Aa
Aa
A
A
A
Close
Avatar universal

SGOT and SGPT increase and HBSAG Quantitative Decrease

12-07-2018 --> I had stopped tenofovir after 8 years taken it.
                         SGPT/SGOT --> 24/22
                         HBSAG Quantitative --> around 3000 for 1 yaer
                         HBV DNA --> Undetect

13-06-2019 --> SGPT/SGOT --> 36/62
                         HBSAG Quantitative --> 25000 (CMIA)

09-09-2019   --> SGPT/SGOT --> 40/56  
                              HBV DNA --> 1.7 X 10^8
      
17-06-2020 --> SGPT/SGOT --> 65/103  
                          HBSAG Quantitative --> 8071.89 (CMIA)

I want to restart tenofovir but my question is why my HBSAG Quantitative is decrease while my SGPT/SGOT always increase?
What is mean? Is it okay to restart my tenofovir/viread?
3 Responses
Sort by: Helpful Oldest Newest
9624973 tn?1413016130
Are you sure this is not a typo,  ( 3000  instead of 30,000 ) ?
12-07-2018 --> I had stopped tenofovir after 8 years taken it.
                         SGPT/SGOT --> 24/22
                         HBSAG Quantitative --> around 3000 for 1 yaer
Helpful - 0
Avatar universal
Sure, When I started tdf, my HBSAG Qty was 35000 and  When I stoped tdf, my HBSAG Qty was 3000 (12-07-2018)
Helpful - 0
3 Comments
hbsag relapsed and it is obvious hbsag was too high when you stopped tdf, only hbsag less than 100iu/ml have chances to clear
I am curious what made you stop tenofovir after 8 years, since the drop rate would be around 4000UI HbsAg/ year..... Now, of course, in case the drop was more linear and still going down, it would've been under 1000 in one more year.
My doctor has asked to stop. I did not know  his reason and I though everything is OK include my kidney (ureum & creatinine was still normal range).  But now he ask me to take tdf again .
Avatar universal
So, Is okay to take tdf again or wait a couple of months to see HBSAG qty?
Helpful - 0
2 Comments
you relapsed so your tcells are not working against hbv, i d restart tdf as soon as possible
Thank you Stef. I will restart.
Have an Answer?

You are reading content posted in the Hepatitis B Community

Didn't find the answer you were looking for?
Ask a question
Popular Resources
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
Can I get HIV from surfaces, like toilet seats?