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Chronic HBV

Is chronic Hepatitis B is curable??
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your link is over 1 year old
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http://www1.easl.eu/easl2011/program/Orals/339.htm
Only 3 patients competely cured?
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Does this mean 100% cure rate or 90% cure rate
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good evening. hope this is it. finally finished the trial....
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The above post is almost 7 years old..and last news on Rep 9AC is that it disclosed the interim results in US & China on Nov'2012 and the were sucessful in removing the virus from body..

Now what is the next thing for Replicor ?/ I think they are complete wiht Trail 11 with discloser... Any thoughts what is their next work to get this drug to market??/
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http://www.replicor.com/Wall_Street_Reporter_Biomed_Business_Journal.pdf
I think it is used to treat many different viruses. So the drug should be on the way to be released.
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why 8 out of 9 patients. I am wondering what happened to that  1 person, the virus came back?
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http://www.replicor.com/debut_anglais2.htm
Patients who had cleared HBsAg from their blood with REP 9AC’ monotherapy were subjected to combination treatment with REP 9AC’ and either Pegasys™ or Zadaxin™.  Profound increases in anti-HBV antibodies or immune function were observed in all patients with as few as 6-10 weeks of combination treatment.  All patients have achieved HBV antibody levels seen in healthy patients after vaccination with a total of 12 weeks of combination treatment and many patients have achieved antibody titers > 1000 mIU / ml. In 8 out of 9 patients who have achieved this therapeutic vaccine-like response, they continue to control their viral infection off treatment.  REPLICor expects that short term  Zadaxin™ or Pegasys™ treatment given in combination with the HBsAg release inhibitor REP 9AC’ will achieve an effective, therapeutic vaccination in patients with chronic HBV infection, resulting in the achievement of durable immunological control in most patients, regardless of viral genotype or state of their HBV infection.
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Does creating a change.org petition help?
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hbv
which channel ?
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Avatar universal
and i m from asia....and i will try and hope that in dec one of top media channel of our country publish as a awareness that whats going on ....
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yes veteran you r right...y we have to wait .....when cure is there......lets start ...i think every one wants this ..so lets raise the awareness to people about fact....that how these drugs maker's and as wel as our government play with human health.....but for this we have to plan and unity and faith....now a days i think it is easy to approach to media....we can use media for this purpose..but  for this we hv to plan that how can we do this ......
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Avatar universal
I always do btw finish what I start. And Judging by the message you are sending me from your patrons I think I am at a good starting point ;)

Anyway please let us know if we get to see dr.Gish here so we can continue discussion about the problem that supposedly does not exist directly :)
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Starting a thread of plea is a good idea. Like a petition. If you are willing to take charge of this "project", I'm sure many will write about their story in the thread, me for sure. Pls start the thread and let's get it going!
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Avatar universal
Yeah that is what they reply with to everyone. Well we can all fly to Canada and occupy their premise building :) Just imagine what can this do is if 10,000 people show up.

Or we can start a thread of plea here on this forum, and get as many signatures as we can. And keep emailing them. People can some the story of their lives. Then we e-mail CNN and others with links. We can email Michael Moore too. There is a lot of things possible these days.

3-4 years wait yes it is great, but I just don't understand why we need to wait that long when they cured all 12 Bangladesh patients. And they did not die either in the process.

What do you all think?
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Avatar universal
Don't get me wrong. I am all for pushing replicor to release rep9ac as soon as possible. In fact, I have already emailed replicor and they replied the drug will be released no sooner than in 3-4yrs. So what is the next step i should do? What do you propose? Maybe you can show us the way as I am not good at this. Tks.
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Avatar universal
I am not scared if I die from Replicor drug. It worked for other people.

If they start accepting volunteers like me I will even pay for the medicine. And I am sure I am not the only one. We need to spread the word about their medication.

That is why I want them to come here and discuss things with us. If they go to the people they will get funding if this is the issue not only that a Nobel Price is guaranteed for this achievement. And I am sure major governments once they and the public become aware of this medicine will fund it.

Last year after tsunami and Fukushima the whole world donated funds to Japan. And in out case the whole world would donate to rid people of HBV.
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Avatar universal
Yes this forum is amazing. We are lucky to have people  like Stef2011 and studyforhope on this board.

I had terrible chest pains, and black hairy/grey/ sometimes yellow tongue for the past 6 years ever since my hbv. I have seen anywhere from 50-75 doctors during this type. And nobody could figure out what it was. I had about 50 HIV tests - which almost made me go insane. The bottom line these doctors could not figure it out how to treat it.. Nobody even heard of oxydative stress that Stef2011 has mentioned.

So following Stefanos advice and adding the vitamins he suggested, my check pains have gone. I have more energy, as well as general feeling of feeling better. And my tongue is slowly is clearing up. The doctors are silent.. they have no answer for me.

How much money I have spend outside of health insurance?

$10-13,000  on doctors visits.
and about $10,000 in blood tests..

with health insurance probably it all cost the health system $100K

And I have seen University level doctors that were clueless what to do.. Except adding TDF to ETV..

As for combo therapy yes, that is a novelty.. Even Dr.Gish is not doing it. And yes he does not have FibroScan either.
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Avatar universal
No FibroScan, no surface antigen quant test, no combo therapies, no zadaxin.!

Absolutely This is a FACT!!  NOT RANTING!!

I did not know until I found this forum. I learn a lot more here than from my doctors!
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Avatar universal
I can understand where is veteran coming from, his frustrations and disappointments of the US medical care. Even though I have only been living in the US for 2 yrs, I can already feel the "back-wardness" and lack of knowledge from GPs to gastroenterologists, compared to back in my country in Asia. That is why everytime I do a set of blood work, I always email back to my dr in Asia to get his opinion. I feel safer.

Now that we know Replicor has a cure, that is indeed very good news for us. But to say that they are withholding this cure for the sake of more profits, I cannot comment as I have no knowledge and proof. But I feel its good we follow up with them to give them a little more pressure, but we should not demand that they must release the drug in a super fast time like 1 yr. I all want the drug to be safe for everyone. And I think that is what Replicor is doing now - they are working on the drug development to cure EVERYONE, every type of virus/mutant hbv that different people will have. They cannot be slipshod on this as what if someone dies due to the drug? They have to be very certain its a 100% ready to be launched in the market. This protects themselves, as well as us. So meanwhile, let's be patient and see how the progress is moving. By next year we should hear some new updates from them. But if the update is the same as this year , or even last, then we all need to do more to pressure them. This is just my humble opinion.
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Avatar universal
" It can be done, yes.  But it is unsafe"

It is not absurd and is very doable if they are serious about eradicating HBV. Especially since those drugs happen to be used for other diseases. Zadaxin for example is none toxic. Can be added to any antiviral.  

As for banging on drug companies doors, well there is no need for that. The current laws that they have lobbied protect them.. We  can use the power of internet and wake people up by making them aware of what is actually taking place.

And the more of us stand up, the louder the voice would be.  You can relax btw and watch it form the side lines if it is getting you to nervous.

But some of us want some real answers as to why the drug that suppresses HBV surface antigen in 7-12 days is not being widely studied.
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Avatar universal
I have yet to read one forum post where you don't go on a tangent about the government or drug companies.  It is getting really old.  You need to spend more time outside, maybe go knock on the drug companies door in person and tell them all of your ranting.  I'm sure they will approve these drugs ASAP if they have to listen to your endless drivel.
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Avatar universal
1 year clinical trials stage 1-3 is absurd, regardless of whether it is HBV, HCV, HIV, HPV, EBV, HHV, etc.  That is like asking the airlines to fly 747s from China to US in 10 hours.  It can be done, yes.  But it is unsafe.
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Avatar universal
" I gave 10 ml of blood and got my HBsAg no problem"

Show the contract where it states in writing that there is only 10ML of we have to give. To get the test on the continuous bases. If they have changed their policy please confirm that. I offered 12 SSD tubes every time plus I pay money, simply because 700ml is a lot to give every time. They said no..  

btw..  I am not ranting  on this board, I am  exposing facts as they are, and rotten experiences I have had. Similar things you can read in the news papers quite ofter these days, about the level of corruption going on in the medical field these days. And that is why we have no cures for many diseases.

As for petitioning companies I constantly say over and over here lets all keep writing to Replicor and others. And have them come to this forum.. many of us have e-mailed them too. Do you see anybody from these companies come here  to this forum and  try to work out somethings with the people?  There is a lot of us. And people are trying desperate things, just read these threads more carefully.

how is that can be called ranting? We are frustrated.  No FibroScan, no surface antigen quant test, no combo therapies, no zadaxin. You call this normal for America?

GS9620 (Imiquimod) is not an unknown drug dude! :) It is used for cancer in higher doses, and as a cream called Aldara.. Also used to treat HPV, they know the sides.. No company especially as big as Gilead would go into clinical trials if there were major safety concerns.

Stef2011 here takes it in a much higher doses and without making a big deal. I guess he is the real researcher on here. The guy stopped his cirrhosis. How many doctors say they did that?

HBV better treatments regiments are here I listed them, the problem is finding doctors that are willing or even care to make the difference and at least work with those that are willing to be pioneers in taking these treatments. So we can all share here, on these forums and spread the knowledge.  

With regard to clinical trials for better meds for such a deadly virus as HBV yes the process CANNOT take 5 years.. Stages 1-3 maximum can be stretched out over the course of 1 year.. that is max.

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