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1797925 tn?1341096204

Gilead Trial with Sofosbuvir & GS-5816

Gilead Sciences:  Twelve week Phase 2 trial of sofosbuvir + GS-5816 (without ribavirin or interferon) for genotypes 1, 2, and 3 treatment-naïve.

The Protocol Number:  GS-US-342-0102
Clinical Trial Number:  NCT01858766

Anyone else in the Gilead 12-week trial with sofosbuvir & GS-5816 (without ribavirin or interferon)?  The initial enrollment was 140 patients and I would like to connect with or hear from anyone else who may be in these trials.  Thanks!
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Avatar universal
Hmmm, placebo effect, yes, I was looking out for that, but I think there was more to it than that. My skin cleared, my gut behaved, maybe if thee is really nothing at all in the placebo pills (I really do want to know what they are made of) then something I was leaving out affected me...I stopped taking various supplements. Nerves would explain the spaced, tired, wired, adrenalin thing, but not the clear skin, and hunger, and changed poo habits! All of which went back to baseline after I stopped the meds, within a week. Now given that i thought i was cured, the 'placebo' effect should have continued? It did not, and I was disappointed, assuming I was cured but my liver was still compromised, and all the chemo had affected me.
Stronglady you are done girl, well done to you! Jenn I am hanging on your results! Good luck!
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Avatar universal
That is along the lines of what I was thinking.....
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Avatar universal
Maybe Jen..
To keep it from other drug companies????
As maybe they want to conquer th whole hep c market?

Love
Alico x
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Avatar universal
Wow
With alt at 11,
Your liver is looking pretty good.. No imflamation!!!

Fingers crossed.. At mo.. No virus at work in your liver... Just hope its all gone from the rest of you.. Then home and dry.
4 week svr good.. Just need the 12 week .. Then your clear!!!

All best.. Great news
Alico x
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Avatar universal
Hi caz,

What a bu..mer,
I really thought you had real thing..
The mind can be so strange and play tricks on us..
Placebo.. Cleared digestion..
Mind/ body..
Obviously your worry over hep c effected yor digestion, and once you thought you were tackling it.. Your digestion relaxed.

I know my blo..dy digestion is all over the place and gets worse when I get worked up and anxious.. It's a sort of repression of the fight/flight thing.. That we want to do.. But with hep c we feel powerless to flee it and without the drugs powerless to fight it. So we internalise our feelings and our gut suffers as a result.
So that's prob why your digestion and then your general energy levels were good on the placebo.
At last you thought I'm doing something to kill this bee virus, and getting on with it.
Now at least ... You can go forward and even though its another mountain to climb.. You can do it.. And do the tx in the summer!!! With good weather etc.. And hopefully come Xmas you'll be hep c free!!

All the very best to you.
Btw it just seems stupid putting people on nothing.. What does that really prove.. They've got a whole load of people on nothing.. Just trying to survive!
But that's the none sense of drug companies for you along with charging exorbitant prices.

I'm crossing fingers for dariop in uk...
No news yet..
Best of luck caz.. Keep updating .. I'm trying to keep an eye on this one as I hope it will be my saviour !!!
Probably misled!! But there has to be hope ! Otherwise were all lost!

Lots love
Alico
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Avatar universal
The Astral 2 trial doesn't have placebo so you definitely have the real deal.  And they have already said that you were SVR4 so that is very good news for you!
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