Ok, thanks guys. I really appreciate it. I'm getting there with trying to believe I'm HSV-free, but Bigtime I'm sure you understand the worry I am having with strange genital symptoms and no explanation. I have read your posts. My GI doc did say that anal issues could effect the vaginal area since they are separated by such a thin wall. He also said a ID doc could do a DNA/RNA test that is more accurate than antibody tests when testing for hsv and the reason they aren't routine is because they are to expensive. He suggested I go that route for confirmation. Is there any truth to what he said about that testing?
Yes you have had an ELISA tests which describes the method. Essentially this involves the antibody combining with the antigen and a colored enzyme and the color density is compared to the control testing well, expressed as a ratio.
The <0.91 is a clear negative for these sensitive tests.
Western Blot is 99% accurate per U of W around 6 months from exposure. I also took the WB around 22.5 weeks from exposure. It's as close to 99% you will get.
If you're negative at 22 weeks then you should not be worrying as you took the best antibody test available at the respected time-frames for the most accurate result.
It is this kind of information that worries me I tested negative on WB at 22 weeks (154 daysor so). I worry I took the WB too soon now. I know the odds are in my favor that this is accurate, but it keeps me doubting just a bit due to my strange unexplained symptoms.
Thank you both for the detailed explanation. I am confused a bit - first time I got the test from a local lab and another time from STDTestExpress (labcorp). One gave a value for HSV1 and 2 , another just displays <0.91 for both. Both are worded as HSV1&2 Igg type specific.Now is this one the ELISA? I haven't seen ELISA specifically mentioned in either of reports..
For ELISA IgG, the .5 mark is around 23 days. At 40 days, it's .8.
FYI, WB takes 100 days to get to .5, and hits .8 at 120. WB takes a *lot* longer to register seropositivity. Everyone be careful advising WB confirms immediately after early ELISA tests as this might create excessive false negatives.
About 50% of infected people would test positive at around 4 weeks post the actual infection.
This does not mean that you have a 50% chance of having been infected. A lot of people who are negative take the tests to be sure. Hence it is probably something like 80% plus of people who test negative after 4 weeks are actually negative.