Aa
Aa
A
A
A
Close
Avatar universal

viral ld

can viral load go from 1000000 to 1.500000 during first 12 weeks of IFn and RIBA
11 Responses
Sort by: Helpful Oldest Newest
223152 tn?1346978371
Do you mean go from 1 million to 1 1/2 million?  It would be possible to do so, but if it happens treatment should be discontinued.  This is not the norm.  Has it happened to you?

frijole
Helpful - 0
96938 tn?1189799858
You sure you have the zeroes and the decimal point correct?  Are you reading this from a lab report? Depending on what you are EXACTLY seeing and how it is represented in the report going from 1,000,000 (one million) to 1.5 might not be bad. Or, it could be.
Helpful - 0
Avatar universal
yes it happened to me.  My hepatologists office called today to let me know it rose from 1 million to 1.5 million and to stop taking the medicine, it wasn't working.  I have not seen the lab yet but they will mail me a copy.
Helpful - 0
96938 tn?1189799858
I gues that answers the question.  Sorry to hear it.
Helpful - 0
Avatar universal
1 million to 1.5 million is what I was told.  They're mailing me a copy of the lab.  Also I thought it might be helpfull to know I am G1a probably 14 yr. with liver condition unknown but they suspect 3 to 4 no biopsy  and told me possibly some new treatments would be out next year and maybe I could take one of those.
Helpful - 0
Avatar universal
Very sorry to hear that too.  At least you don't have to take the SOC drugs needlessly now.  I did for 72 weeks and I'm right back where I started.  Better drugs are on the way for us relapsers, non responders and null responders.  Hang in there.

Trinity
Helpful - 0
Avatar universal
I am sorry to hear of your result. Hopefully the new meds will work for you when they come out. Where you vigilant about taking your medications on time and the correct amount? have you had a biopsy and do you know what stage your liver condition is at?

Take Care,
Dave
Helpful - 0
179856 tn?1333547362
I wonder why they didn't give you a biopsy as a G1 when they think you are that late stage?  Fortunately the new drugs are very hopefully coming out in the next year and you can get on board with them and win.

I'm very sorry about your news but as Trinity said at least you found out now!
Helpful - 0
Avatar universal
I took all medication within an hour in the prescribed amount.  No biopsy, but liver suspected in 3 or 4 stage.

thank you
Helpful - 0
Avatar universal
Sorry I missed your previous information about stage 3-4 suspected. If it was me I'd want to have a biopsy to be sure of my condition. Is there a reason they aren't doing one?

Next time you treat with the new drugs you should get a 4 week viral load in my opinion.

Take care,
dave

Helpful - 0
Avatar universal
looks like your hepa made the right call. The increase of 0.17 log is not significant but basically qualifies you as an ultra null responder: ifn's effectiveness is most dramatic in the initial phase of decline. On the plus side, you only incurred a week of ifn collateral damage and now have valuable information for future planning. Unfortunately, the 1st gen  PIs scheduled for approval within the next 9 months or so critically depend on ifn as an adjunct - and you'd likely be waiting your time with those. From posts here, it seems a 0.8 drop by w4 is the neighborhood of ifn response needed for success with tela/boce. You might want to look at trials NCT01012895 and NCT01170962. Both involve a promising new drug BMS790052. The former trial is small (only 50) but specifically targeted at null responders and includes arms that combine two DAA drugs that target distinct viral proteins  and, importantly for you, does not rely on any IFN . If the wait starts to look like a long one,  you may want to look at some of the trials involving antifibrotic angiotensin receptors, eg NCT00930995 (see also discussion of anti-oxidative supplements in recent threads)
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.
Can I get HIV from surfaces, like toilet seats?