Aa
Hep C 3a EOT
hi to all,i have finiShed my tx for hep.C 2 months ago, genotype 3a,starting VL was
1 700 000 IU/ml,fibrosis F3,after 4 week VL dropped to 70,8 week undetectable-(<10IU
roche tacman,up to 8 weeks no longer checked) Duration of treatment 24 weeks.
Liver enzymes are in normal range since 6 week of treatment,ALT 40 AST 31,last 1 month EOT PCR QUALITATIVE showed undetectible, my recent enzymes are AST 27, ALT 21.
I was treated with Pegasys 180, copegus 1200 mg with BMI 22, no lowered doses never during
the tx, one exception, for the first week riba dose were 800mg,then raised the dose to 1200.Please tell me what are the chances for me to rich SVR in such conditions, going to
check next PCR after 24 days,this will be my 12 week EOT test,thanks to everyone on this
forum,without reading there I was be unable to go through the whole treatment!
sorry for spelling...
1 700 000 IU/ml,fibrosis F3,after 4 week VL dropped to 70,8 week undetectable-(<10IU
roche tacman,up to 8 weeks no longer checked) Duration of treatment 24 weeks.
Liver enzymes are in normal range since 6 week of treatment,ALT 40 AST 31,last 1 month EOT PCR QUALITATIVE showed undetectible, my recent enzymes are AST 27, ALT 21.
I was treated with Pegasys 180, copegus 1200 mg with BMI 22, no lowered doses never during
the tx, one exception, for the first week riba dose were 800mg,then raised the dose to 1200.Please tell me what are the chances for me to rich SVR in such conditions, going to
check next PCR after 24 days,this will be my 12 week EOT test,thanks to everyone on this
forum,without reading there I was be unable to go through the whole treatment!
sorry for spelling...
I just received my 12 week EOT PCR Qualitative test result-NEGATIVE,liver enzymes
also still remain in low levels,think this is good sign for my 24 week SVR.
Best wishes!!!
davetx
also still remain in low levels,think this is good sign for my 24 week SVR.
Best wishes!!!
davetx
Thank you Bali05 for the link,I am familiar with this study,I have relied on this conclusion!
Great news,congratulations,this is probably almost SVR as I know,you are on right direction,before my 3 month PCR I checked my alt level,it remained still low for this time,19U/L.
I just got my 3 months post EOT PCR results. So far so good, still UND.
Hope you will get the same result. Good luck!
mk
Hope you will get the same result. Good luck!
mk
Thank you for response, looked your Profile, it is very interesting to me.Your situation is indeed my similar, look forward to hearing your result in your path to SVR,wish you
negative PCR!
God bless.
I have pretty similar stats (my profile), except I did only Riba 800. My post EOT 3months coming in next week, will let you know how it turns out. Best wishes for all of us!
Big thanks for encouraging responses, I also pray for your health and eternal SVR, still
want to add one more,my pretreatment fibroscan score was 11.8 k/Pa,after 2 weeks
EOT-10.8, i dont know how this is good or bad,i had hoped for more decline,may be early for this time,do the following check after 6 months from the end of therapy.
It was very hard to go through whole tx with such doses,especially at the end,nausea was terrible but had no way back with my liver condition.
Best wishes Dave.
want to add one more,my pretreatment fibroscan score was 11.8 k/Pa,after 2 weeks
EOT-10.8, i dont know how this is good or bad,i had hoped for more decline,may be early for this time,do the following check after 6 months from the end of therapy.
It was very hard to go through whole tx with such doses,especially at the end,nausea was terrible but had no way back with my liver condition.
Best wishes Dave.
Your ALT looks great for 2 months post tx. I had mine done monthly after 24 month tx - I would drive down to the beach and open the results. The ALT was 60 EOT and each month after finishing tx, continued to decrease.
I was 3a, bridging fibrosis (Stage 3-4), and did the 24 weeks. I hit >43IU at week 4 and was given a 75%-80% chance (they would've been more positive if I hadn't had the bridging fibrosis. It was great that you were aggressively treated with the RIiba - I was on 1000.
Big congrats for getting through - I'm looking forward to hearing your 3 month results, but with the ALT's getting lower I think you can be cautiously optimistic. My ALT was 60 EOT and progressively lowered in a very similar fashion to yours!! Prayers coming your way from me as well!!
I was 3a, bridging fibrosis (Stage 3-4), and did the 24 weeks. I hit >43IU at week 4 and was given a 75%-80% chance (they would've been more positive if I hadn't had the bridging fibrosis. It was great that you were aggressively treated with the RIiba - I was on 1000.
Big congrats for getting through - I'm looking forward to hearing your 3 month results, but with the ALT's getting lower I think you can be cautiously optimistic. My ALT was 60 EOT and progressively lowered in a very similar fashion to yours!! Prayers coming your way from me as well!!
Your chances are very good for SVR! I'm a 3 A and I'm at 2 1/2 years SVR and was treated with the same meds...Good luck and I'll keep you in my prayers for SVR forever! (((((HUGZ))))~MM
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