Our hepatologist, head of UCSD transplant center, says yes. I choose to believe him. That said, I agree with all posters above, no drinking, drugs, etc.
I believe Sentinel13 has his old and new biopsies in his photos...reversed a lot of liver issues...?
Some info
http://www.hepatitis-central.com/mt/archives/2009/06/curing_hepatiti.html
http://m.cid.oxfordjournals.org/content/52/7/889.full
I wish I could remember who it was but I'm getting old. lol Anyways, there was recently someone on here who reached SVR and a year or so later (may have been a few years) they had a liver biopsy and their stage and grade had improved noticeably. May have improved drastically, like I said it's a vague recollection. good luck!
There are documented cases of histological improvement after SVR in cirrhotic patients.
From Clinical Care:
Cirrhosis Regression During HCV Therapy Associated With Improved Liver-Related Morbidity, Mortality During Long-term Follow-up
Posting Date: April 25, 2008
See: http://tinyurl.com/7tv4naa
Main Findings
During 10-year follow-up, incidence of liver-related events, including cancer, evident among patients with sustained virologic response (SVR), but lower than those who did not achieve SVR (P = .002)
3 deaths or transplantations due to hepatocellular carcinoma
No evidence of liver-related events among patients with cirrhosis regression, but prominent among patients without cirrhosis regression (P = .01)
No liver-related deaths or liver transplantations among patients with cirrhosis regression (P = .025 vs patients without regression)
Virologic response reached in one third of patients
SVR: n = 35 (36.4%)
No SVR: n = 61 (63.6%)
Cirrhosis regression occurred in 19% of patients
Yes: n = 18 (19%)
Follow-up: 115 ± 42 months
No: n = 78 (81%)
Follow-up: 112 ± 35 months
Median duration between pretreatment and posttreatment liver biopsy: 38 months (range: 23-69 months)
Normal prothrombin time and SVR independently associated with cirrhosis regression
Prothrombin time 92.6% of normal in patients with cirrhosis regression vs 83.2% for those without cirrhosis regression
Odds ratio: 1.1 (95% confidence interval: 1.02-1.10)
SVR 94% among those with cirrhosis regression vs 23% for those without cirrhosis regression
Odds ratio: 69.1 (95% confidence interval: 7.8-612.3)
Once the virus is cleard further damage is unlikely. There are other things that deteriate your liver such as drinking and drugs.
Can stage 2 be reversed? I have seen at least 2 people on here state that their liver biopsy improved a few years after they cleared the virus. I'm guessing they weren't drinking or doing drugs or anything like that. Not sure if it happens for everyone, but I have heard it can happen as long as you not at chirrosis already.