ANYONE HAVE THEIR SVR 4?

[UKgirl55]

To all of those that have done the 12 week TX of all orals. Has anyone had their SVR 4 results yet? Where are you Katla? Are you close? Hope everyone's doing well and hope to hear some GREAT news!!!

[UKgirl55]

That's brilliant Katla. Knew you would be :-))

Have I ever told you that I love your name??

[katla]

I'm quite certain I've posted this but I'm not certain and don't feel like digging.

My 12 week post was undetectable (GS 7977/BMS790052)

Thanks again for everything UKgirl...

[Dee1956]

Hi, want to chime in with Rivil, it is normal for the AST and ALT to flucuate post tx, it will normalize.
You are doing great :)

[rivll]

No, your enzymes are within normal range. As OH said, they fluctuate a bit. Avoid toxic substance (breathing in bleach fumes, for example) eat well and drink a lot of water and they will probably go down. Even so remember the numbers are normal.

[aGirl7977]

Genotype 2 Naive.. GS 7977+ Rib Trial began March,Pre treatment 9,500,000 VL. Post treatment  SVR 4 but ALT went from 13 to 23, AST from 19 to 23. Every other they had Always gone down. Any one experience this? Could this mean I may beginning to relapse?

[coraggio]

Fran,

Try to keep a positive attitude.  At this point, you do not know if your treatment outcome has been adversly affected.  The 12 wk PCR will give you a good indication whether the inf & riba are effectively suppressing the virus.  Because you stopped the Incivek at wk 8, has your clinic disccussed doing a full 48 wks of inf & riba if you are undeteced at wk 12?
In my opinion, that would enhance (not guarantee)  the chance of SVR.  

[fran4702]

What medical school hepatology center did you do this study? I am new to this forum. I am on the triple therapy invcivek started july 15.  Last friday was end of my eight week of treatment and doctor stopped my incivek due to rash. I am still on riba-800mg/day and interferon and procrit. I am really bummed because I know my SVR will now be adversely affected and I could have treatment failure. Und at week 3 genotype1a. When do you think this new drug will be out ? I am taking my treatment now through the Univ of Rochester in rochester,ny. at their hepatology center. Dr. Maliakkal is my hepatologist. My stage is 2. My viral load was 11.8mil when started. I feell so discouraged.  Fran b

[Dee1956]

This is wonderful news for all of you!
Thank you so much for sharing.  This news is encouraging to those who could not use INF

CONGRATULATIONS!!!

[gonnabhepcfree]

Congratulations!! So happy for you..I know the feeling..

[Hopinghepster]

BTB, the side effects were modest - mostly occasional fatigue, a spaced out feeling for a few hours after taking the meds in the morning, and the need to eat large lunches to stave off queasiness. I kept a pretty detailed journal describing my physical and emotional experiences on the treatment, especially in the early weeks. It's intended to be helpful to anyone doing this brilliant treatment in the future.

[BeatTheBeast]

Great news!

Did you have any side effects of treatment?  Do you have any words of wisdom for those who might do treatment in GS 7977/GS5885 study going forward?

BTB

[JDB1964]

12 weeks post treatment GS7977 + Riba UND!!

So very grateful!


Jill

[Hopinghepster]

Just got the fabulous news that I am SVR12 i.e. Cured, as 12 is the new 24, after 12 weeks of 7977 and daclatasvir, no riba. Could not be happier.

[UKgirl55]

The good news is that it's not the same compound as Gilead's nuc and more good news is that Abbott have had great success with their all orals.
Definitely a shame about BMS drug, but gotta keep postitive for what's still out there.

[pjhep80]

bad news on a Bristol Myers n all oral treatment...BMS-986094, Bristol-Myers

Despite paying big money for BMS-986094, Bristol-Myers has suspended testing on this experimental medicine for Hepatitis C after one person developed heart failure and eight others were hospitalized.

Bristol-Myers Drops Hepatitis C Drug After Patient Death

Bloomberg News

By Ryan Flinn on August 24, 2012

Bristol-Myers Squibb Co. (BMY) has abandoned an experimental hepatitis C pill it bought for $2.5 billion earlier this year after one patient died and others were hospitalized while taking the drug in a study.

Bristol-Myers will take a charge of $1.8 billion in the third quarter related to research and development of the therapy, the New York-based company said in a regulatory filing today. The drugmaker suspended testing the medicine, known as BMS-986094, on Aug. 1 after a patient developed heart failure.

[Idyllic]

Congratulations!!

http://balloonsbythebunch.net/yahoo_site_admin/assets/images/bday_balloons_bus_card.338122604.GIF

[jerialice]

all i can say is YAY! can't wait

[jewls0930]

Undected /post week 4 Abbott 450r, Ritonavir ,  Abt 333,  Abt 267,  Riba

[lowbid]

I just wanted to update on my PT 12 test and I am still undetectable.

[Revalation]

Boy this sounds good!!!
Congrats...to all who've gotten great results so far.
Wishing you the best.


Reva

[mdudley]

We are all happy for you and will be even happier if we can convince Gilead Sciences and Bristol-Myers to resume collaboration with this life-saving drug combination of GS-7977 (now named sofosbuvir) and daclatasvir (formerly BMS-790052)...

Petition update: 6595 have signed.

http://www.change.org/petitions/gilead-sciences-please-collaborate-with-bristol-myers-for-the-cure-for-hepatitis-c-now

Hope you all have a great Labor Day weekend and urge you to keep asking everyone you know to sign this petition.

Warmest regards,
Margaret

[orphanedhawk]

Wonderful news ! Thanks for letting us know.

[gonnabhepcfree]

Congratulations!!

[katla]

Wasn't sure where to post this but just had my 12 week post trial pcr and it was undetectable.