Aa
long term after effects post interferon
My last interferon injection was 12 months ago. I feel tired, lethargic, my bones ache in the morning esp in my feet. I'm in bed asleep by 10-30....and now i've developed a fissula, a perenanal abcess. My doctor thinks it may be because since the interfeon my immune system is v.low to warding off infections.
Are these symptoms shared by others.
Are these symptoms shared by others.
Interferon is poison! I wish I never took it and waited for the newer treatment. My body has never been the same. Within 6 months of stopping treatment I had diabetes. I have 3 enlarged axillary lymph nodes that I had to have biopsied and are being carefully built watched. I have horrible anxiety and early onset menopause. It's been over 5 years and I feel like this treatment aged me and just changed me. I literally see my life as before and after interferon. I regret ever ever going anywhere near it!
1 Comments
Me, too.
However, I got the virus cleared. Who knows what this infection would have caused me.
Waiting at that time was not an option for me. I wanted to get the best treatment available.
Here I am.
However, I can assure you that now with all the supplements and vitamins, I am much better than 5 years ago. Improvement is slow, but it is there.
Don't give up. Our bodies can heal if we help them by providing what they need.
However, I got the virus cleared. Who knows what this infection would have caused me.
Waiting at that time was not an option for me. I wanted to get the best treatment available.
Here I am.
However, I can assure you that now with all the supplements and vitamins, I am much better than 5 years ago. Improvement is slow, but it is there.
Don't give up. Our bodies can heal if we help them by providing what they need.
Interferon is the worst thing that happened to my life. I was treated in 2014 and after all this time i have never felt the person i was before. I used to enjoy life, have friends, go out. I am 20 years old right now and I am supposed to be on the best point of my life, but I just do not feel so. I wished I never had done that treatment. I have ADHD, and right now it seems that I suffer from depression and anxiety also. I am just tired of all this.
I was treated for HCV and cleared in 2004. I have many immune issues since using the interferon and ribavirin. Thought I would share some things that helped and ask for help. I have been on thyroid replacement 2004, I take natural thyroid plus T3. Not everyone can convert T4 into T3. I am sensitive to many foods and chemicals and perfumes. I try to eat organic when possible. Nightshades(potatoes, tomatoes, peppers, eggplant,tobacco) caused me muscle and joint pain. Corn caused me fatigue and severe brain fog. I also need to avoid gluten, dairy, soy, nuts, sugar and a few other foods. I have airborn allergies, of course I have cats and dogs. Quercetin helps for this. One of the few exercises I can tolerate is rebounding. This is jumping or jogging on a small expensive trampoline. I also take a lot of supplements.
Has anyone else developed photosensitivity? Sun exposure causes me extreme fatigue the next day. I also feel like the skin is burnt and can get discoid rashes from short exposure.
I also have muscle weakness and the muscles fatigue very easily.
I also had to figure most of these things out for myself.
Has anyone else developed photosensitivity? Sun exposure causes me extreme fatigue the next day. I also feel like the skin is burnt and can get discoid rashes from short exposure.
I also have muscle weakness and the muscles fatigue very easily.
I also had to figure most of these things out for myself.
I did treatment in 2002. I did clear the virus, but have never recovered from treatment. Chronic fatigue, pain, personality change, no drive, don't care about doing much of anything.
I have been to all kinds of doctors. Tried lots of different supplements and drug therapies. Nothing has been able to stabilize me to live a quasi-normal life.
Sometimes I can do things and get out and about, then I get hit by a wave of fatigue and crash into bed for a few days to a week.
I do find that acupuncture will help me crawl back out of the hole rather than just waiting for my body to recover. Massage helps for the body pain.
Frankly I have given up on seeing doctors. I don't think they know what is truly wrong so there's no way that they can treat it.
Fortunately, this horrible treatment is no longer being used so there won't be anymore people created with this syndrome and no help.
I have been to all kinds of doctors. Tried lots of different supplements and drug therapies. Nothing has been able to stabilize me to live a quasi-normal life.
Sometimes I can do things and get out and about, then I get hit by a wave of fatigue and crash into bed for a few days to a week.
I do find that acupuncture will help me crawl back out of the hole rather than just waiting for my body to recover. Massage helps for the body pain.
Frankly I have given up on seeing doctors. I don't think they know what is truly wrong so there's no way that they can treat it.
Fortunately, this horrible treatment is no longer being used so there won't be anymore people created with this syndrome and no help.
1 Comments
kratom has helped me
2000 Interferon w/Ribavirin and in 2010 pegyast w/Ribavirin....I'll make this short....pretreatment i was 37 years old bench pressed over 300 pounds. Was kind of a health nut. Worked as a mechanic 10-12 hours a day..felt great.Opened my own shop and was doing great.2006 it hit me and stopped me dead in my tracks one morning,went to dr. pain meds back to work.Long story short had to quit working any and since have been DX with...SLE Lupus,RA,Sjogrens,Fibro.,Throid problems,many back and cervical problems and the number one......Chronic Pancreatitis which is at least 10 times worse then treatment and hep. C combined...I wished i would have smart enough back then to do my own research on treatment.....God help us all.....and i just hope any who have treated the best of luck.....
Hep C treatment in 2008 made me permanently sick, drastically and permanently impaired my liver function, caused me to spend my life savings while utterly fatigued and unable to get out of bed for three years, addled my brain, and almost certainly shortened my life.
At least it cured me of western medicine.
At least it cured me of western medicine.
@maie13
If you can financially afford it find a good naturopath. I was offered therapy by someone before I started Interferon. At that time I was indoctrinated quite well and wanted to get the best modern treatment. I never imagine that it would change my life forever. I don't now much about the newer treatments. Maybe they are better, maybe they are not. Wait for ten years and see what people tell then...
Support your immune system. Vitamin A is essential in viral immune response as well as in cell differentiation. In order for Retinol to have therapeutical effects you probably will need high doses. You will need a doctor who can help you with dosing and monitor your liver function as in high doses Vitamin A can also be liver toxic and you liver is already affected by the virus.
Homeopathy and naturopathy are not the same things. Nature is powerful and our bodies are most powerful in healing themselves. I personally don't believe in homeopathy.
When I started treatment there was the "miracle" of those people that had antibodies but no viruses anymore. At that time it was said that the antibodies remain in the body troughout life. Well, now they found out that it is not true. Even the antibodies response of our bodies can be deleted.
http://www.nature.com/nm/journal/v6/n5/full/nm0500_578.html
However, it probably depends on how much your liver is already affected. I wouldn't know what to recommend, but probably I myself would for one or two or three years try alternative therapies first.
If you can financially afford it find a good naturopath. I was offered therapy by someone before I started Interferon. At that time I was indoctrinated quite well and wanted to get the best modern treatment. I never imagine that it would change my life forever. I don't now much about the newer treatments. Maybe they are better, maybe they are not. Wait for ten years and see what people tell then...
Support your immune system. Vitamin A is essential in viral immune response as well as in cell differentiation. In order for Retinol to have therapeutical effects you probably will need high doses. You will need a doctor who can help you with dosing and monitor your liver function as in high doses Vitamin A can also be liver toxic and you liver is already affected by the virus.
Homeopathy and naturopathy are not the same things. Nature is powerful and our bodies are most powerful in healing themselves. I personally don't believe in homeopathy.
When I started treatment there was the "miracle" of those people that had antibodies but no viruses anymore. At that time it was said that the antibodies remain in the body troughout life. Well, now they found out that it is not true. Even the antibodies response of our bodies can be deleted.
http://www.nature.com/nm/journal/v6/n5/full/nm0500_578.html
However, it probably depends on how much your liver is already affected. I wouldn't know what to recommend, but probably I myself would for one or two or three years try alternative therapies first.
2 Comments
Frieda1979 - while I certainly agree with you about homeopathy (I think most people don't even know what it is - wikipedia has a fantastic article on it including this from the experts "Modern advocates of homeopathy have proposed a concept of "water memory", according to which water "remembers" the substances mixed in it, and transmits the effect of those substances when consumed."!
I don't believe that a naturopathy doc can help me at this point. Before treatment having destroyed my life acupuncture was effective but after many months of to see if it would help my ancient Chinese doc said that Western medicine was too strong for his needles!
I have a new GP who is more of an Integrated doc who I was very impressed with. I will be looking to him for new test to run as for the most part all my test come back within normal ranges (except for various iron levels which fluctuates between severely LOW to crazy HIGH!)
I don't believe that a naturopathy doc can help me at this point. Before treatment having destroyed my life acupuncture was effective but after many months of to see if it would help my ancient Chinese doc said that Western medicine was too strong for his needles!
I have a new GP who is more of an Integrated doc who I was very impressed with. I will be looking to him for new test to run as for the most part all my test come back within normal ranges (except for various iron levels which fluctuates between severely LOW to crazy HIGH!)
Fluctuating iron might be a consequence of inflammatory processes in your body.
Vitamin A is important for keeping off infection and also for storing iron in the body.
Another nutrient that is related to this is Zinc. It acts antiinflammatory and it is needed for building the proteins that store Vitamin A in the body.
Both, Zinc and Vitamin A are depleted during interferon treatment.
Look at
https://www.ars.usda.gov/ARSUserFiles/80400530/pdf/0910/Table_1_NIN_GEN_09.pdf
You will see that probably the biggest part of the population in the US is eats roughly half of Vitamin A in their diet than the RDA recommend, which is 900µg.
Check the articles I have posted in my comment below. Chances are low, that one will compensate such a bis "disturbance" of a biological system by "normal" eating alone.
Hep C treatment is chemotherapy. But people are left alone with their side effects and symptoms. There would be many ways to help peoples bodies do recover from a) the infection by the virus and b) the treatment itself.
And... Supplementing vitamins and minerals is not homeopathy but hard biochemical facts :)
Did the test show any results?
And on a side note, after five years of struggling with synthroid dosage and all the supplements I take, I finally start to feel good again. I think each of us bring sa different vulnerability with him. I can tell what helped me, but I don't know what exactly the condition of the other person is. There are however studies and publications as the ones I posted below that can at least hint into several directions.
Our bodies have an amazing plasticity. They have the ablity to recover to at least some extend, if we give them what they need.
Vitamin A is important for keeping off infection and also for storing iron in the body.
Another nutrient that is related to this is Zinc. It acts antiinflammatory and it is needed for building the proteins that store Vitamin A in the body.
Both, Zinc and Vitamin A are depleted during interferon treatment.
Look at
https://www.ars.usda.gov/ARSUserFiles/80400530/pdf/0910/Table_1_NIN_GEN_09.pdf
You will see that probably the biggest part of the population in the US is eats roughly half of Vitamin A in their diet than the RDA recommend, which is 900µg.
Check the articles I have posted in my comment below. Chances are low, that one will compensate such a bis "disturbance" of a biological system by "normal" eating alone.
Hep C treatment is chemotherapy. But people are left alone with their side effects and symptoms. There would be many ways to help peoples bodies do recover from a) the infection by the virus and b) the treatment itself.
And... Supplementing vitamins and minerals is not homeopathy but hard biochemical facts :)
Did the test show any results?
And on a side note, after five years of struggling with synthroid dosage and all the supplements I take, I finally start to feel good again. I think each of us bring sa different vulnerability with him. I can tell what helped me, but I don't know what exactly the condition of the other person is. There are however studies and publications as the ones I posted below that can at least hint into several directions.
Our bodies have an amazing plasticity. They have the ablity to recover to at least some extend, if we give them what they need.
You seriously believe that you ending it will bring your parents peace??? This Post Interferon thing is cyclical or so I have found. If you overdo it you end up crashing and then the depression sets in but if you ride it out it passes.I have simplified my life as much as possible but any stress/overdoing it will kick me off into the cycle again. Please try to ride it out and if you don't have to see your parents every day,see them on the positive days and put a happy face on for them if at all possible.Don't forget,you are not alone in the "bubble" and we all understand how you are feeling at the moment. I have found calling the Hepatitis C Trust for a post treatment chat really helpful at times of deepest distress,they have all been through treatment and are good people.
I was treated in 2014 with PEG, Riba and Sovaldi for 12 weeks and have never been the same. I lost my skills on the guitar and my love for music and musicmaking. then i lost my friends because they all were musicians.
I was really good looking and loved to go out and socialize. after treatment i began to age at an unbelievable fast rate and stopped to go out because i shamed for myself in social situations because i stumble over words all the time, don't feel anything for other people and my skin is covered with a rash since treatment, forget everything etc...) so.. I changed from a good looking, happy and skillful 25 year old musician and programmer into an ugly, desperate, lonely, dumb and untalented 27 year old. thank you Roche.
I was really good looking and loved to go out and socialize. after treatment i began to age at an unbelievable fast rate and stopped to go out because i shamed for myself in social situations because i stumble over words all the time, don't feel anything for other people and my skin is covered with a rash since treatment, forget everything etc...) so.. I changed from a good looking, happy and skillful 25 year old musician and programmer into an ugly, desperate, lonely, dumb and untalented 27 year old. thank you Roche.
I was on pegintron and Ribavirin in 2003. I never fully recovered from the treatment. I guess that both drugs stress the whole endocrine system. It is not only the virus which is attacked but the drugs induce changes in the whole body/endocrine system. For me the key point of getting better was to get a treatment for the thyroid. From various symptoms I know now that I was hypothyroid since interferon, but at that there wasn't a single thyroid test.
I don't know who else expereinced this, but e.g. in the time of the treatment I was wetting my bed almost every night, I had herpes outbreaks almost every day and it was terrible. I also lost my hair and 10kg within the first month. All these side effects show how deeply the treatment effects/interacts with the endocrine system.
One possible explanation is that by creating a state of high immune system response to the virus our bodys are running 125 miles per hour for half a year while we don't add more fuel - in the sense of more nutrients.
E.g. when you smoke the nicotine "forces" the adrenal glands to produce more cortisol than your body would produce under normal circumstances. Nicotine also forces your brain to produce more dopamine than it would do normally without the external trigger nicotine. Now it is only chemical reactions in your brain and adrenal glands that create dopamine/cortisol. For these chemical reactions you need e.g. Vitamin C. If you now constantly overuse these pathways by smoking but at the same time don't add Vit C to your daily intake of whatever it will lead to a Vitamin C depletion in the body.
Similar is probably true for interferon treatment. The interferon triggers a strong immune system response and since it is itself a strong external stimulation it will make many resources go that path towards fighting against the virus. Ribavirin has "hypomagnesemia" listed as adverse effect.
But these nutrients will then be missing at other places. It will take some time to restore the balance. It takes time to detox after the treatment. It will also take time until the body has restored it's balance. This is a strongly simplified view on the action of interferon, but it is one part of the whole process and it is the part that we can influence.
But if you don't know all this - and I certainly didn't in 2003 - you might think it is just a matter of time and compensate the tiredness by e.g. drinking more coffee and smoking. But this can increase the imbalance. If there is a thyroid condition as well the body will absorb even less nutrients since the metabolism is slowed down.
If you eat high carb and sugar then your metabolism will need even more magnesium, since it is needed for glycolisation and so on...
I don't know if this will help anyone reading this but by taking thyroid medication and refilling depleted iron, Vitamin C, Vitamin D, Magnesium, and B Vitamins and so on my condition improved a lot in the last two years. I was suffering since the treatment for almost 13 years and I was close to loosing everything since I simply couldn't function anymore. Now I don't have brain fog anymore, by back doesn't hurt in the morning when I get up, I feel joy and energy again, my depression had gone. I didn't get much help from doctors. They told me I am simply stressed and wanted to give me antidepressants. So I was doing research on my own.
Don't think that small amounts of Vitamins will help to restore the balance.
Feel free to ask questions. I don't know if this is the right path, but I know that I feel so much better. I started to recognize myself again. Our bodies are designed to life and I believe that if we give them all they need they will be able to restore the balance.
Get your thyroid tested and if you can afford it get the nutrients tested. If you can't then you have to do trial and error. Which is what I did for most.
I don't know who else expereinced this, but e.g. in the time of the treatment I was wetting my bed almost every night, I had herpes outbreaks almost every day and it was terrible. I also lost my hair and 10kg within the first month. All these side effects show how deeply the treatment effects/interacts with the endocrine system.
One possible explanation is that by creating a state of high immune system response to the virus our bodys are running 125 miles per hour for half a year while we don't add more fuel - in the sense of more nutrients.
E.g. when you smoke the nicotine "forces" the adrenal glands to produce more cortisol than your body would produce under normal circumstances. Nicotine also forces your brain to produce more dopamine than it would do normally without the external trigger nicotine. Now it is only chemical reactions in your brain and adrenal glands that create dopamine/cortisol. For these chemical reactions you need e.g. Vitamin C. If you now constantly overuse these pathways by smoking but at the same time don't add Vit C to your daily intake of whatever it will lead to a Vitamin C depletion in the body.
Similar is probably true for interferon treatment. The interferon triggers a strong immune system response and since it is itself a strong external stimulation it will make many resources go that path towards fighting against the virus. Ribavirin has "hypomagnesemia" listed as adverse effect.
But these nutrients will then be missing at other places. It will take some time to restore the balance. It takes time to detox after the treatment. It will also take time until the body has restored it's balance. This is a strongly simplified view on the action of interferon, but it is one part of the whole process and it is the part that we can influence.
But if you don't know all this - and I certainly didn't in 2003 - you might think it is just a matter of time and compensate the tiredness by e.g. drinking more coffee and smoking. But this can increase the imbalance. If there is a thyroid condition as well the body will absorb even less nutrients since the metabolism is slowed down.
If you eat high carb and sugar then your metabolism will need even more magnesium, since it is needed for glycolisation and so on...
I don't know if this will help anyone reading this but by taking thyroid medication and refilling depleted iron, Vitamin C, Vitamin D, Magnesium, and B Vitamins and so on my condition improved a lot in the last two years. I was suffering since the treatment for almost 13 years and I was close to loosing everything since I simply couldn't function anymore. Now I don't have brain fog anymore, by back doesn't hurt in the morning when I get up, I feel joy and energy again, my depression had gone. I didn't get much help from doctors. They told me I am simply stressed and wanted to give me antidepressants. So I was doing research on my own.
Don't think that small amounts of Vitamins will help to restore the balance.
Feel free to ask questions. I don't know if this is the right path, but I know that I feel so much better. I started to recognize myself again. Our bodies are designed to life and I believe that if we give them all they need they will be able to restore the balance.
Get your thyroid tested and if you can afford it get the nutrients tested. If you can't then you have to do trial and error. Which is what I did for most.
One more thing i keep reading people say that side effects will go away after treatment.....Guess who says this?...People who never treated....So if your one of these please don't offer advice if you have no clue about treatment.....anyone can can e-mail me at ***@**** to talk about treatment...or post treatment
2 Comments
i agree 100%
I would be glad to share some own experience. ***@****
I just found this article
http://www.ncbi.nlm.nih.gov/pubmed/19042060
another nutrient that is depleted during Hep C and interferone treatment is zinc.
As well as Vitamin A
http://www.ncbi.nlm.nih.gov/pubmed/7196691
Good luck to everyone! Don't give up, even after 13 years our bodies have the ability to recover if we provide them with the nutrients they need.
http://www.ncbi.nlm.nih.gov/pubmed/19042060
another nutrient that is depleted during Hep C and interferone treatment is zinc.
As well as Vitamin A
http://www.ncbi.nlm.nih.gov/pubmed/7196691
Good luck to everyone! Don't give up, even after 13 years our bodies have the ability to recover if we provide them with the nutrients they need.
1 Comments
I've been on interferon for just coming up to 12 months. Since November I had been experiencing quite a lot of symptoms so end of this year I thought it would be best for me to stop taking the injection treatment and go back to the previous treatment I was on hydroxicarbomide. I was developing hair loss, pale skin, derealisation, muscle pain and weakness, numbness conjunctivitis, A cough which continued for a while - dry skin. It's currently week 3 of being off interferon and my haematologist had just put me back on the hydroxi - My platelets had crept up to 795 from 535 which was only 3 weeks ago so a massive jump when I wasn't on any treatment. The Interferon treatment I found wasn't really controlling my platelets as well as Hydroxi which in my opinion is a better treatment. At the moment weening off one drug and taking another I have developed pins and needles all over my body which is constant currently, increased sensitivity to hold and cold, burning sensation, crawling/itching, prickling. When I first started the treatment I seemed fine but after 9 months it just seemed to get worse. The reason for me coming off the old treatment was that I wanted to get pregnant but now my plans have changed. I'm just hoping that I can solider on and that the symptoms will go. But reading on here that may not be the case - unless it's a long process - Have found I've had to be patient but sometimes It can get quite frustrating. Would love to hear from anyone that's been though the same type of symptoms.
Not just the US. Processed empty foods, sugar, work, sickness. Somewhere in between death and life. Not sick enough to cost too much money, not healthy enough to have excess energy too be able change the system. Everyone entrapped in their own existential fights. Wonderful trap it is. It is a worldwide problem and people sleep.
If you are having an infection in the moment of the blood test the ferritin value (Iron storage) will be much higher. That is why the result can be false positive. CRP should always be measured at the same time to exclude false high ferritin results. That might explain why the ferritin "jumped" that much. Your doctor should know this. I increased my iron ferritin value from 13 ng/ml to above 42 ng/ml with oral supplements only. I had to stop since it is causing me stomach pain so I just take it once in a while. 13 is the lower bound of the reference range of your 6 = nothing, as I guess from the numbers you give. And yes, 6 is nothing, 26 is still very low. As far as I know above 30 is still not much, but also not bad.
You can do the B12 subcutaneously yourself. At least in Europe this is a somewhat common practice. I never tried it myself, since I am not sure if it will help me.
The discoid rash and sun sensitivity can be a symptom of niacin deficiency. If you want to try it, then use Nicotinic Acid and NOT Nicotinamide, since Nicotinamide is known to stress liver function. Did you get your exocrine (!) pancreatic function tested? Did you get tested for rheumatic diseases? They can also cause similar symptoms and are autoimmune problems that can be triggered by IF.
I have developed photosensitivity as well. I am trying zinc now and niacin. I just got diagnosed with pancreatic insufficiency. I probably had that for years already.
Until now, things that helped me were protein rich diet (1g/kg and day), lots of Vitamin C (1-2g), magnesium (400mg-800mg), iron (100mg), Vitamin A (25.000 i.E.) and of course the thyroid hormones. Of course it all canot be well processed if there is exocrine pancreatic dysfunction. Now I try the zinc to support my pancreas and I will see what happens.
I also had to figure out most of the things myself. I am glad that I invested so much time in the research since I am so much better than 3 years ago.
Interferone and Ribavirin trigger a strong immunological response against the virus. I imagine that that way we use much more of our resources in terms of minerals, vitamins proteins. E.g. I lost 10 kg in three months, had constant fever, lost hair and many other side effects. That costed the body energy and nutrients. BUT, if there is some imbalance it might cause other imbalances, as e.g. zinc deficiency and/or niacin deficiency and others can cause diarrhoea and pancreatic dysfunction, thus impairing nutrient uptake in the gastrointestinal tract. Depending on lifestyle and knowledge it can become a downward spiral.
Trust your body and your symptoms they will tell you what you need. Generally avoid sugar and processed food. Since it doesn't contain any nutrients at all anymore. It will worsen every imbalance that is there.
I believe that with time and the right building blocks (nutrients) the body can heal a lot of stuff away. It doesn't happen instantly, but it can.
Treatment in my case is already 13 years ago.
You can potentiate the effect of Curcumin with black pepper. Piperin acts on the same Cytochrome P450 enzymes that process Curcumin and by that preventing Curcumin of being processed by the enzyme too early.
I have developed photosensitivity as well. I am trying zinc now and niacin. I just got diagnosed with pancreatic insufficiency. I probably had that for years already.
Until now, things that helped me were protein rich diet (1g/kg and day), lots of Vitamin C (1-2g), magnesium (400mg-800mg), iron (100mg), Vitamin A (25.000 i.E.) and of course the thyroid hormones. Of course it all canot be well processed if there is exocrine pancreatic dysfunction. Now I try the zinc to support my pancreas and I will see what happens.
I also had to figure out most of the things myself. I am glad that I invested so much time in the research since I am so much better than 3 years ago.
Interferone and Ribavirin trigger a strong immunological response against the virus. I imagine that that way we use much more of our resources in terms of minerals, vitamins proteins. E.g. I lost 10 kg in three months, had constant fever, lost hair and many other side effects. That costed the body energy and nutrients. BUT, if there is some imbalance it might cause other imbalances, as e.g. zinc deficiency and/or niacin deficiency and others can cause diarrhoea and pancreatic dysfunction, thus impairing nutrient uptake in the gastrointestinal tract. Depending on lifestyle and knowledge it can become a downward spiral.
Trust your body and your symptoms they will tell you what you need. Generally avoid sugar and processed food. Since it doesn't contain any nutrients at all anymore. It will worsen every imbalance that is there.
I believe that with time and the right building blocks (nutrients) the body can heal a lot of stuff away. It doesn't happen instantly, but it can.
Treatment in my case is already 13 years ago.
You can potentiate the effect of Curcumin with black pepper. Piperin acts on the same Cytochrome P450 enzymes that process Curcumin and by that preventing Curcumin of being processed by the enzyme too early.
but maybe i will find a way out to this mess... i have a great way to undo all the damage that has been done... but i need $12.000 for that...
2 Comments
Hi Lookbehindyou ... Otter watcher is right... It is cyclical and I remember you posting at times when you were doing comparatively well. Am so sorry that you are having a horrible time... Hang in there and it will shift.
I seriously want to know how you are doing 8 years later. I hope you did hang in there and have had some small improvement.
Sincerely, Faithforhealing
Sincerely, Faithforhealing
i can't put on a happy attitude when i'm not happy. that will not work. I don't overdo things. i sit in my room on the floor and read through the internet. i don't even do anything! I can't cut short on my life. that too will not work. i don't want it and i would rather die than living this low life forever. no, thanks. without me.
My father and my mother who were so happy in the beginning because I treated the virus and they visited me with merry faces to ask if i need anything and how i was doing... after treatment i tried everything to get back to life and happy again and nothing helped. i can't continue to look in the sad and tired eyes of my father and my mother who are so sad to see their only son deteriorate... I have to end it, then they can find peace i guess.
So glad that you are not having side effects from the new drugs. Sending best wishes to you for success and an easy passage. I was lucky enough to clear with the old regime in 2014 but also have had long term side effects.
thank you for posting your story , all the best .. simon
thank you for posting your story , all the best .. simon
I had long-term effects after the first interferon/ribavirin treatment in 2003 and the second peginterferon/ribivirin treatment in 2012.
After the first treatment in 2003, I had little energy for a few years. After having been very socially active and physically fit between 1997 and 2003, I didn't go out much and gained about 40 pounds from lack of activity. I became depressed after a few months on treatment, and the depression continued for six months after the end of treatment. I had low libido after the first treatment, especially for the first several months.
Since the first treatment, several activities I previously had excelled at such as snooker, I'm no longer very good at. I became less competent in my work, and had to try extra hard to do well. My ability to give a presentation isn't the same as before, because I'm somewhat forgetful and stumble over my words from time to time.
There was a strange kind of rash I had before the first treatment, which came back and remained for a week or so about every six months for a few years after the first treatment, in exactly the same place.
During the second treatment in 2012 for 28 weeks, I had much more severe side effects than during the first, but the after effects were virtually the same: depression, forgetfulness/confusion by times, lessening of cognition/reduced skills. However, I lost 40 pounds during the second treatment, and since 2012 I've have been somewhat more physically active, keeping the weight-gain down to just 20 pounds since 2012.
I failed to achieve SVR after those two treatments, but right now I'm on a Merck clinical trial without interferon (grazoprevir, MK-3682, and MK-8408 plus ribavirin for 16 weeks). So far, there seems to be no side effects whatsoever from the first three drugs. The ribavirin side effects of dry skin, easily tiring from low RBC, and sleep disturbance seem not so severe and much easier to deal with without the far worse psychological side effects of interferon.
I'm very thankful for these new drugs, which I understand also have better success rates than interferon for people with cirrhosis like myself.
After the first treatment in 2003, I had little energy for a few years. After having been very socially active and physically fit between 1997 and 2003, I didn't go out much and gained about 40 pounds from lack of activity. I became depressed after a few months on treatment, and the depression continued for six months after the end of treatment. I had low libido after the first treatment, especially for the first several months.
Since the first treatment, several activities I previously had excelled at such as snooker, I'm no longer very good at. I became less competent in my work, and had to try extra hard to do well. My ability to give a presentation isn't the same as before, because I'm somewhat forgetful and stumble over my words from time to time.
There was a strange kind of rash I had before the first treatment, which came back and remained for a week or so about every six months for a few years after the first treatment, in exactly the same place.
During the second treatment in 2012 for 28 weeks, I had much more severe side effects than during the first, but the after effects were virtually the same: depression, forgetfulness/confusion by times, lessening of cognition/reduced skills. However, I lost 40 pounds during the second treatment, and since 2012 I've have been somewhat more physically active, keeping the weight-gain down to just 20 pounds since 2012.
I failed to achieve SVR after those two treatments, but right now I'm on a Merck clinical trial without interferon (grazoprevir, MK-3682, and MK-8408 plus ribavirin for 16 weeks). So far, there seems to be no side effects whatsoever from the first three drugs. The ribavirin side effects of dry skin, easily tiring from low RBC, and sleep disturbance seem not so severe and much easier to deal with without the far worse psychological side effects of interferon.
I'm very thankful for these new drugs, which I understand also have better success rates than interferon for people with cirrhosis like myself.
agree. I am glad that this drug is being superseded. I finished treatment
21 Months ago and cleared the virus. I too have been trying every route.
My Magnesium, Vit B12, and Vitamin D were low post treatment..Addressing this has helped a bit as has juicing, no gluten, no dairy no sugar. But as you remark, nothing really dents and the Medical profession does not know how to address it.....I actually had more energy on treatment than when I ceased.
It was at about 3 months after stopping treatment that I realised that the interferon had caused irreversible damage. I am still reaching for health as it is the only game in town but aside from getting enough rest and eating healthily I am not sure what can practically be done. All the best to you Simon
21 Months ago and cleared the virus. I too have been trying every route.
My Magnesium, Vit B12, and Vitamin D were low post treatment..Addressing this has helped a bit as has juicing, no gluten, no dairy no sugar. But as you remark, nothing really dents and the Medical profession does not know how to address it.....I actually had more energy on treatment than when I ceased.
It was at about 3 months after stopping treatment that I realised that the interferon had caused irreversible damage. I am still reaching for health as it is the only game in town but aside from getting enough rest and eating healthily I am not sure what can practically be done. All the best to you Simon
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Curcumin helps tremendously but it has a dark side... also you have to look at the bioavailability which is low in most products. Curcuflex is good. 3 capsules a day are sufficient.
I treated for Hep c in 2001. I never read the side effects. I was really really really sick the first month. I took matters into my own hands and did what I thought was best. I had had the disease since 1982 and asked to be tested for it. I did a workout every morning called the Body Flex and 8 minutes of Tae bo when I did that and drank AT LEAST 5 glasses of water I was good, had energy and went to work every day. When I did not drink the water I was completely exhausted. I played with my theory through the whole year of treatment. I was a heroin addict and caught the disease from whomever as I was a patient junkie who went last and I never looked as the needle went into my arm. Imagine my surprise when I had to inject myself and there was no high! OY! Delivered 3 children disease free as I carried the disease. My husband who thank god was a alcoholic so that saved my life. Was never a big drinker and if one whiskey sour was gonna get me sick the next day. Why bother! Because of his alcoholism.. we did not happily drink and I attribute my yucky feeling to that... I am very lucky. Very lucky. I am clean in more ways than one. Don't give up. Watch The Secret on Netflix and The Strangest Secret on You Tube... Drink water and any kind of workout. The Body Flex is perfect. Greer Childers its breathing and tightening. Awesome!
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