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ALT AST Insanely High

Initially started as identification of bilirubin in urine because it was rather dark in color. Blood work then showed AST and ALT levels in excess of 1500 and 2000. All other bloodwork is completely normal, and frankly desireable. Cholesterol good, glucose good, tested clear on all Heps A,B,C. Ultrasound of gall bladder and liver showed no obstructions, cysts, stones, tumors or blockages. Basically an "unremarkable" scan. Last time levels were checked, they were still above 1500 and 2000. But only those two...I had a hepatic vein and artery scan/ultrasound and still awaiting results. Feel a little drained and blah, but don't know if that's just psychological because this is going on. Don't live on farm, don't take dietary supplements and haven't been sick in years nor do I or have I taken any tylenol in the recent months. Eyes are slightly yellow, so their is slight jaundice but not getting noticeable worse or better. Not sure if I should be here or not because the internet could end up just scaring the crap out of you. But wanted to hear if anyone else out there had any experience with similar issues and what actions were taken, if any aside from just the passage of time and letting things heal themselves and run their course...

Update: latest ultrasound of hepatic vein and artery all normal. Also should be noted that I don't drink at all and haven't for years. Have really been pushing the water/fluids and been getting a lot of rest.  Got blood checked again today, and a week after the results above, values are now:

AST was 1566, now 2346
ALT was 2082, now 2643

Bilirubin was 4.0, now 6.7

Think I need a more comprehensive scan of gallbladder? Almost has to be a stone in there doesn't it?? Also, starting to have an odd taste in my mouth. Can't tell if it's bitter or metallic, but definitely not normal.


What is going on??????  Any thoughts experts?
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Avatar universal
If you're not being seen by a hepatologist I think you should be,
There is something going on with your liver and it needs to be diagnosed.
Hepatologists are liver specialists and are frequently associated with liver transplant centers or large teaching hospitals. I am in no way suggesting that you need a transplant. It is just that the best liver doctors are frequently affiliated with transplant centers and they do treat non-transplant patients as well. I don't think you should take a "wait and see" approach. I'd be proactive and find out what's going on with you soon.

Good luck,
Mike
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Avatar universal
Have you got your ferritin level checked? I wonder if you have hemocromatosis?
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Avatar universal
Have you got your ferritin level checked? I wonder if you have hemocromatosis?
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Avatar universal
Saw a gastrointerologist today.  Running about 14 other labs to check for auto immune hepatitis among other things.  May be even doing a liver biopsy.  Have rules out gall issues.  Something going on with liver.  Still trying to figure it out.  I definitely would like answers.  Was is the typical waiting period and success rate/rejection etc. for transplant?
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Avatar universal
negative on hemocromatosis.  Thanks for the suggestion and thought.  They did check that.
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Avatar universal
Autoimmune disorders are a definite possibility so it's good that they're looking at that.
If you don't have access to a hepatologist then a gastroenterologist is the next best option. I must say that I'd feel better if you were seeing a hepatologist.
I think it's rather premature to be talking about transplant. I will say that liver transplantation can be very successful. I was transplanted in June 2000 and I'm doing well.

I wish you the very best of luck.

Mike
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