Aa
igg value increase for HSV I and II Combine Elisa test
Hello,
I am an inhabitant of a country where it seems that medical tests worn out by time are more popular. I have been to several clinics and hospitals, and all of them offer Elisa combined tests for HSV I and II for igg and igm antibodies. While I know igm tests are useless, my question is related to the igg factor.
About a year ago I was involved in unprotected sex with a partner whom I had known for a while and trusted completely. We broke up and then I waited three months to get tested because I had learnt that igg antibodies take time to develop. When I tested after three months, the combined result for HSV I and II igg value was 0.35 which is clearly negative.
I have not been involved sexually ever since, and then for safety's sake I got re-tested in December (which would be about 13 months since last sexual encounter). This time I did the test in another clinic and the value for igg antibodies for combined HSV I and II came out as 0.74
While the result is still negative, I am worried about the increase in the value. Most of the forums here state that a value under 0.90 would mean there is no herpes infection, still I would like to know why there has been an increase in the igg level? Does this mean there is a verrrry slow seroconversion happening (which is still not positive even a year after sexual activity) or is it a given fact that every time the same subject gets tested and is negative for herpes, the index value could still be anything between 0.1 to 0.8?
Basically put- Can I safely assume I have no HSV infection, or do I take a test again three months later to be sure?
I would be really happy if I obtained some information on this. Thanks!
I am an inhabitant of a country where it seems that medical tests worn out by time are more popular. I have been to several clinics and hospitals, and all of them offer Elisa combined tests for HSV I and II for igg and igm antibodies. While I know igm tests are useless, my question is related to the igg factor.
About a year ago I was involved in unprotected sex with a partner whom I had known for a while and trusted completely. We broke up and then I waited three months to get tested because I had learnt that igg antibodies take time to develop. When I tested after three months, the combined result for HSV I and II igg value was 0.35 which is clearly negative.
I have not been involved sexually ever since, and then for safety's sake I got re-tested in December (which would be about 13 months since last sexual encounter). This time I did the test in another clinic and the value for igg antibodies for combined HSV I and II came out as 0.74
While the result is still negative, I am worried about the increase in the value. Most of the forums here state that a value under 0.90 would mean there is no herpes infection, still I would like to know why there has been an increase in the igg level? Does this mean there is a verrrry slow seroconversion happening (which is still not positive even a year after sexual activity) or is it a given fact that every time the same subject gets tested and is negative for herpes, the index value could still be anything between 0.1 to 0.8?
Basically put- Can I safely assume I have no HSV infection, or do I take a test again three months later to be sure?
I would be really happy if I obtained some information on this. Thanks!
Thank you so much. I really appreciate the help I have received here. Thanks again.
Not really, only a theoretical chance that the blood test doesn't detect your particular antibodies. You are negative for HSV. The combined tests are quite notorious for false positives, a proportion of people who test low positive on combined tests then test negative with type specific testing.
Thank you so much for the assurance. However, if you could answer one last question from me I would be grateful :) :
Is it possible for Igg levels to seroconvert to positive even after 13 months after the sexual encounter? If so, what are the possibilities of such a thing happening ( as in, is it rare, or is it common and expected)?
Is it possible for Igg levels to seroconvert to positive even after 13 months after the sexual encounter? If so, what are the possibilities of such a thing happening ( as in, is it rare, or is it common and expected)?
Hi and yes you can assume your negative. Slight raises would not be any concern. Anything belfow 1 is negative.
Have an Answer?
You are reading content posted in the Herpes Community
Herpes spreads by oral, vaginal and anal sex.
Herpes sores blister, then burst, scab and heal.
STIs are the most common cause of genital sores.
Millions of people are diagnosed with STDs in the U.S. each year.
STDs can't be transmitted by casual contact, like hugging or touching.
Syphilis is an STD that is transmitted by oral, genital and anal sex.
