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Follow up - now indeterminate WB HSV-2

Terri, to follow up - restating basic facts as I'm not sure if this post will be connected to old post.
My results:
2010: IgG negative HSV-1; IgG 1.46 HSV-2
4/2014: IgG negative HSV-1; IgG 1.19 HSV-2
6/2014: Western Blot negative HSV-1; Indeterminate HSV-2

A few partners: 1991-1999, can't be sure of status, no contact with visible lesions
1 unprotected partner: 1999-2010, he tested negative IgG for both HSV-1 and HSV-2 in 2010 coincident with my first test
2 single encounters: 2012-2013: no visible lesion but oral contact with one not condom protected, other encounter was condom protected.
New steady partner now: We've had unprotected sex since summer 2013, he tested April 2014 IgG negative for both HSV-1 and HSV-2.

I've never had a lesion/symptom  to my knowledge.

Can I rest on my indeterminate WB result and safely assume I don't have HSV-2? I'm reluctant to keep testing. My new partner doesn't want to use condoms (we're in our 40s and monogomous) and I don't want to take anti-viral drugs unnecessarily.

U-Wash told my doc we could do yet another double sample test (again not covered by insurance) but I'm wondering to what end?


This discussion is related to Further testing? Transmission risk?.
3 Responses
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101028 tn?1419603004
I think it's probably best to just err on the side of caution and get the follow up WB.  When they have the 2nd one, they compare the two to get a better idea of if it's a true negative or not. I know it's a royal pain and expensive to do so but then you know for sure and no nagging doubts with your new partner.

just my 2 cents!
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Avatar universal
Thank you for the reinforcement.
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Avatar universal
There is a very high chance you are negative.

I think the best thing you can do is for you and your partner to examine the stats and reach a conclusion that you are most probably negative and not worry about it again.

A further Westernblot 3-6 months after the last one may result in a negative. I cannot see how you are positive based on the test results of you and your partners.
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