Elevated Liver Enzymes

[suewith]

What medications may cause elevated liver enzymes?

[JudyR395]

my sister-in-law had elevated liver enzymes and couldn't think of any meds she was on that would raise her numbers.  She decided to lower her consumption of diet cola thinking the aspertame might be causing probs and her numbers did go down.  When my liver numbers tested higher, I also cut the aspertame and my numbers went down.  Is it a coincidence or not, I don't know.

Good luck, JudyR

[Bob368]

Pain relief medications such as:

    * aspirin,

    * acetaminophen (Tylenol),

    * ibuprofen (Advil, Motrin),

    * naproxen (Naprosyn, Naprelan, Anaprox, Aleve),

    * diclofenac (Voltaren, Cataflam, Voltaren-XR)), and

    * phenylbutazone (Butazolidine)

Anti-seizure medications such as:

    * phenytoin (Dilantin),

    * valproic acid (Depakote, Depakote ER, Depakene, Depacon),

    * carbamazepine (Tegretol, Tegretol XR, Equertro), and

    * phenobarbital

Antibiotics such as:

    * tetracyclines, [for example, tetracycline (Achromycin)]

    * sulfonamides,

    * isoniazid (INH) (Nydrazid, Laniazid)

    * sulfamethoxazole (Gantanol),

    * trimethoprim (Trimpex; Proloprim, Primsol)

    * nitrofurantoin (Macrodantin; Furadantin; Macrobid),

    * fluconazole (Diflucan ) and some other anti-fungals, etc.

Cholesterol lowering drugs such as:

    * the statins:

          o lovastatin (Mevacor, Altocor),

          o pravastatin (Pravachol),

          o atorvastatin (Lipitor),

          o fluvastatin (Lescol),

          o rosuvastatin (Crestor),

          o simvastatin (Zocor), and

    * niacin

Cardiovascular drugs such as:

    * amiodarone (Cordarone),

    * hydralazine (Apresoline)

    * quinidine (Quinaglute, Quinidex), etc.

Other drugs

Anti-depressant drugs of the tricyclic type

With drug-induced liver enzyme abnormalities, the enzymes usually normalize weeks to months after stopping the medications.

Take care,

Bob :)

[ggc17]

Hi Bob, have you heard anything about PPi's increasing enzyme levels? I am on Pantoprazole 2 years and just recently have elevated ALT.  Regular blood tests over 10 years and have never been elevated till now.

[Careful35]

I do not know if they cause elevated liver enzymes but studies have shown a link between the use of PPIS and liver disease .