non responder

[nooga]

now i am non - responder  what should i do till  we get a new medicine avilable /
any thoughts please ?  alternative medicine? i cant help not thinking of this thing

[micheall]

read this: http://www.medhelp.org/posts/Hepatitis-C/Boosting-Cell-Production-to-Help-Liver-Disease/show/1694282.

[susy50]

I am on triple treatment right now and i am sooooo sick i cant really do anything this treatment is hell im on week 5 just waiting for my results of my week 4 bloodwork to see my viral load. I do have liver cirrohsis and i really dont know if this treatment doesnt work what the drs next step will be if there can even be any more steps ? I am really intrested to hear what you have to say as you do sound very passionate on this subject. I sometimes think there is no treatment that can help us unless its a transplant so what do you think about the ladies on here that are cured and they sre 5 years und ,do you think the genotype and all that makes a difference?

[suzieq2]

Interested in hearing from those non responders what medications they are having to take to treat the side effects. I am having to mess for pain, stress , and sleep. Was considers a slow responder. Ha! No such thing 7 yrs. post treatment. Look at clinical options web sight for the truth . No cure. Do not even look for at least 10 yrs. I did not reach 2 log drop in 12 weeks, went 46 weeks. Went to a hematologist rated one of best in us at the Texas liver center. Kept me on 2 more weeks , just for the heck of it. Took me off at 48 weeks, been sick ever since. They new in 2004 there was no cure for 1a,s & 1b,s this dr. In 2005 gave us a 5 percent. They lie. Wake up people , even my pharmacist hates the drug companies. Why did they keep me on , you might ask? Every prescription written money went into that Drs. Pocket , that is called a kick back. That is the world we live in. There is nothing out there for us. Clinical options is a web sight of hepatologists from all over the world , who post their monthly findings. So if you are not  cirroused don't do it , you have time. It all depends on what your biopsy says, it does slow the dragon down, but as soon as you stop treatment , it just skyrockets back & up.no there is nothing for you at this time , non responders 1a, 1b, I would be in a lot better shape right now , if I new then what I know now. They scare you. Educate yourself , don't be intimidated by Drs. They are just people. Ask the questions. If the Dr. Doesn't take time with you , leave , get biopsy & keep going to hepatologists until you find one you really like.& trust . The gastro I went to obviously was out for money, mrs. Christian. Why else would she have put me on & keep me on , until a hepatologists took me off & told me the truth. He did transplants all day every day Hcv patients. Dr. Gene Lesage , no longer in Houston Tx. Bummer, he is in Johnson city , Tennessee FYI. Plus HMO , will not test if you are a non responder . Why? Because they know treatment won't work , so why test, it's all a money game . & a big one. Why is there not the media outpouring for HCV like there was for HIV.& this virus has far surpassed HIV And going at a rapid rate. Blood Born only? I don't think so . I never did I've drugs , I believe I got it from dental work in 1985 , got sick , was diagnosed with mono , when I believe it was Hcv . Long winded, I am very passionate on this subject , for obvious reasons , it has ruined my quality of life, & treatment I believe has shortened it. I am 58 yr. young , grandmother who is missing out on some of the best years of my life because I am sick most of the time.

[suzieq2]

Interested in hearing from those non responders what medications they are having to take to treat the side effects. I am having to mess for pain, stress , and sleep. Was considers a slow responder. Ha! No such thing 7 yrs. post treatment. Look at clinical options web sight for the truth . No cure. Do not even look for at least 10 yrs. I did not reach 2 log drop in 12 weeks, went 46 weeks. Went to a hematologist rated one of best in us at the Texas liver center. Kept me on 2 more weeks , just for the heck of it. Took me off at 48 weeks, been sick ever since. They new in 2004 there was no cure for 1a,s & 1b,s this dr. In 2005 gave us a 5 percent. They lie. Wake up people , even my pharmacist hates the drug companies. Why did they keep me on , you might ask? Every prescription written money went into that Drs. Pocket , that is called a kick back. That is the world we live in. There is nothing out there for us. Clinical options is a web sight of hepatologists from all over the world , who post their monthly findings. So if you are not in cirroused

[HectorSF]

Generally speaking (depending on how advanced your liver disease is);

* Stay as healthy as possible. Don't take any substances that will cause your liver disease to progress more quickly.

* Wait for the new meds. For patients who treat with Teleprevir the SVR rate for previous non-responders with SOC is 30 - 35%. (It is probably similar with Boceprevir). This is much higher than the SRV for persons who retreat with SOC.

Hang in there.
hectorsf

[paen53]

Like the others have said, maintaining a healthy lifestyle and BMI will really help in the long run. The other thing I would add is to have your Vit D. level checked to make sure it's at its optimal level. Good for your overall health and tx outcome.

http://www.hivandhepatitis.com/2010_conference/easl/docs/0518_2010_b.html

Best wishes! Pam

[copyman]

new meds should be out this summer or sometime in 2011. In the meantime eat a low fat,sugar & salt diet. exercise and don't drink alcohol.

[adamben101]

Sorry to hear that.  There's a lot of alternative medicines out there, but keep in mind that NONE of them have proven efficacy.  I have read of some non-responders going off treatment, getting in much better shape and trying again with SOC.  How long were you treating?  The other thing is to wait for the new meds.  Estimates are that they will be available sometime between Summer 11 and 2012.  I am wrestling with what to do now, and I have not started any treatment yet.  I hope things turn around for you.  First off, stay healthy by eating healthy and not putting anything bad into your body (smoking, alcohol, etc).  Drop some weight and get a good Dr to help you along.  You will beat this.  Good luck!