Journal of Clinical Gastroenterology, investigators showed that nutritional antioxidants are potential therapeutic agents for diseases such as hepatitis. Other investigators reported at the same time that oxidative stress (free-radical damage) is often seen in hepatitis B and may contribute to the emergence of hepatocellular carcinoma, seen in patients after years of chronic liver inflammation. The study stated that antioxidants that down-regulate oxidative damage may be a useful complement to specific antiviral drugs in the therapy of viral diseases.
In a related study, vitamin E (alpha-tocopherol) was reported in a randomized, double-blind, placebo-controlled study to be a successful adjunct approach when combined with alpha-interferon therapy in the treatment of hepatitis because of its strong antioxidant activity (von Herbay A et al 1997).
Selenium. The protective role of selenium against HBV was reported in 1997 in the journal Biological Trace Element Research. The study reported that, in areas of China with high rates of hepatitis B and primary liver cancer, high levels of dietary selenium reduced the incidence of liver cancer and hepatitis B infection. In a 4-year trial of 130,471 people, those who were given selenium-spiked table salt showed a 35.1 percent reduction in primary liver cancer, compared with the group who received salt without selenium. In the same journal report, another clinical study of 226 people who tested positive for hepatitis B showed that taking a 200-mcg tablet a day of selenium reduced the incidence of primary liver cancer to zero. Upon cessation of selenium supplementation, the incidence of primary liver cancer began to rise. The study seems to indicate that taking selenium on a continuous basis is beneficial to people who have viral hepatitis (Yu SY et al 1997).
These human trials have been duplicated in animal studies. The animal studies showed that selenium supplementation reduced hepatitis B infection by 77.2 percent and precancerous liver lesions by 75.8 percent.
Another study in the Journal of Trace Elements and Medical Biology reported the role of trace minerals in diseases such as liver disease and hepatitis. The report indicates that, while there is still some debate regarding the specific role of trace minerals, minerals such as selenium and zinc are of benefit to those who have diseases such as hepatitis (Loguercio C et al 1997).
A 3-year study of 20,847 people investigated whether supplementation with sodium selenite could prevent hepatitis B. The researchers concluded that: "The incidence of virus hepatitis infection in the test population was significantly lower than that of controls provided with no selenium" (Yu SY et al 1989).

[cajim]

WHAT IS THE TREATMENT this thread is talking about. Is it the phyllantus amarus?

--No.  It is a layman-style Chinese medicine whose 11 months course I went through.  Details here:

http://www.medhelp.org/posts/Hepatitis-B/How-I-manage-my-HBV/show/1337595

[shellywinters]

I guess I'll have to share lab results.

1/6/09 Over 10 Million, 3/06/09 300 thousand

1/10/10 1,230 and then 8/06 only 252

Never took meds, just a bunch of herbs, teas, vitamins/minerals and amino acids. I refused to except I could not get rid of this as I am considered chronic and my body could not clear it on its own.

oh and to Stefen, phyllantus nuri works better also known as Chanca Piedra

My doctor said anything under 29 is considered negative and I fully expect to receive a negative test result by the New Year!

I guess what it really comes down to is what you believe. If you really buy into you are going to have it for the rest of your life then you will, you wont even research other ways to clear this. The first challenge is opening your mind to the possibility that you can. The perception that herbs and other natural remedies are not sufficient is formed by the lack of availability of data easily accessible showing its effectiveness and that may be no accident.


I spent what seems like a lifetime researching natural remedies for HB. I tried them all! Chinese herbs, Amazonian teas, Japanese mushrooms, sugar reduced and raw veggie increased diets.

If you look in the right places you will find medical journals where research, tests and studies have been done with the above mentioned methods. It workded.

[stefen143]

i have viewed this very long post which tackles mostly regarding the debate between the eastern alternative medicine vs the conventional western medicine.

i am just at lost through the discussions; which left me asking WHAT IS THE TREATMENT this thread is talking about. Is it the phyllantus amarus?

[cajim]

1.  As patients, we can only hope our doctors are wise, knowledgeable, and caring.  Let us hope his statements of "get me HBsAg negative" and "HBeAg(-) and HBeAb(+), the loss of DNA to UND, could potentially avoid a flare in future" are based on facts.

2.  What is his reason for switching to LAM?  Cost?

3.  Are you still going to try Dr. Thyagarajan's treatment?  If yes, it would be helpful to others to keep a detailed record of your experience.

Best wishes.

[bram44]

Before going on treatment this is one question I asked my doctor. I feel ok now and my family is not affected with me. So why can't I be monitored, instead of going on treatment.

He mentioned, I have not so high viral load and a year of treatment should get me HBsAg negative (yes he said negative). I did show him www.hepb.org guidelines and various drug results, which put the changes between 5-10%.

He said HBeAg(-) and HBeAb(+), the loss of DNA to UND, could potentially avoid a flare in future. He also mentioned given my geno type is "A" - he will monitor and switch to LAM when the DNA is going up in future. His plan was to knock of the virus count and monitor it for future. He said potentially (theoretically) I may have to be on meds, but practically I could off of it in a year.

Though it was not convincing, I took this route. I am not confident - but hopeful.

[cajim]

"I am on Tenofavir treatment now, after 3 months will get myself tested for change in viral load etc... Then I will start this (of course need to inform my doctor). May be I will stop viral treatment and start this."

--3 months of  Tenofavir needs to reduce viral load to UND to be considered effective.  After that if you decide to stop Tenofavir, you need to be very careful about flares.  Also if you started out with HBeAg(-) then there is no clear end point for Tenofavir.  How confident are you of the ability of this treatment to continue to suppress viral load or get rid of the virus?

[cajim]

From the autobiography of Dr. Baruch Blumberg:

Plant studies
In the late 1980s another project began to dominate the research in our laboratory. Would it be possible to devise a therapy for the millions of patients with HBV including many of the approximately 375 million HBV carriers in the world? The concept of rationale design for drug discovery was (and is) in vogue at this time; it is an approach that is based on a molecular understanding of the disease process and the identification of biochemical or biophysical processes of disease at which a medication could be designed to interfere to abort or eliminate the disease. However, most drugs in use have been derived from already existing "natural" chemicals found in plants or other biological material. I decided to look for a medication in the plants that had been used in indigenous medical systems – folk medicine – to see if any of these contained constituents that were anti-viral. My colleagues and I consulted the many texts on folk uses and made a list of all the plants that had been used to treat yellow jaundice, the most obvious symptom of hepatitis. Jaundice can be the result of many diseases, for example, hemoglobinopathies, but probably the most common cause worldwide would be viral, including HBV infection. This resulted in a list of over a thousand plant species. I then sorted the list by the country where the folk medicine was used and identified plant genera that were used on three or more continents or geographic regions. This decreased the number of candidate plants and we finally chose a small weedy plant, Phyllanthus amarus for further study. Phyllanthus species were widely used in India, China, elsewhere in Asia, South and North America, Africa, and in the Pacific for the folk treatment of jaundice. It was also selected because P.S. Venkateswaran, the natural products chemist in our laboratory had known of this plant in his youth. There were also other plants on the short list with which a more limited series of studies were done.

During the next five years or so we collected many of these plants in their native habitat. This resulted in some interesting field trips. I had already engaged in many trips during our research on the distribution of polymorphic traits and in the HBV studies. But this was different. Medical field research is usually done indoors, observing patients in hospitals and populations in villages, towns, and cities. Collecting plants meant that one was outdoors, in the field, forest and jungle; and I enjoyed that very much. There were collecting trips to India (including a fascinating few days in the jungles of the Western Ghats in Karnataka), Nepal (including a long trek in the Himalayas ), England, France, Ireland, Korea, Singapore, Taiwan, and Trinidad and Tobago. There were also extensive collections in the United States ; in California, Colorado, Florida, Hawaii, Louisiana, Maine, Maryland, Massachusetts, New Jersey, New York, Oregon, Pennsylvania, South Carolina, Texas, Vermont, Virginia, and Washington. I usually did these trips when I was traveling for other reasons, to attend meetings or consultations, in order to minimize travel costs.

This research required the establishment of a whole new range of activities in the laboratory. We added a natural products chemist, and a botanist, and developed a series of tests to determine if the medication had any effect on the replication mechanism of HBV. There were no established laboratory animals that could be infected with HBV nor was there then an adequate tissue culture system. However, woodchucks or groundhogs, (Marmota monax) are infected with woodchuck hepatitis virus (WHV) that is very similar to HBV. Hence, we developed skills for trapping and testing woodchucks and raising them in a laboratory setting, a very complicated and difficult operation.

Professor S.P. Thyagarajan at the University of Madras, India had done a controlled clinical trail on the effectiveness of Phyllanthus amarus on the HBV levels in carriers. We helped in the testing of the serum samples from the study and the analysis of the data. This first trial showed an impressive clinical effect. However, subsequent trials in other Asian locations did not confirm the results. We continued in our efforts to isolate the active principles and several other laboratories and commercial companies worldwide have continued research on the preclinical science. Although the plant continues to be used widely in India and elsewhere it has not (at least so far) resulted in a tested and widely used proprietary medication. Research continues and there may be one day another medication to add to the treatment of HBV and other viruses.

[bram44]

I will try to get more information on this "keezharnelli" medicine.

http://www.rediff.com/news/1999/mar/18heptb.htm

I am on Tenofavir treatment now, after 3 months will get myself tested for change in viral load etc... Then I will start this (of course need to inform my doctor). May be I will stop viral treatment and start this.