hello guys,
I am in the same situation. I never had any sores on genital just around mouth since I am a kid. In August my IGG for HSV1 was above 55 and HSV2 was 1.19. My md told me that it was probably a false positive and that I should retest later on. In mid october I retested and my HSV1 was around 50 whereas my HSV2 was 1.34. My doc told me he was convinced that it was a false positive. On top of that my IGG for HSV2 went up of .15. I cannot believe him I want a WB and It seems impossible to get it in NY state. I have try couple of lab nobody will allow me to draw blood and send samples. I am so pissed off. do you know any other test or place where I can go in NY to do it. Very frustrated! We live in a third world country!!!
Hey that's good news, glad the WB was able to provide you with clarity.
I received the results of my western blot today after 3 weeks of waiting and it was negative for hsv 2.
Your thinking is correct. We do see a number of people with HSV1 triggering a low positive HSV2. Maybe it is related to cross reactivity or maybe just a false positive from elements in the blood other than true antibodies.
I saw a rule of thumb years ago that suggested a ratio of more than 10 between ELISA results of HSV1 and HSV2 was indicative of the lower value being a negative. This may not be of the fullest credibility but it seems to apply more often than not.
Again the figure is so low that without genital lesions I'd assume this is a false positive. A Westernblot would put the issue behind you for sure.
Welll, I just got the results from my follow up and now it's 1.15. My doctor is on vacation until next week and I am going to ask about a WB when she gets back. Still no symptoms on myself or my boyfriend. The nurse that called me said it wasn't a false positive if it's still showing up. Wound up explaining to her with me having it orally the low reading does indicate I might not have it. Especially with it still being so low a month later. This is frustrating.
This looks almost certainly to be a false positive, even to the extent of not worrying about it any further, particularly if your partner is negative for HSV2.