Hi,please @stef2011 and others help me check into this.i was diagnosed for hbv in 2012 but didn't start any treatment because lft was normal,no idea about viral loads then, but used to have heartburn so i did endoscopy but nothing was found, was advised by gastro to eat healthy. So fast forward to last year Oct,I started having body pain with burping,and a particular lower left abdominal pain,and tingling on left leg with pain and back pain. I did several urinalysis,urine msc and ultrasound,protein was found in urine,sti and one out of all the ultrasound said renal parachema or so,family Dr said protein could be from not drinking enough water and did physical examination then said left abdominal pain from big colon,placed me on drugs for 2 weeks,asked me to stop eating some food,and dismissed the renal parachema. After 2 weeks my poo,started forming well and not watery as it used to be.but left lower pain persisted,he order ct abdominal pelvic scan,result came out nothing was found and no inflammation.pain persisted with serious body pain.later went to see a gastro,did colonoscopy,everything was normal,he said ibs change diet,I did but no changes still,went to see nephrologist, in December showed him all my past test results,ordered urinalysis,msc urine,creatinine and ct urogram with contrast.all came back fine with creatinine of 69.8 umol/L (62.0 to 106.0 range).from the scan he noticed my spine wasn't too curved so he said not normal and prescribed a muscle relaxant drugs,prior to that I had done hbv dna 7134 iu/ml with normal lft
Total bilirubin 0.5 mg/dl range 0.1 to 1.2
Direct bilirubin 0.1 mg/dl 0 to 1.0
Total protein 6.2 mg/dl 6.0 to 8.7
Albumin 3.6 mg/dl 3.5 to 5.0
Alt 13 iu/l 0.1 to 39
Ast 06 iu/l 0.1 to 40
Alkaline phosphate 101 iu/l 98 to 279
Did fbc all normal with platelet of 235,lipid profile normal too.
I asked if I can start taking drugs for hbv he said no. So went back to the gastro,he checked the ct urogram film and referred me to bone hospital, saw a spine Dr, he ordered Mri and did mri all spine ,was diagnosed with degenerative disc diseases,he said minor go do physiotherapy, I started that but with no drugs. Pain persisted,I was weighing 67kg,age 35,male. In February my weight dropped to 57kg. I met another gastro,presented my case,saw all the results and placed me on tenofovir immediately, and ordered tests Afp,thy,cea,calprotectin and pylori, all came back well
Afp 2.2 ku/l 0.0 to 5.8
Cea 1.4 ug/l 0.0 to 3.5
She also prescribed probiotics,dustpatalin and anti depressant drug. She concluded that no inflammation ,but ibs,see in 3 months.
After 2 months, the left abdominal pain stopped and felt much better but I noticed yellow urine sometimes, I was told livolin could be the cause too,but I drink lot of water. Into the 3rd month, I started having itching on my ankles , wrist, sometimes at night,it goes and comes,i asked around if this could be side effects of tdf but nobody knows really.plus i am not gaining weight still 57kg .Last week made it 3 months I started tdf and due for appointment,I did lft,urinalysis,ultrasound scan,hbv panel and dna/ surface antigen quantification.
Total bilirubin 7 umol/L range 3 to 26
Direct bilirubin 3 umol/L 2 to 7
Total protein 72 g/l 60 to 80
Albumin 49 g/l 35 to 50
Alt 42 iu/l >40 H
Ast 30 iu/l 15 to 40
Sgt 53 iu/l 0 to 64
Kidney function test
Sodium 137 mol/l 135 to 150
Potassium 3.4 mol/l 3.5 to 5.1 L
Chloride 103 mol/l 98 to 107
Bicarbonate 25 mol/l 21 to 29
Creatinine 79 mol/l 80 to 115 L
Egfr ckd kpi >89 mil/min
Hepatitis b cab positive
Core value 7.98 s/Co
Hep b surface ag quantity 24280 iu/ml
Hepatitis b sab Non immune
Hepatitis b surface ab value 0.58 miu/ml
Hepatitis b virus dna Undetected iu/ml
I started panicking when I got this results because everything was in range before I started tdf,Alt was raised and my Potassium level dropped,last week at the appointment i did vitals and noticed I dropped to 55kg again,itching continued. The gastro said I worry too much and probably not eating well that this could affect my weight as well.i asked about the itching she said not sure but would check the leaflet for tdf.she said with all the test results I am doing okay but I refused to believe that,why platelet dropped from 231 to 221,why Alt raised to 42 from being normal before tdf likewise Potassium?why weight loss like that?She said we should continue to monitor.
During these periods my left lower abdominal pain returned I started to panic really bad,she said since I don't believe I am okay that we should do fibroscan,scheduled for yesterday but was tensed since last week to yesterday not knowing what the findings could be,weighed myself at home about 4 days ago and still 55kg,getting to hospital yesterday did vitals and they said 53.5 kg,I almost broke down in tears what's going on really. I ended up doing the fibroscan,last food was dinner around 7pm the other night and did the test 11am yesterday morning.result below
Median stiffness 4.6 kpa
Iqr 1.4 kpa
Iqr/med 30 percent
Valid measures 20
Success rate 83 percent
I asked about the cap number she said she's sure I don't have fatty liver but I also think the machine didn't have that feature.
I felt the fibration several times and she placed it diffrent areas during the test.she performed it in her office and she's a gastro and hepatologist.
She concluded that I should continue the tdf and livolin,check back in 3months with just lft and afp test.she said eat well and continue with dustpatalin and enterogermina for the abdominal pain.
My questions,I had tried all.possible best to get the answer to weight loss,left lower abdominal pain and body cracking sound most times but no certain answer.what can I do regarding that ?could the itching be from tdf and weight loss ? Is the fibroscan a good result?I stopped eating many foods since last year and I don't drink nor smoke.what could be the cause for atl elevation and low Potassium? Can worrying too much affect weight and probably activate ibs?and lastly,with the left lower abdominal pain,I noticed I go to toilet every morning and once a day which stopped when I took the prescribed drugs but started again last week.. is it really ibs.
I am so sorry for the long story but I just want anyone trying to respond to understand my journey.i am new here please help my case thank you.