What are Ceftin, Flagyl, and Doxlcycline side effects?

[LazyMoose]

I will be starting these three at once orally very in a few days. Could anyone share any side effects they had and the herxing feel with these?  The Dr said they can be tough on some people that was it nauseating , headaches, absolutely no alcohol ect.

And what did you do to help cope with any side effects?

It would help me to know what might possibly be around the corner for me so I can work thru it. I have to work regardless of how I feel (not an option), so your info will help me prepare getting thru the work day.

thanks all in advance

[LazyMoose]

Well for now I'm taking Ginger , it helps with stomach issues a little supposedly.

I might go back to D-Limonine which is the beast natural anti GERD stomach coating you can get.

The Ceftin (generic of that) made me feel a little wierd, kind of anxious, didnt sleep very well from it. I took it with a snack at 9 PM and took my probiotic at 6 with dinner. Going to try some alcohol free NyQuil sleep syrup tonight.

[mojogal]

I had to result to medicine that coats your stomach either something like zantac or in my case I had a script because I have a tendency to get ulcers and a script for nausea when it was really bad.

[LazyMoose]

What can be done, if anything, to lesson possible nausea from these meds, - besides taking with food.

[LazyMoose]

My thoughts exactly. It makes more sense to start these 3 meds in a staggered fashion rather than all at once. I was surprized the LLMD did not say to do it that way.

[Ricobord]

I recommend that you do not start multiple meds at once. The herx could be quite unpleasant, not to mention that you won't know which med is causing any bad reactions.  My doc has me wait a week between new antibiotics. I'm about to start 2 new ones, but I'm only going to wait 3 days in between as I've taken both before.

I now start at new med at night when I don't have a lot of responsibilities the next day.  Since you have to work, perhaps you can start on a Friday night (assuming you don't work on weekends).  If Flagyl is the one you're most concerned about, perhaps you could start that one last.

[cave76]

Although you 'probably' had hydronephrosis before you started taking Cipro, have you seen this? It's rare but if true the continuation of Cipro may be enhancing your hydronephrosis.

I'M NOT A DOCTOR SO THAT'S JUST AN OFF-HAND GUESS. MAYBE YOU'E ALREADY DISCUSSED THAT WITH YOUR DOCTOR--- THE BEST THING TO DO, OF COURSE!

Article
Bilateral hydronephrosis from ciprofloxacin induced crystalluria and stone formation.

N Chopra, P L Fine, B Price, I Atlas
Departments of Urology and Internal Medicine, Morristown Memorial Hospital, Morristown, New Jersey 07960, USA.
The Journal of Urology (Impact Factor: 3.75). 09/2000; 164(2):438. DOI:10.1097/00005392-200008000-00040
Source: PubMed

This site referenced the above article and also lists other drugs that may induce hydronephrosis.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1508366/

[ChitChatNine]

How long does the rash typically last?  Mine is faded to a tan color.

[ChitChatNine]

Yes, I have taken Cipro this past year more than any person should, but it was for documented --potentially life threatening -- UTI or kidney stone related infections including hydronephrosis.

I stay away from any of the fluro's at all cost and beg for an alternative antibiotic because of the warning above. But some of my infections have been so serious there's the risk/benefit.   "They" love to state it's applicable moreso over Age 60 and my reply is "don't care", not so sure it's coincidence I tore two tibial tendons w/o cause. But what I can tell you without a doubt is my pain level is much worse when "on" Cipro than off it.

I also started at my Uro's direction taking Magnesium and Vit B6 and a diuretic for my kidney stones.  So, not sure if that's helping the pain or just being off that darn Cipro and being on Doxy for the newly dx'd Lyme.

PS:  I've had the kidney stone issues since 2005 and been on/off Cipro & even Levaquin for many years.  I'm allergic to Macrobid,

C~

[cave76]

Cipro and Levaquin both are in the same category. In fact, I've read some instances where Levaquin is even worse.

I took both! They might have helped with Bart. but they certainly did more damage than good for me.
"The FDA states that the damage may occur very soon into the administration of the drugs and the damage may be permanent."

Yep. Permanent for me. :(

[LazyMoose]

I'm hoping to stay clear of Cipro.

One of my main symptoms is already tendon issues, I dont want to make it worse.

[cave76]

Chit Chat---- didn't  you say you have taken Cipro?



"FDA Warning: Cipro May Rupture Tendons
Agency Issues 'Black Box' Warning for Antibiotics Known as Fluroquinolones"

"July 8, 2008 -- Federal regulators are ordering new warnings on Cipro and similar antibiotics because of increased risk of tendinitis and tendon rupture.

The new warnings apply to fluoroquinolones, a class of antibiotics that includes the popular drug Cipro. The FDA has told companies that the drugs must now carry "black box" warnings alerting doctors and patients that the drugs can increase risk of tendinitis and tendon rupture in some patients.

Fluoroquinolones have carried similar warnings for years, but officials say they continue to receive reports of safety problems. A "black box" warning is the FDA's sternest warning."

"Most of the tendinitis and tendon ruptures affect the Achilles tendon, behind the ankle. But the agency has also received reports of tendinitis and ruptures in the shoulder and hand"

"We have seen continuing reports of tendon rupture so we are trying to increase awareness," says Edward Cox, MD, director of the FDA's Office of Antimicrobial Products.

The warning applies to drugs of the fluoroquinolone class, including Cipro, Cipro XR, Proquin XR, Levaquin, Floxin, Noroxin, Avelox, Factive, and marketed generics."
http://www.webmd.com/osteoarthritis/news/20080708/fda-warning-cipro-may-rupture-tendons

********************

"Apparently there has been a change to the Black Box Warning for Floroquinolones. The FDA announced on August 15, 2013, that fluoroquinolone drugs such as Levaquin, Cipro and Avelox will be required to change packaging inserts to contain a warning for severe, permanent and disabling peripheral neuropathy. The FDA states that the damage may occur very soon into the administration of the drugs and the damage may be permanent.

If you are wondering what peripheral neuropathy is, this is the description from the FDA: Peripheral neuropathy is a nerve disorder occurring in the arms or legs. Symptoms include pain, burning, tingling, numbness, weakness, or a change in sensation to light touch, pain or temperature, or the sense of body position. It can occur at any time during treatment with fluoroquinolones and can last for months to years after the drug is stopped, or even be permanent."
http://www.cipro-poisoning.com/2013/09/fda-announces-new-black-box-warning.html

http://www.webmd.com/osteoarthritis/news/20080708/fda-warning-cipro-may-rupture-tendons

[jehermer]

so had cipro and levaquin in the past,lost 1 tenon in each shoulder due to rupture,have joint and tendon pain when tsking certain antibiotics,recently amox clav,guess you can be sensitive to My penicillin too.all drs look at me like im crazy when i tell them im. not tolerating an rx,huh? anyway,i usually feel better about later in day 1 or 2 then by day three its excruciating bordering on unbearable,what to do? hope you have better luck ya al

[cave76]

Ceftin and doxy gave me herxes but  not the worst ones I ever had. But I never took them together.

Flagyl---- whole nuther story!! First and ONLY case of Lyme rage that I ever had! Very scary and I stopped it immediately. But I probably would have stopped it soon anyway. Horrible emotional/brain/nervous system problems.

But other can tolerate it fairly well. You won't know until you, yourself, try it.

That's a fairly  hefty amount of drugs at one point. I'm glad you'll have a doctor to oversee it.

[ChitChatNine]

I'm only on doxy, but I have to tell you after reading this post it makes perfect sense that "something" else was going on for a very long time because I have been on a myriad of abx for serious kidney-related issues (stone related) since March and I swear that each course of abx caused my feet/tendon issues (that are somewhat chronic due to healing tibial tendon tears) to hurt a lot more!  

I'd go off the abx and be so much better.

Now that I'm on Doxy specifically for Lyme I have been pain free for about 5 days in my feet .. I am like a new person. So I hope it goes this way for you, too.

I take Prevacid as needed (script strength)

So my old thyroid friend ........................ we meet again!

C~

[mojogal]

I have been on Flagyl and Doxy. Since I get ulcers a lot, I take a medication daily that coats my stomach therefore I never had side effect. You can not drink with Flagyl. Even using products with alcohol in it could cause problems.

Everyone herxes differently but I get pains all over in all my joints, chills and basically you feel like you have the flu. When I first took doxy, I would throw up but I don't anymore.

Hope that helps. Your herxes could be much easier because I have the MTHFR mutated gene which affects your ability to detox properly.