How was my HBsAG NEGATIVE then INDETERMINATE and now REACTIVE

[viviva]

Hi, Im a 24 year old female. Got hep b from my mother at birth so it is chronic hbv. My reports as follow:

JAN 2018 - HBSAG: NEGATIVE (very shockingly as i was chronic but inactive)
MAY 2018 - HBSAG: INDETERMINATE (value of 16) (tested twice both times indeterminate result)

JAN 2019 - HBSAG: REACTIVE (Value of 38)
                 - HBV VIRAL LOAD (QUANTITATIVE) BELOW 20 IU/ML
                 - Log value Below 1.3
                 - viral load below 116 copies/ml
Basically viral load is present but below the detection and reporting range.
                 - LFTs are all normal range.

My burning questions are:
why did my hbsag go negative and give me hope? and why has it become reactive now?
Also, my viral load used to be UNDETECTED now why is it less then 20iu/ml?

Is my case becoming worse compared to last year? If i take care will it go back to undetected? I dont take any meds as im obviously an inactive carrier.

SOMEONE PLEASE EXPLAIN TO ME ALL THESE TRENDS AND WHAT IS HAPPENING.
Thank you

[hepbcurepls]

wow amazing , hbsag quant of 38 is great. we are hoping you clear. hopefully you can develop antibodies. since her hbsag is so low maybe one of these trials to knock hbsag down could be beneficial to her. i wonder if they tested on low hbsag patients before. regardless hopefully you clear and good luck.

[imran4535]

Hi,

These are great results! You could be very close to being functionally cured. There is an ongoing struggle between the virus and your immune system. Virus wants to spread and immune system wants to clear. Some people in your cause with very low HBSAG could try Pegylated Interferon to give you an immune boost to clear the virus. You may be one of the very lucky ones who can clear it.

Pegylated Interferon has a lot of side effects but in your case this may be your chance to get out of Hepatitis B for life. You should seriously look into this.

Scroll through these articles, there is a lot of studies on this, find the best Hepatologist in your country or even outside to discuss this possibility.
https://www.ncbi.nlm.nih.gov/pubmed/?term=interferon+hbsag