Last day of Sovaldi tx

[Janee56]

Anyone else care to celebrate?  My last pill already went down.  Well, two more Ribavirin this evening, but then that's it.  

[Livelife777]

Blood work today. Finished treatment Monday.     Solv/Ribv.     12 weeks.   Feel so much better everyday.    Was on an emotional roller coaster pretty much the entire time and that ended once treatment stopped.  Very even temperament so that was kinda unusual.  Other side effects pretty typical.    The 1 issue was the hmg which started at 14.3, and proceeded to decline.       14.0,  12.5,  11.9,  11.5,  10.9, 10.5,  10.9, and today 3 days after ending treatment was 10.4.     The docs today said had they needed to extend treatment would have lowered the dose.     Was on 1000 mg of Ribv a day and am 5'3 and weigh 110.   Female.    Found out it takes 7-14 days for the hmg to slowly rise.     All other liver functions were normal.  Bili was a little high 1.2 and platelets 194.   Been reading the true test of cured is after 12 weeks post treatment with these new meds, but they say no, it's 6 months.    Go to Mayo Clinic.    The geno 2s were 97%. cure rate.    We will all be in that group!      I do have a question if someone can help.    Kinda confused about this........Have not had a biopsy since Mayo doesn't do them. Invasive, and there  basic 101 explanation is if you take a piece of raisin bread and blindly pull a piece out of it, you may get just bread (smooth texture) or you could get a raisin ( cirrhosis, or coarsened texture).  To many variables. Thought it was a good analogy, anyway never had one done.   Would really like to know the extent of my LD.     With all the many scans, and blood work they say I'm a Fibrosis 4.   Is that not the same as stage 1 cirrhosis?   Basically looking for if there is any kind of regeneration of existing damage.    Any thoughts would be appreciated.     So happy that many of you are on this journey since life without Hep C will be in our futures.    Still UND and will keep you guys updated.   Just a side note to Nan.....You and your husband will still be in my thoughts and prayers.    Also thanks guys for helping me get thru these last 12 weeks.    Will add  imput along the way if I can help anyone else get thru this process.          ...Kim  

[Janee56]

I just photographed my labs but have to wait till I am on pc to post it..here are results from 03 04 2014, the last labs. Will do more in a week or two. I am not exaggerating...the obsessiveness is already leaving the area. Yay. My old happy self is returning.
Hcv RNA PCR <15 NEG
These all low, but didn't concern dr.
WBC. 2.5
RBC 3.08
Hemoglobin. 9.9
Hematocrit 30.3
Platelet count 53 (I consider that high..first interferon tx it was down to 20)
Lymphocytes 23.9
I leave these to your interpretation. Hope the numbers encourage someone. I Know they will improve!
Jannie
Red Cell (high) 17.8

[imjif]

Thank you so much for your insight and suggestions.  The nausea seems to be fading and the appetites coming back so all is pretty good.  I'm definitely going to start spreading the meds out over the morning.  Taking all at once- vitamins, antidepressants, solvadi, ribavirin,pepcid  was way too much!  It has given me so much hope this week to discover this forum!  Thanks all for sharing your experiences.  We can do this!!
Jif

[hepcandme]

wow Nan. That's great!
Congrats!

[Livelife777]

Hi Jo.    Have blood draw on Fri and always get the results the same day.     Will post the hmg history as that for me was a concern.   The good news tho they have remedy's that can accommodate that issue.         Kim

[Andrea2727]

Hi there,

I just wanted to say that I am also in my last 3+ weeks of sovaldi, olysio and riba and almost quit due to the riba. My doctor did eventually reduce my dose because the side-effects were very difficult for me. Seemed I had everyone of the ones listed and then some!  I think the unpleasant sides are due manly to riba. It took a while but after about 2 weeks I started to feel better on the drug combination. My blood tested undetectable at 4 weeks I have 1b. I am waiting to hear how my labs looked last week.

To anyone starting tx, hang in there. I have heard a lot of people say they have little or no side effects, particularly with just sovalidi and olysio.  At first I thought I was going crazy! If you do have sides advocate for yourself and try to be as kind as possible to your body.

Congrats to anyone who is done, or nearly done. I am hoping for SVR for all of us!

Andrea

[JimmyMose]

Kudos! We will all be looking forward to your SVR post 12w or 24w?

My prayers and thoughts go out to everyone for their best possible or even miracle HCV resolution.  

[Janee56]

Whoot whoot!

[nan535]

Kim  You wrote:
"Hang tight everyone and Nan just want you to know that you and your husband are in my prayers and hope it all smooths out for you soon."    

Thank you so much for your prayers.
As I posted on the Sovaldi/Ribaviran +  anemia thread earlier today, the great news is they did a new HCV RNA test at 7 weeks and he is officially UNDETECTED for Hep C.  First time he has heard that word. It is just amazing. 16 more weeks to go on treatment but this is such a wonderful thing.
Thank you all for your support and wishing you all hear that word very soon!

Nan

[nursehepc]

I am glad to hear that even one day without...you feel better. You guys were scaring me with the sides (i.e., still don't have approval to start treatment). What did your Hgb start at? Just curious.  I hope that everything continues to go well for ya! Jo

[Livelife777]

This was my 1st day without my Ribv/Solvaldi combo.    Finished the 12 weeks for geno 2.    Gotta say what a difference a day makes.    Know it's still in my system but feel 100% better.     Perhaps it's a mental awareness.    Seems that many are right behind us Janee so will share some thoughts about the final few weeks.    The nausea, and other sides seemed to go away but the fatigue was insane.   Luckily easy to remedy as slept all I could and then was OK.    So.......worth hanging in there and remember eventually treatment will end.    Truly this is a life changing experience and so grateful to be part of it.   Am a patient of Mayo and on Friday have a blood draw.   Have been up and down with the Hmg so that's been a concern.   Think that's what really hit me in those final weeks.    Last check up it was back up to 10.9 so will see what Fri brings as feel as it kinda bottomed out at again the last few weeks.    Think it's a great idea to all stay in touch with results just to see how everyone is doing.    Hang tight everyone and Nan just want you to know that you and your husband are in my prayers and hope it all smooths out for you soon.            ..Kim

[Janee56]

please excuse the many typos....they should improve in number as well.  lol

[Janee56]

The interferon, riba combo sides were murderous..grand ending was an internal case of Thrush! Went to 115_6 lb.,on my 5.6" frame... but I made it thro. (Albeit eventually, not successful) . Therefore this was a cakewalk by comparison. But every side should not be brushed under the carpet. This is a time when u should listen to yourself and allow in some Poor Me..s....uh...remaining Yes! Heppers can have it All! A positive outlook but with Lloyds of Support! This go round Did involve nausea...I dealt by taking my Usual meds first thing in am, than having yogurt yum Fage..with the
HCV meds about an hour later. No coffee with the sovaldi and Riba. Drank that an hr earlier with the high BP mefs. Hehe. But seriously, no vitamins, nothing with the tx meds. Nausea stopped. Emotions and memory got worse this past 4weeks. Energy and white cells plummeted, but I know will bounce  back quickly. Anyone become obsessive or repeating themselves?   Yep.(hand in air) . At least I didn't get an interferon stutter or cuss like a sailor, this go round. Let me know how u do with nausea.

[imjif]

Congratulations!  I am on week 5 of the Solvadi and Ribavirin tx and it's been a little rough physically and mentally.  Alot of nausea, fatigue, some irritability and depression, but nothing like I hear the inteferon is.  I was wondering how the side effects were for you and if they became any more mild as time went by.  Great to hear you made it.  It gives me hope!!

[gibsongal]

Congrats!

[Janee56]

Ahaha...I Love!! It!

[candyce1953]

Haha
Yes widen that doorway, INDEED!!!

8 weeks to go here, and undetected too!

CONGRATULATIONS TO ALL!!!!

[NYCMark]

I took my final dosing this morning (simeprevir, sofosbuvir, ribavirin) to complete 12 weeks of this triple therapy.
I managed to get through without too many issues, but I'm certainly glad it's over. Congratulations to Janee, and to all those who are finishing around this time. May all your unpleasant side effects resolve quickly, and your follow-up lab tests be what we wish for!

Mark

[944s]

Congrats but get out of the doorway. There`s lots of us right behind you.Were coming in.
See you in 17 days !

[hepcandme]

I am just Ecstatic for you!
What an inspiration to everyone who is still treating. I have 3 1/2 weeks down, 8 1/2 weeks to go.
So happy to have this forum to share our experiences. I Just Got My Lab Results! is just not that fun or exciting to most people
But for us, it's the suite at the Saint Francis or a hike to Machu Pichu

[Janee56]

Oh this is so cool. I want it "stick" this time!  My Dr actually said, a couple of weeks ago..you will be Cured this time. In a bit of skeptical mood that day, I mentioned my first year of tx..he said ah, but I never made you a promise before. This time there is a 95%  cure rate, nothing quite this achievable in years past.  Well I guess so, sez I..
So...let's take that as the Solid Truth! Think I will be having some blood drawn for testing tmrw. Will have results by Thursday. Will share the info. Sure can't wait to see the whole c point

[Livelife777]

Congrats to you also.     I just took my last 3 Ribavirin pills about 3 hours ago.    Last Sovaldi this morning.    Lets hope for great results for everyone.   Bravo.  .......Kim

[almostsixty]

Congratulations! It's not easy and you have done it. Great job. I am half way there.

[Janee56]

That Riba is a real humdinger. This time it only made me emotional and obsessive. Oh boy. Lol. Nice combo..I wonder how much was truly the interferon interaction, on my first tx go roun a couple yrs back?. Who knows, right? Big difference with riba and Sovaldi. Huge But it sure it's great to have a tx not involving interferon this time. I understand from my BF, that there is another new med coming this fall, for,