Aa
Hepatitis C Genotype 3
Hi All,
My mother is diagnosed Hepatitis C Genotype 3 months before .That time HCV viral load was 47000 /ml Doctor has started injection(once a week) and ribavirin tablet (200mg 5 times a day ) .As per doctor Adivice we check HCV viral load decreased to 20000 /ml .but after completing 3 months hcv viral load was incrised to 116000 /ml .Also IL28B test result was C/T .please help me to understand the situation . i am really worried for mother helth .
My mother is diagnosed Hepatitis C Genotype 3 months before .That time HCV viral load was 47000 /ml Doctor has started injection(once a week) and ribavirin tablet (200mg 5 times a day ) .As per doctor Adivice we check HCV viral load decreased to 20000 /ml .but after completing 3 months hcv viral load was incrised to 116000 /ml .Also IL28B test result was C/T .please help me to understand the situation . i am really worried for mother helth .
That website for the liver friendly diet I mentioned is:
http://www.loveyourliver.com.au/loving-your-liver/diet.
Good luck to your Mom in treatment and on to SVR! Pat
http://www.loveyourliver.com.au/loving-your-liver/diet.
Good luck to your Mom in treatment and on to SVR! Pat
j: Sorry. My 'Happy Fingers' as my Husband calls them, touched the Post button before I was finished.
I have misplaced my Liver Friendly site, but will find it and come back and post it.
Again, I want to stress that my answer is My PERSONAL OPINION and that I am NOT a doctor or other medical practitioner.
Again, Good Luck to you and your Mom on her treatment. (I don't know if I told you but I am also Genotype 3. I just finished 24 weeks of Sovaldi and Ribavirin (on Dec 1st) and am now waiting for my Bloodwork at 12 Weeks Post EOT (End of Treatment). We are optomistic!
Pat
I have misplaced my Liver Friendly site, but will find it and come back and post it.
Again, I want to stress that my answer is My PERSONAL OPINION and that I am NOT a doctor or other medical practitioner.
Again, Good Luck to you and your Mom on her treatment. (I don't know if I told you but I am also Genotype 3. I just finished 24 weeks of Sovaldi and Ribavirin (on Dec 1st) and am now waiting for my Bloodwork at 12 Weeks Post EOT (End of Treatment). We are optomistic!
Pat
Sorry it took me so long to respond, but I had to look up the principles of ayurvedic treatment to make sure I know just what was involved.
Below I have pasted a synopsis I found, some of it, you can ignore Because you probably already know and some of it i.e., the treatment practices in the US don't apply. IF the rest in the information seems correct, then, based on that I would definitely recommend using diet - but I refer to a liver friendly diet, yoga, meditation, exercise, and massage ----BUT PLEASE NOTE: I AM NOT A DOCTOR OR OTHER MEDICAL PRACTITIONER SO THESE ARE JUST MY PERSONAL OPINIONS, based on a lifetime of experience and reading. Also,
I DEFINITELY WOULD NOT RECOMMEND THE CLEANSING AND PURIFICATION and the HERBAL TREATMENTS. Repeat, I would NOT recommend the cleansing and purification and the herbal treatments.
My reason for this is that BOTH of those directly affect the liver AND IT DOES NOT NEED ANY ADDITIONAL STRESS.
I know you are seeking ways of helping your Mom until the Sovaldi is available, and eating a liver friendly diet, rest, yoga, exercise, (to the extent that she comfortably can), meditation and massage are all useful for that, but while the cleansing and purifiaction treatment is good for many things, it would stress the already being attacked liver. The same goes for herbal treatments. There are some which might strengthen the liver, BUT THE CHANCE IS TOO GREAT THAT THE TX (treatment) WOULD CONTAIN THINGS WHICH THE LIVER IN ITS PRESENT STATE WOULD FIND TOXIC.
At the bottom of the the article on ayurvedic tx, I have pasted the browser address for a good liver friendly diet site.
***************************************************************
What might an Ayurvedic treatment plan involve?
Diet: Recommendations are individualized to a person's dosha and the season. Foods can either balance or cause imbalance to each dosha. See a list of foods thought to balance each dosha.
Cleansing and detoxification: This may be done through fasting, enemas, diets, and body treatments.
Herbal medicine: Examples of Ayurvedic herbs are triphala, ashwaghanda, gotu kola, guggul, and boswellia.
Yoga
Meditation
Exercise: Individualized to a person's constitution
Massage: Medicated herbal oils are often used.
How are Ayurvedic practitioners trained?
In India, there are many undergraduate and postgraduate colleges for Ayurveda, where the training can involve up to five years of study.
Outside of India, some people who have been trained in another health profession (e.g. medical doctor, nurse, naturopathic doctor) study Ayurveda before or after their training. Other practitioners attend Ayurvedic college only.
Currently, there are no national standards for the certification training or licensing Ayurvedic practitioners in the United States or Canada.
Because of its growing popularity, Ayurvedic treatments, particularly at spas and salons, are increasingly being performed by people who have not received formal training in Ayurveda. That's why if you are interested in consulting with an Ayurvedic practitioner, it is important to seek a qualified Ayurvedic practitioner and learn about his training.
Are there any potential concerns with using Ayurvedic medicine?
According to NCAAM, in 2004, 14 out of 70 Ayurvedic herbal remedies tested were found to contain lead, mercury, and/or arsenic at potentially harmful levels. All products were manufactured in South Asia.
In the same year, the Centers for Disease Control and Prevention received 12 reports of lead poisoning linked to the use of Ayurvedic herbal products.
A lack of research exists on the effectiveness, safety, side effects, and potential drug interactions of Ayurvedic herbal products. Although some research has been done, there have generally been problems with the design of the studies.
In North America, the use of traditional Ayurvedic practices, such as emesis, enemas, and blood cleansing, is considered highly controversial and the safety of such practices is unknown.
If you are considering Ayurveda...
Talk with your doctor first if you are considering Ayurveda.
Ayurveda should complement, not replace, conventional care. If you are experiencing any new symptoms, consult your family physician first.
Consult a qualified Ayurvedic practitioner, rather than trying to treat yourself with Ayurvedic products.
Be sure the Ayurvedic practitioner knows your full health history and is aware of all medications you are taking.
Since symptoms of dosha imbalance in alternative medicine may be linked to a number of health conditions, it's important to consult your physician if you have any health concerns. Self-treating a health condition and avoiding or delaying standard care may have serious consequences.
Sources:
Centers for Disease Control and Prevention. Lead poisoning associated with Ayurvedic medications--five states, 2000-2003. Morbidity and Mortality Weekly Report. 53.26(2004):582-584.
Centers for Disease Control and Prevention. Agency for Toxic Substances and Disease Registry. Lead Toxicity: Physiologic Effects. Agency for Toxic Substances and Disease Registry Web site. 29 March 2007 .
National Center for Complementary and Alternative Medicine, "What is Ayurvedic Medicine?." National Center for Complementary and Alternative Medicine. October 2005. National Institutes of Health. 28 Mar 2007 .
Saper RB, Kales SN, Paquin J, et al. Heavy metal content of Ayurvedic herbal medicine products. Journal of the American Medical Association. 293.23(2004):2868-2873.
*******************************************************************
I am sorrry this is so long but I wanted to back up WHY I recomend some parts and not others.
Below I have pasted a synopsis I found, some of it, you can ignore Because you probably already know and some of it i.e., the treatment practices in the US don't apply. IF the rest in the information seems correct, then, based on that I would definitely recommend using diet - but I refer to a liver friendly diet, yoga, meditation, exercise, and massage ----BUT PLEASE NOTE: I AM NOT A DOCTOR OR OTHER MEDICAL PRACTITIONER SO THESE ARE JUST MY PERSONAL OPINIONS, based on a lifetime of experience and reading. Also,
I DEFINITELY WOULD NOT RECOMMEND THE CLEANSING AND PURIFICATION and the HERBAL TREATMENTS. Repeat, I would NOT recommend the cleansing and purification and the herbal treatments.
My reason for this is that BOTH of those directly affect the liver AND IT DOES NOT NEED ANY ADDITIONAL STRESS.
I know you are seeking ways of helping your Mom until the Sovaldi is available, and eating a liver friendly diet, rest, yoga, exercise, (to the extent that she comfortably can), meditation and massage are all useful for that, but while the cleansing and purifiaction treatment is good for many things, it would stress the already being attacked liver. The same goes for herbal treatments. There are some which might strengthen the liver, BUT THE CHANCE IS TOO GREAT THAT THE TX (treatment) WOULD CONTAIN THINGS WHICH THE LIVER IN ITS PRESENT STATE WOULD FIND TOXIC.
At the bottom of the the article on ayurvedic tx, I have pasted the browser address for a good liver friendly diet site.
***************************************************************
What might an Ayurvedic treatment plan involve?
Diet: Recommendations are individualized to a person's dosha and the season. Foods can either balance or cause imbalance to each dosha. See a list of foods thought to balance each dosha.
Cleansing and detoxification: This may be done through fasting, enemas, diets, and body treatments.
Herbal medicine: Examples of Ayurvedic herbs are triphala, ashwaghanda, gotu kola, guggul, and boswellia.
Yoga
Meditation
Exercise: Individualized to a person's constitution
Massage: Medicated herbal oils are often used.
How are Ayurvedic practitioners trained?
In India, there are many undergraduate and postgraduate colleges for Ayurveda, where the training can involve up to five years of study.
Outside of India, some people who have been trained in another health profession (e.g. medical doctor, nurse, naturopathic doctor) study Ayurveda before or after their training. Other practitioners attend Ayurvedic college only.
Currently, there are no national standards for the certification training or licensing Ayurvedic practitioners in the United States or Canada.
Because of its growing popularity, Ayurvedic treatments, particularly at spas and salons, are increasingly being performed by people who have not received formal training in Ayurveda. That's why if you are interested in consulting with an Ayurvedic practitioner, it is important to seek a qualified Ayurvedic practitioner and learn about his training.
Are there any potential concerns with using Ayurvedic medicine?
According to NCAAM, in 2004, 14 out of 70 Ayurvedic herbal remedies tested were found to contain lead, mercury, and/or arsenic at potentially harmful levels. All products were manufactured in South Asia.
In the same year, the Centers for Disease Control and Prevention received 12 reports of lead poisoning linked to the use of Ayurvedic herbal products.
A lack of research exists on the effectiveness, safety, side effects, and potential drug interactions of Ayurvedic herbal products. Although some research has been done, there have generally been problems with the design of the studies.
In North America, the use of traditional Ayurvedic practices, such as emesis, enemas, and blood cleansing, is considered highly controversial and the safety of such practices is unknown.
If you are considering Ayurveda...
Talk with your doctor first if you are considering Ayurveda.
Ayurveda should complement, not replace, conventional care. If you are experiencing any new symptoms, consult your family physician first.
Consult a qualified Ayurvedic practitioner, rather than trying to treat yourself with Ayurvedic products.
Be sure the Ayurvedic practitioner knows your full health history and is aware of all medications you are taking.
Since symptoms of dosha imbalance in alternative medicine may be linked to a number of health conditions, it's important to consult your physician if you have any health concerns. Self-treating a health condition and avoiding or delaying standard care may have serious consequences.
Sources:
Centers for Disease Control and Prevention. Lead poisoning associated with Ayurvedic medications--five states, 2000-2003. Morbidity and Mortality Weekly Report. 53.26(2004):582-584.
Centers for Disease Control and Prevention. Agency for Toxic Substances and Disease Registry. Lead Toxicity: Physiologic Effects. Agency for Toxic Substances and Disease Registry Web site. 29 March 2007 .
National Center for Complementary and Alternative Medicine, "What is Ayurvedic Medicine?." National Center for Complementary and Alternative Medicine. October 2005. National Institutes of Health. 28 Mar 2007 .
Saper RB, Kales SN, Paquin J, et al. Heavy metal content of Ayurvedic herbal medicine products. Journal of the American Medical Association. 293.23(2004):2868-2873.
*******************************************************************
I am sorrry this is so long but I wanted to back up WHY I recomend some parts and not others.
Hi,
Sovaldi will be avaiable in india after JUne 2015 . Please let me know , can we try Ayurvedic treatment ( http://www.hepatitisc.in )meanwhile .
please sugge
Sovaldi will be avaiable in india after JUne 2015 . Please let me know , can we try Ayurvedic treatment ( http://www.hepatitisc.in )meanwhile .
please sugge
Hi,
Sovaldi will be avaiable in india after JUne 2015 . Please let me know , can we try Ayurvedic treatment ( http://www.hepatitisc.in )meanwhile .
please suggest
Sovaldi will be avaiable in india after JUne 2015 . Please let me know , can we try Ayurvedic treatment ( http://www.hepatitisc.in )meanwhile .
please suggest
Just wanted to write and tell you not to worry.
There are new medications that have become available and your mom will be cured of this virus. Everyday the Drs and scientists are finding new treatment
so that Hep C will no longer make your mom or anyone else sick again.
I'm so sorry that this last treatment didn't work but you must have faith that the next one will.
We are all so very lucky that they now have a cure for Hep C. I'm sure your mom is very happy to have a child like you, that cares so much.
Please know treatment that works will be in India soon.
Take Care
....Kim
There are new medications that have become available and your mom will be cured of this virus. Everyday the Drs and scientists are finding new treatment
so that Hep C will no longer make your mom or anyone else sick again.
I'm so sorry that this last treatment didn't work but you must have faith that the next one will.
We are all so very lucky that they now have a cure for Hep C. I'm sure your mom is very happy to have a child like you, that cares so much.
Please know treatment that works will be in India soon.
Take Care
....Kim
Genotype 2 & 3 were actually the easiest to treat with the highest rate of success and the shortest duration of treatment. ?although geno 3's do have a higher relapse rate than geno 2's on interferon and ribavirin. The CT allelle designation is right in the middle. The CC has the highest success with interferon, The CT is next and the TT has the poorest rate of success. These are meaningless with the new drugs as no interferon is used. The new all oral drugs have made genotype 1's the easiest to treat at this time.Do to the fact that your mom's viral load actually increased on interferon, she should not take that drug again. Here are the Valence trial results for geno 3's on sovaldi (sofosbuvir) and ribavirin:
Wishing your mom the best.
In the Phase 3 VALENCE study, 85 percent (n=212/250) of treatment-naïve or treatment-experienced patients with genotype 3 HCV who received a 24-week regimen of sofosbuvir plus ribavirin (RBV) achieved a sustained virologic response 12 weeks after treatment (SVR12). Patients who achieve SVR12 are considered cured of HCV infection.
"The VALENCE results demonstrate the high efficacy of a 24-week, sofosbuvir-based, interferon-free treatment regimen for genotype 3 HCV patients with and without liver cirrhosis," said Stefan Zeuzem, MD, Professor of Medicine and Chief of the Department of Medicine, Goethe University Hospital, Frankfurt, Germany, and principal investigator for the VALENCE study. "Notably, the majority of these patients had failed prior therapy, and sofosbuvir was able to produce a sustained virologic response."
Wishing your mom the best.
In the Phase 3 VALENCE study, 85 percent (n=212/250) of treatment-naïve or treatment-experienced patients with genotype 3 HCV who received a 24-week regimen of sofosbuvir plus ribavirin (RBV) achieved a sustained virologic response 12 weeks after treatment (SVR12). Patients who achieve SVR12 are considered cured of HCV infection.
"The VALENCE results demonstrate the high efficacy of a 24-week, sofosbuvir-based, interferon-free treatment regimen for genotype 3 HCV patients with and without liver cirrhosis," said Stefan Zeuzem, MD, Professor of Medicine and Chief of the Department of Medicine, Goethe University Hospital, Frankfurt, Germany, and principal investigator for the VALENCE study. "Notably, the majority of these patients had failed prior therapy, and sofosbuvir was able to produce a sustained virologic response."
What country does your Mother live in and WHEN did she treat? Gt 3 was, historically, the hardest to treat (not necessairly true anymore). That used to be the treatment of choice, but, if she lives in the U S and was treated within the last year, I believe a better choice would have been Sovaldi (1 600 mg pill, once a day), and Ribavirin (3 200 mg capsules twice a day). That is what my doctor has me on, as the best choice AT PRESENT, for Gt3.
Now, Bristol-Myers, Squibb have been in trials for daclatasvir (brand name Daklinza) 1 pill, once a day, PLUS Sovaldi, 600 mg once a day. Those studies are so exciting as the results are showing 98 to 100% SVR (cure) in Gt3s, in just 12 weeks! They should be going before FDA for approval either Nov 30th, or Dec 7th - I have seen both dates. This med is going to probably be off-label, but with success rates like that, it is worth fighting Ins companies for. If no Ins, the companies usually have a support program of some sort to help with the cost.
Please note that there isn't any information available yet, as Gilead has their own 1 pill combo that they tested on Gt1s, which they will probably want people to choose first.
Finally, the IL28B is the hardest.may have affected the outcome of the the injections as there has been some talk of that on the Forum. CC is the easiest to treat, CT is the middle ground and TT (MY IL28B) os the hardest. These allelea don't affect treatment on Sovaldi and the newer meds, that was specific to the interferon and interferon based injections.
Sorry this is so long but hope it helps.
Again, please tell us where (Country) and when you Mom was treated and, did/does she have fibrosis or cirrhosis and if so, what stage. Hepc is a very slow moving disease and, if she doesn't have fibrosis or cirrhosis, or is only at Stage F-1 or F-2 fibrosis, she has time to wait for the Daklinza or one of 2 or 3 other 1 pill combos which will be coming out in the next few months.
Good luck to you and your Mom! Pat
Now, Bristol-Myers, Squibb have been in trials for daclatasvir (brand name Daklinza) 1 pill, once a day, PLUS Sovaldi, 600 mg once a day. Those studies are so exciting as the results are showing 98 to 100% SVR (cure) in Gt3s, in just 12 weeks! They should be going before FDA for approval either Nov 30th, or Dec 7th - I have seen both dates. This med is going to probably be off-label, but with success rates like that, it is worth fighting Ins companies for. If no Ins, the companies usually have a support program of some sort to help with the cost.
Please note that there isn't any information available yet, as Gilead has their own 1 pill combo that they tested on Gt1s, which they will probably want people to choose first.
Finally, the IL28B is the hardest.may have affected the outcome of the the injections as there has been some talk of that on the Forum. CC is the easiest to treat, CT is the middle ground and TT (MY IL28B) os the hardest. These allelea don't affect treatment on Sovaldi and the newer meds, that was specific to the interferon and interferon based injections.
Sorry this is so long but hope it helps.
Again, please tell us where (Country) and when you Mom was treated and, did/does she have fibrosis or cirrhosis and if so, what stage. Hepc is a very slow moving disease and, if she doesn't have fibrosis or cirrhosis, or is only at Stage F-1 or F-2 fibrosis, she has time to wait for the Daklinza or one of 2 or 3 other 1 pill combos which will be coming out in the next few months.
Good luck to you and your Mom! Pat
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Herpes sores blister, then burst, scab and heal.
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Y'all, hang in there andkeep on keeping on. It should be a vailable soon.
Pat