finished treatment - first labs after

[Bill200]

Finished triple therapy (19 months of INF and Riba plus the Incivek) on Oct 26th.  Had my first labs yesterday.  ALT and AST still about running about what they've been running for a long time.  That is, AST just one or two points above normal and ALT in the middle of the normal range.  TBilli was down to 1.0 and had been running 1.3 to 1.5 so liver function is good.

Had a VL test but that won't be back until next week.  I wonder, if it still UND, what that means as far as going forward.  I know three months UND means 97% of SVR but 1 month results mean?  

Some kind of not as good news was that Gilead has tightened the criteria on entry to the SOF/LED trial.  For transplant patients you have to be really ill to get in the trial now.  I had been holding out hope that if the triple didn't work I could fallback to that.  Still they should be opening up more arms in the coming months as well as competitors coming in with their own drugs.  Hope burns eternal.  :)

best to everyone, David

[Bill200]

Will, thanks much.

[Bill200]

It came back still UND Wednesday before Thanksgiving.  Of course I've been feeling very well. :)

Will, I hadn't previously heard anything about the 1 month result being predictive.  Is there a cite for that?  I've heard the 3 and 6-month stats cited a number of times but nothing about 1 month.  Don't want to get my hopes up too much but I love to know the source of that data and boost them a little bit.

best, David

[willbb]

I know three months UND means 97% of SVR but 1 month results mean?  
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Even a little better than that David.

Week 12 response had a positive predictive value of 99.7% for predicting Week 24 SVR.,and the  1 month result you have had is only slightly below that

Well done..
Will

[mikesimon]

Sounds like great news to me!
I always expect the best.
Good Luck David,

Mike