Hepatitis Social Community
1.94k Members
Avatar universal

Prilosec, Nexium Side Effects: Acid Reflux Medication

Prilosec, Nexium Side Effects: Acid Reflux Medication Heart Attack Class Action Lawsuit Investigation

A recent study found that proton pump inhibitor heartburn treatments such as Nexium, Prilosec and Prevacid may be linked to an increased risk of heart attack, heart failure or sudden cardiac death. If you or a loved one suffered a heart attack after taking an acid reflux medication, you may have a legal claim

Proton pump inhibitors (PPIs) are some of the most widely prescribed drugs in the United States, and generate around $14 billion in annual sales. Prilosec, Nexium and other PPIs work by reducing the amount of stomach acid produced by the glands in the stomach lining. These heartburn treatments also suppress the levels of nitric oxide in the cells lining the inside of the circulatory system. Lower nitric oxide levels have been associated with heart problems.

Proton pump inhibitor heartburn treatments include:
•Esomeprazole (Nexium)
•Omeprazole (Prilosec, Zegerid)
•Lansoprazole (Prevacid)
•Dexlansoprazole (Dexilant)
•Pantoprazole (Protonix)
•Rabeprazole (Aciphex)

Of these heartburn treatments, Nexium is the best-selling proton pump inhibitor. It recently became available without a prescription. Many PPIs are now available over the counter; however, acid reflux medications have not been approved for long-term use. Patients using these OTC acid reflux medications for more than two weeks should talk with their doctors.

16 Responses
Avatar universal
Avatar universal
What about people staying outside the US? will they also be compensated ?
766573 tn?1365166466

Not entirely sure what this has to do with HCV but I heard a story on NPR about this over the summer. It seemed the risk is for those who are already at risk rather than your Average Joe with no history of a cardiovascular event.


The increase in risk is about 16 to 20 percent, depending on the particular drug involved," Shah says.

Assuming that link holds up, and the risk is spread evenly throughout the population, someone with a low risk of heart attack doesn't have much to worry about. "If your risk of a cardiovascular event or a heart attack is one in a million, now it is 1.2 in a million," Shah says.
Avatar universal
About This Community:

This forum is for questions about medical issues and research aspects of Hepatitis C such as, questions about being newly diagnosed, questions about current treatments, information and participation in discussions about research studies and clinical trials related to Hepatitis. If you would like to communicate with other people who have been touched by Hepatitis, please visit our new Hepatitis Social/Living with Hepatitis forum
Avatar universal
This has to do with many of us having been or are currently on opremazole (Prilosec) As you may know, those of us with cirrhosis often suffer from nausea and can't eat. Doctors prescribe this for nausea. I thought it was a given that everyone would know that. There have been discussions and concerns about this medicine in the recent past.
Sorry I posted it. Every time I post I get a lot of grief. This is on topic and of concern to many Heppers who take this medicine.
Avatar universal
I guess. Call and check with them.
Avatar universal

That's a new one since it is for Acid reflux.
Avatar universal
Medications for nausea.

Avatar universal
So confused on this post
253566 tn?1219679699
I appreciate this post very much!

During treatment my stomach lining was destroyed and I was told that I would be on a PPI for the rest of my life. I have been on Omeprazole 20mg 2x/day since treatment and for nearly 10 years now.

INF/Riba put a hole in the lining of my stomach that will never heal (unless the liver specialist lied about that also). I have attempted to go off PPI and the acid reflux is so horrific (as I have a hole in the lining of my stomach from treatment) that the acid burn is unbearable - no home remedy works and I have tried EVERYTHING! even sleeping nearly half standing up.

As most of us PISers are in a great Catch 22. We dont trust doctors but need doctors to help us heal.

Thank you very much for this latest info. Not sure how I will carry on with it and my trusted doc - I am not in the category for a future heart attack but it is a concern.
2059648 tn?1439766665
Interesting.   I had acid reflex for years.  To Nexium for years and years.
After treating my hepatitis C….. I didn't have acid reflex any more.  Also, smoking aggravates acid reflex.  
Avatar universal
So the point is that you can join the class action suit if you or someone you know has taken the medicine and has suffered a heart attack from it. Nothing more and nothing less. I have left the info for that reason alone in case it would benefit someone.
Avatar universal
Oh and it was moved here by the moderators so I do not have control over the fact that it landed in the social section.
253566 tn?1219679699
That is interesting how TX effects individuals differently is in not?

I gave up the cancer sticks about 5 years even before it was discovered that I had HepC...
Avatar universal

Apparently the link reports a 404 error maybe healthquestions.is auto removed from link
Try adding healthquestions. between .../ and medhelp...........in the link and try.
Avatar universal
the hot link doesn't work
Do not add www in link as it will not work
Have an Answer?
Top Hepatitis Answerers
317787 tn?1473358451
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
For people with Obsessive-Compulsive Disorder (OCD), the COVID-19 pandemic can be particularly challenging.
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.