RVR for Telaprevir? - FDAnews Drug Daily Bulletin

[foofighter]

Not exactly sure what this site is or if this really is "new" news for May 2 (or if they are just getting around to reporting it). Maybe just pr stuff? Anyway, I thought I would put it out there.

http://tinyurl.com/3hxduh

FDAnews Drug Daily Bulletin
May 2, 2008  | Vol. 5 No. 87


Vertex Sees Positive Interim Results for Hepatitis C Drug
A potential breakthrough treatment for hepatitis C has emerged from interim clinical trial results released by Vertex.

The company said 49 of 60 chronic hepatitis C patients who took its experimental drug telaprevir in combination with pegylated-interferon and ribavirin had a high rate of viral response at the four-week mark.

The results came from an interim analysis of an ongoing, open-label Phase IIb study and were released at the 43rd annual meeting of the European Association for the Study of the Liver.

In the clinical trial, telaprevir, also known as VX-950, combined with pegylated interferon and ribavirin, is being given to genotype 1 chronic hepatitis C patients who failed to achieve sustained virological response on pegylated interferon plus ribavirin.

[web52-1]

i was also in prove 1. 12 weeks vx950 plus 48 weeks of soc. was type 1a, started tx in august 06. was und by day 21. still clear at this time. sx were rough & lasted a good 6 months post tx, but the final result was well worth it. best wishes to you all.

[APKhaos]

There are quite a few folks on this board who participated in the three Phase II trials of telapravir; Prove 1, Prove 2, and Prove 3.

I was one fo the first to start treatment in Prove 1, went UND at day 15, and have remainied UND since that day. After 24 weeks of treament, I'n SVR at well over a year post tx and extremely grateful to Vertex for making that possible.  

[Andiamo1]

The trial talked about in your post is the one I was in!!

Eric