Aa
Serum iron
I'd be really interested in getting a better handle on the whole issue of elevated iron and what impact it might have on ultimate response to tx.
Personally, I started out with a pre-tx baseline showing elevated ferritin at 219 ng/mL (normal range 10-170). Iron was also high at 189 ug/dL (normal range 35-160). T & S percentage was 50% -- normal, but borderline. Luckily, my latest biopsy showed no iron saturation.
The research I've seen on this is provocative -- just enough to make me nervous -- but hardly conclusive. I'm still not clear about the relative importance of serum iron levels vs. tissue stores.
Anyone have any thoughts on this? Thanks!
Personally, I started out with a pre-tx baseline showing elevated ferritin at 219 ng/mL (normal range 10-170). Iron was also high at 189 ug/dL (normal range 35-160). T & S percentage was 50% -- normal, but borderline. Luckily, my latest biopsy showed no iron saturation.
The research I've seen on this is provocative -- just enough to make me nervous -- but hardly conclusive. I'm still not clear about the relative importance of serum iron levels vs. tissue stores.
Anyone have any thoughts on this? Thanks!
Hey thanks everyone for all your support and well wishes!
Doll face, I was on Peg-intron. After one year my sides are all gone except I am now hypo-thyroid which is no big deal and a fair trade :)
Good luck to everyone. I know we'll beat this.
Doll face, I was on Peg-intron. After one year my sides are all gone except I am now hypo-thyroid which is no big deal and a fair trade :)
Good luck to everyone. I know we'll beat this.
Hey thanks everyone for all your support and well wishes!
Doll face, I was on Peg-intron. After one year my sides are all gone except I am now hypo-thyroid which is no big deal and a fair trade :)
Good luck to everyone. I know we'll beat this.
Doll face, I was on Peg-intron. After one year my sides are all gone except I am now hypo-thyroid which is no big deal and a fair trade :)
Good luck to everyone. I know we'll beat this.
Sammy good to see you supporting the economy so fervently ;you can always log on to one of those get rich quick things or better yet send me the next L3000 you have and I will personally show you how to quadruple your dough in 30 days
BTW cash only please.
Lou, Unico, Lucky Lou .. you obviously have an identity crisis brewing but this too can be alleviated Send $3000(US) in cash to me and I won't tell Uncle that you are trying to move $$ out of the country ,but just investigating the realm of possibilities of creative Bisiness practices. Oh BTW no receipts are required as the $$ will return to you IF you respond in the next 43.94444 secs.
BTW cash only please.
Lou, Unico, Lucky Lou .. you obviously have an identity crisis brewing but this too can be alleviated Send $3000(US) in cash to me and I won't tell Uncle that you are trying to move $$ out of the country ,but just investigating the realm of possibilities of creative Bisiness practices. Oh BTW no receipts are required as the $$ will return to you IF you respond in the next 43.94444 secs.
Well no matter what happens at least..You look Marvaleous!! And thats the important thing. Glad to here from you. Hang in there Bro. This too shall pass. Nice to here you in better spirts
Rock ON!!!
LOU
Rock ON!!!
LOU
Sam, you just need to get an acoustic guitar and just practice John's trademark intro to almost any of his songs. Its just a 7 note bass run between open A, open D, and open E low. ( 5th string, 4th string, and 6th string). It sure sounds good and anyone can learn it ...
Wuld you believe i just wrote a letter to my Consultant asking him to confim that the sx of tx sent me nuts and thats why i blew $10000. OH LORD please make him say yes then I can cut the repayments for a while. Thing is i'm not lying, the kids cant move for toy's my wife her own car. All i got was $600 blacksuit two feathers tattooed on my arm and a $400 pair of Ray Burns. Who the hell did i think i was. I'm still here though bruv got a Japanese woman coming round later to massage my liver if she's ant good i'll give you her number.
S Hall
S Hall
AWSOME NEWS!! CONGRATULATIONS!!! WOO-HOO!! THE COWS ARE GOIN DOWN TONITE!!!
What a ride eh? I'm so happy to see that you're a winner. I'll be by with the NEW SVR bus to pick you up!
I hope you have no lingering sides left to deal with and stay happy and healthy forever!
Be well...........
What a ride eh? I'm so happy to see that you're a winner. I'll be by with the NEW SVR bus to pick you up!
I hope you have no lingering sides left to deal with and stay happy and healthy forever!
Be well...........
Honey::::Hope you get rid of that yukky pain soon.......sometimes mine would last about 1 week before going away, stay away for about 1 month, and come back again.... When ever I would stretch to the left with my right arm up over my head, I could feel the "stitch" and pulling.....even when it did not hurt at the time.
Chev:::::Hey, you have been kind of quiet lately???? Hope all is going well........been thinking about you.
Chev:::::Hey, you have been kind of quiet lately???? Hope all is going well........been thinking about you.
Thought I forgot huh? How many people you think acually know el significado? Tu es espana, si?
Luis
Luis
This could be serious, esse. I'd keep a lid on it, a nice heavy iron one, doncha think? In the meantime, take a couple tylenol and call me in the morning.
Thanks for the good feedback. I've tried all the usual tricks to reduce iron (short of phlebotomy) but this is as good as it get, apparently. And obviously these levels could be way higher...so I think I'll stop sweating it and just keeping popping and injecting. All the rest is theory, wot?
Girlwithcurl, a thousand congratulations to you on kicking this virus to smithereens. Way to go!
Girlwithcurl, a thousand congratulations to you on kicking this virus to smithereens. Way to go!
Hey Sam, How you doing Buddy? You got too much "Hutspa" (SP) to be on the sidelines. We need you in the game partner! Your the only one with a sense of humor as sick as mine! Don't leave me out here alone, please! They'll kill me!
Lou/Unico
Lou/Unico
no, pero una amante de la poesia latina americana...
Mi lucha es dura y vuelvo
con los ojos cansados
a veces de haber visto
la tierra que no cambia,
pero al entrar tu risa
sube al cielo buscandome
y abre para mi todas
las puertas de la vida.
My struggle is harsh and I come back
with eyes tired
at times from having seen
the unchanging earth,
but when your laughter enters
it rises to the sky seeking me
and it open for me all
the doors of life.
(from Pablo Neruda, TU RISA / Your Laughter )
Mi lucha es dura y vuelvo
con los ojos cansados
a veces de haber visto
la tierra que no cambia,
pero al entrar tu risa
sube al cielo buscandome
y abre para mi todas
las puertas de la vida.
My struggle is harsh and I come back
with eyes tired
at times from having seen
the unchanging earth,
but when your laughter enters
it rises to the sky seeking me
and it open for me all
the doors of life.
(from Pablo Neruda, TU RISA / Your Laughter )
From one 1A to another, That is such good news to hear. Congratulations. Since we are the hardest to treat it makes it all that much nicer to hear of someone with this genotype clearing and beating this dragon. How excited you must be.
If you don't mind me asking What type of tx were you on? How long did you treat? and How long before you started feeling better after tx? Sorry for being so nosy just getting excited about finishing up here soon. Thanks Kim
If you don't mind me asking What type of tx were you on? How long did you treat? and How long before you started feeling better after tx? Sorry for being so nosy just getting excited about finishing up here soon. Thanks Kim
Show,,,Its not bad,,,just noticeable at times,,,Like a twinge right under the rib cage and at night I notice if I stretch out on that side,,,Its sore. I have read that you can't have liver pain but just wondering what it could be right there. Anyways,,,yes If continues,,,I will definitely ask the dr at next appt..
Yeah!! Great News!! Hope you are feeling good and back to your old self as I have noticed alot seem to have lingering sides,,,,sometimes up to 1 year..
sorry to barge in on your post. Just wanted to let everyone know that my 1 year post-tx was negative!!!! I was a 1a, so just want to let you all know that another one bites the dust. I will go again in 1 year to be re-tested. Keep up the good fight.
GWC
GWC
hey! I have not researched this extensively, but my basic understanding, and the reason we are told NOT to take vitamins with iron in them, is because the liver cannot properly process is, resulting in iron overload..which is not a good thing with hepc.! People who have too much iron are encouraged to give blood to relieve themselves of some of the excess iron..but, of course.. that is not the answer for us..
Have you discussed this with your doc?? I am sure that you've probably seen this site, but just incase . here's the link...has some good info..
http://www.hepatitis-central.com/hcv/iron/toc.html
TTYL..Carol
Have you discussed this with your doc?? I am sure that you've probably seen this site, but just incase . here's the link...has some good info..
http://www.hepatitis-central.com/hcv/iron/toc.html
TTYL..Carol
Hi, all I can really offer on the subject is my own experience with iron/overload. Hemochromatosis (HHC) genes will cause the liver and other organs to absorb the iron. If both mutations are present it can be extremely dangerous and can cause cirrhosis all by itself. But for anyone with liver disease it's much worse. I found out that even one of the genes can cause additional problems for the liver with HCV.
Most docs call the high iron "acute phase reaction" to HCV. I have been told again and again, "it won't hurt you and it's nothing to worry about"!
I was looking around on line trying to figure it all out as my Ferritin had been around 1500 for over 10 years! I had many symptoms of Hemochromatosis, elevated iron/ferritin high TIBC %... (re: a gene study) except I had only one of the genes required of the two to be officially diagnosed with HHC. I was about to give up when I accidentally found a study that showed HCV patients with a high occurrence of liver iron stores with only one HHC gene present!?
It took me 3 years to find a doc that would use phlebotomy to get my iron down. He's a iron/overload specialist and said it is very harmful for all aspects of health! I trusted him and did a biopsy and CT. Results came back and sure enough my liver was absorbing iron! I don't know if 2 grams is a lot for a liver to absorb but I am waiting to see if symptomatically I will feel better with the phlebotomys and if the depression and other weird things that have been going on will subside some.
As far as TX and iron it usually drops from TX. I've heard and read different opinions as some docs get it down before starting TX and some don't. To many variables to consider like stage and progression of disease. Tx stops bone marrow production and it seems dumb to vampire someone before the TX as it seems to have the same affect on most.
It's an individual disease who knows why some clear on tx, some don't, some have bad sides, some don't, some are dying after 2 years and I'm getting better after 24 years. As usual I'm clueless! Be well and good luck to all...
Most docs call the high iron "acute phase reaction" to HCV. I have been told again and again, "it won't hurt you and it's nothing to worry about"!
I was looking around on line trying to figure it all out as my Ferritin had been around 1500 for over 10 years! I had many symptoms of Hemochromatosis, elevated iron/ferritin high TIBC %... (re: a gene study) except I had only one of the genes required of the two to be officially diagnosed with HHC. I was about to give up when I accidentally found a study that showed HCV patients with a high occurrence of liver iron stores with only one HHC gene present!?
It took me 3 years to find a doc that would use phlebotomy to get my iron down. He's a iron/overload specialist and said it is very harmful for all aspects of health! I trusted him and did a biopsy and CT. Results came back and sure enough my liver was absorbing iron! I don't know if 2 grams is a lot for a liver to absorb but I am waiting to see if symptomatically I will feel better with the phlebotomys and if the depression and other weird things that have been going on will subside some.
As far as TX and iron it usually drops from TX. I've heard and read different opinions as some docs get it down before starting TX and some don't. To many variables to consider like stage and progression of disease. Tx stops bone marrow production and it seems dumb to vampire someone before the TX as it seems to have the same affect on most.
It's an individual disease who knows why some clear on tx, some don't, some have bad sides, some don't, some are dying after 2 years and I'm getting better after 24 years. As usual I'm clueless! Be well and good luck to all...
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